切换至 "中华医学电子期刊资源库"

中华介入放射学电子杂志 ›› 2018, Vol. 06 ›› Issue (04) : 347 -351. doi: 10.3877/cma.j.issn.2095-5782.2018.04.015

所属专题: 文献

综述

常见血管内栓塞材料的临床应用进展
李炜1, 倪才方1,()   
  1. 1. 215006 苏州大学附属第一医院介入科
  • 收稿日期:2018-09-16 出版日期:2018-11-01
  • 通信作者: 倪才方
  • 基金资助:
    国家自然科学基金青年科学基金项目(81501563); 江苏省青年医学人才项目(QNRC2016711); 苏州科技局民生科技项目(SYS201611)

Clinical application and research progress of common embolic materials in transarterial embolization

Wei Li1, Caifang Ni1,()   

  1. 1. Department of Vascular and Interventional Radiology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China
  • Received:2018-09-16 Published:2018-11-01
  • Corresponding author: Caifang Ni
  • About author:
    Corresponding author: Ni Caifang, Email:
引用本文:

李炜, 倪才方. 常见血管内栓塞材料的临床应用进展[J]. 中华介入放射学电子杂志, 2018, 06(04): 347-351.

Wei Li, Caifang Ni. Clinical application and research progress of common embolic materials in transarterial embolization[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2018, 06(04): 347-351.

血管内栓塞术是一种经导管向靶血管内注入栓塞材料,使靶血管闭塞的技术。常见的血管内栓塞材料可分为固体栓塞材料与液体栓塞材料两大类。不同栓塞材料的物理、化学性质大多不同。熟悉这些栓塞材料的优点和缺点,并掌握其使用方法与作用机制,有助于在临床应用中根据不同的需求选择合适的栓塞材料。本文综述了常见血管内栓塞材料的特点与应用。

Transarterial embolization (TAE) is a technique by which embolic materials are injected into the target vessel through a catheter to occlude the target vessel. Currently, embolic materials commonly used in TAE can be divided into two categories: solid embolic materials and liquid embolic materials. The physical and chemical properties of different embolic materials are different. To be familiar with the advantages and disadvantages of these embolic materials, as well as the methods and mechanisms, is helpful for clinicians to select appropriate embolic materials according to different needs in clinical application. This article reviews the characteristics and application of the embolic materials commonly used in TAE.

[1]
Verret V,Ghegediban SH,Wassef M, et al. The arterial distribution of Embozene and Embosphere microspheres in sheep kidney and uterus embolization models[J]. J Vasc Interv Radiol, 2011, 22(2):220-228.
[2]
Derdeyn CP,Moran CJ,Cross DT, et al. Polyvinyl alcohol particle size and suspension characteristics[J]. Am J Neuroradiol, 1995, 16(6): 1335-1343.
[3]
Germano IM,Davis RL,Wilson CB, et al. Histopathological follow-up study of 66 cerebral arteriovenous malformations after therapeutic embolization with polyvinyl alcohol[J]. J Neurosurg, 1992, 76(4):607-614.
[4]
Stampfl S,Bellemann N,Stampfl U, et al. Arterial distribution characteristics of Embozene particles and comparison with other spherical embolic agents in the porcine acute embolization model[J]. J Vasc Interv Radiol, 2009, 20(12):1597-1607.
[5]
Laurent A. Microspheres and nonspherical particles for embolization[J]. Tech Vasc Interv Radiol, 2007, 10(4):248-256.
[6]
Hao MZ,Lin HL,Chen QZ, et al. Safety and efficacy of transcatheter arterial chemoembolization with embospheres in treatment of hepatocellular carcinoma[J]. J Dig Dis, 2017, 18(1): 31-39.
[7]
沈云峰,廖予妹.子宫动脉栓塞术在妇产科中的应用[J/CD].中华介入放射学电子杂志, 2015, 3(1):56-59.
[8]
Duvnjak S,Ravn P,Green A, et al. Uterine fibroid embolization with acrylamido polyvinyl microspheres: prospective 12-month clinical and MRI follow-up study[J]. Acta Radiol, 2017, 58(8):952-958.
[9]
Chua GC,Wilsher M,Young MP, et al. Comparison of particle penetration with non-spherical polyvinyl alcohol versus trisacryl gelatin microspheres in women undergoing premyomectomy uterine artery embolization[J]. Clin Radiol, 2005, 60(1):116-122.
[10]
Siskin GP,Beck A,Schuster M, et al. Leiomyoma infarction after uterine artery embolization: a prospective randomized study comparing tris-acryl gelatin microspheres versus polyvinyl alcohol microspheres[J]. J Vasc Interv Radiol, 2008, 19(1):58-65.
[11]
Yu SC,Cho CC,Hung EH, et al. Prostate artery embolization for complete urinary outflow obstruction due to benign prostatic hypertrophy[J]. Cardiovasc Intervent Radiol, 2017, 40(1):33-40.
[12]
施昌盛,杨庆,李成, 等. Embosphere微球联合弹簧圈栓塞治疗大咯血的疗效分析[J/CD].中华介入放射学电子杂志, 2017, 5(4):269-272.
[13]
朱国庆,虞希祥,肖池金, 等. Embosphere微球联合碘油肝动脉栓塞治疗原发性肝癌破裂大出血25例疗效分析[J]. 介入放射学杂志, 2014, 23(2):156-158.
[14]
李京雨,张新国. 甲状腺动脉栓塞治疗甲状腺机能亢进[J]. 中华放射学杂志, 2001, 35(3):202-204.
[15]
Facciorusso A. Drug-eluting beads transarterial chemoembolization for hepatocellular carcinoma: Current state of the art[J].World J Gastroenterol, 2018, 24(2):161-169.
[16]
Kim HC. Radioembolization for the treatment of hepatocellular carcinoma[J]. Clin Mol Hepatol, 2017, 23(2):109-114.
[17]
金三宝,陈忠,司捷旻, 等. 肾动脉栓塞致下肢栓塞一例报告[J]. 中华泌尿外科杂志, 2003, 24(7):486.
[18]
Cheong JY,Kong TW,Son JH, et al. Outcome of pelvic arterial embolization for postpartum hemorrhage: A retrospective review of 117 cases[J]. Obstet Gynecol Sci, 2014, 57(1):17-27.
[19]
金泳海,刘一之,倪才方, 等. 骨盆骨折合并盆腔大出血的急诊栓塞治疗[J]. 临床放射学杂志, 2006, 25(9):862-865.
[20]
官彬,廖先国,文鹏程, 等. 肾癌外科根治性切除术前经动脉插管栓塞的临床价值[J]. 重庆医学, 2015(22):3072-3075.
[21]
张勇,周玉梅,陈淑君, 等. 明胶海绵颗粒联合凝血酶预防CT引导下卵巢癌穿刺活检术后针道出血[J]. 介入放射学杂志, 2016, 25(5):412-415.
[22]
Goldstein HM,Wallace S,Anderson JH, et al. Transcatheter occlusion of abdominal tumors[J]. Radiology, 1976, 120(3):539-545.
[23]
吕朋华,王立富,王书祥, 等. 经导管组织黏合剂结合弹簧圈栓塞脾动脉瘤[J]. 介入放射学杂志, 2011, 20(9):737-740.
[24]
高见书,张国兵,周国伟, 等. 电解脱弹簧圈封堵先天性冠状动脉-肺动脉瘘30例临床疗效分析[J]. 介入放射学杂志, 2018, 27(5):400-403.
[25]
Dudeck O,Bulla K,Wieners G, et al. Embolization of the gastroduodenal artery before selective internal radiotherapy: a prospectively randomized trial comparing standard pushable coils with fibered interlock detachable coils[J]. Cardiovasc Intervent Radiol, 2011, 34(1):74-80.
[26]
Bechara CF,Weakley SM,Kougias P, et al. Percutaneous treatment of varicocele with microcoil embolization: comparison of treatment outcome with laparoscopic varicocelectomy[J]. Vascular, 2009, 17(Suppl 3):S129-S136.
[27]
Dutton JA,Jackson JE,Hughes JM, et al. Pulmonary arteriovenous malformations: results of treatment with coil embolization in 53 patients[J]. AJR Am J Roentgenol, 1995, 165(5): 1119-1125.
[28]
Prasad V,Chan RP,Faughnan ME. Embolotherapy of pulmonary arteriovenous malformations: efficacy of platinum versus stainless steel coils[J]. J Vasc Interv Radiol, 2004, 15(2 Pt 1): 153-160.
[29]
Falagas ME,Nikou SA,Siempos II. Infections related to coils used for embolization of arteries: review of the published evidence[J]. J Vasc Interv Radiol, 2007, 18(6):697-701.
[30]
Nakakuma K,Tashiro S,Hiraoka T, et al. Studies on anticancer treatment with an oily anticancer drug injected into the ligated feeding hepatic artery for liver cancer[J]. Cancer, 1983, 52(12):2193-2200.
[31]
Ramsey DE,Kernagis LY,Soulen MC, et al. Chemoembolization of hepatocellular carcinoma[J]. J Vasc Interv Radiol, 2002, 13(9 Pt 2):S211-S221.
[32]
Lencioni R. Chemoembolization for Hepatocellular Carcinoma[J]. Semin Oncol, 2012, 39(4):503-509.
[33]
中国抗癌协会肝癌专业委员会. 原发性肝癌规范化诊治专家共识[J]. 临床肿瘤学杂志, 2009, 14(3):259-269.
[34]
中华人民共和国卫生和计划生育委员会医政医管局. 原发性肝癌诊疗规范(2017年版)[J]. 传染病信息, 2017, 16(3):705-720.
[35]
Mabed M,Esmaeel M,El-Khodary T, et al. A randomized controlled trial of transcatheter arterial chemoembolization with lipiodol, doxorubicin and cisplatin versus intravenous doxorubicin for patients with unresectable hepatocellular carcinoma[J]. Eur J Cancer Care(Engl), 2009, 18(5):492-499.
[36]
Lo CM,Ngan H,Tso WK, et al. Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma[J]. Hepatology, 2002, 35(5):1164-1171.
[37]
Lencioni R,de Baere T,Soulen MC, et al. Lipiodol transarterial chemoembolization for hepatocellular carcinoma: A systematic review of efficacy and safety data[J]. Hepatology, 2016, 64(1):106-116.
[38]
Pollak JS,White RI. The use of cyanoacrylate adhesives in peripheral embolization[J]. J Vasc Interv Radiol, 2001, 12(8):907-913.
[39]
Koch MJ,Stapleton CJ,Agarwalla PK, et al. Open and endovascular treatment of spinal dural arteriovenous fistulae: a 10-year experience[J]. J Neurosurg Spine, 2017, 26(4):519-523.
[40]
Wajswol E,Jazmati T,Contractor S, et al. Portal vein embolization utilizing N-butyl cyanoacrylate for contralateral lobe hypertrophy prior to liver resection: A systematic review and Meta-analysis[J]. Cardiovasc Intervent Radiol, 2018, 41(9):1302-1312.
[41]
Kwon JH,Han YH. Efficacy and safety of superselective trans-catheter arterial embolization of upper and lower gastrointestinal bleeding using N-butyl-2-cyanoacrylate[J]. Emerg Radiol, 2018, 25(2):111-120.
[42]
Jahan R,Murayama Y,Gobin YP, et al. Embolization of arteriovenous malformations with Onyx: clinicopathological experience in 23 patients[J]. Neurosurgery, 2001, 51(6):1525-1526.
[43]
Graif A,Vance AZ,Garcia MJ, et al. Transcatheter embolization of type I endoleaks associated with endovascular abdominal aortic aneurysm repair using ethylene vinyl alcohol copolymer[J]. Vasc Endovascular Surg, 2017, 51(1):28-32.
[44]
Müller-Wille R,Heiss P,Herold T, et al. Endovascular treatment of acute arterial hemorrhage in trauma patients using ethylene vinyl alcohol copolymer(Onyx)[J]. Cardiovasc Intervent Radiol, 2012, 35(1):65-75.
[45]
Lenhart M,Paetzel C,Sackmann M, et al. Superselective arterial embolisation with a liquid polyvinyl alcohol copolymer in patients with acute gastrointestinal haemorrhage[J]. Eur Radiol, 2010, 20(8):1994-1999.
[1] 王艳秋, 汪龙霞, 徐虹, 李秋洋, 何萍, 刘勤. 盆腔淋巴囊肿超声引导下不同介入治疗方法疗效分析[J]. 中华医学超声杂志(电子版), 2022, 19(09): 953-956.
[2] 魏小勇. 原发性肝癌转化治疗焦点问题探讨[J]. 中华肝脏外科手术学电子杂志, 2023, 12(06): 602-607.
[3] 刘中百, 任勇军. 肝细胞癌的介入治疗现状及进展[J]. 中华消化病与影像杂志(电子版), 2023, 13(02): 111-115.
[4] 李世凯, 梁佳, 何艳艳, 于毅, 李天晓, 常金龙, 贺迎坤. 兔颈动脉粥样硬化性狭窄模型在介入治疗的应用进展[J]. 中华介入放射学电子杂志, 2023, 11(04): 357-362.
[5] 张德伟, 雷毅, 江哲宇, 王黎洲, 许国辉, 周石. 杂交手术治疗下肢深静脉血栓合并下肢急性动脉血栓一例[J]. 中华介入放射学电子杂志, 2023, 11(04): 380-384.
[6] 林加文, 印于, 杨俊, 朱晓黎, 王万胜. 肝动门静脉瘘合并腹水一例[J]. 中华介入放射学电子杂志, 2023, 11(03): 289-291.
[7] 吴雅琴, 莫伟, 向华, 李琴, 李兰. 肝癌患者介入治疗穿刺处出血影响因素的真实世界研究[J]. 中华介入放射学电子杂志, 2023, 11(02): 117-122.
[8] 曾嘉, 何东风. 介入栓塞材料在肝癌治疗中的研究进展[J]. 中华介入放射学电子杂志, 2023, 11(01): 62-67.
[9] 张正宇, 谢兴武, 周雪惠, 陈光斌. DSA引导下经皮动脉栓塞治疗腹壁下动脉出血一例[J]. 中华介入放射学电子杂志, 2023, 11(01): 82-83,88.
[10] 周璐, 王庆, 兰斌. 介入治疗医源性髂动静脉瘘一例[J]. 中华介入放射学电子杂志, 2023, 11(01): 84-88.
[11] 阴捷, 王驰, 刘玥, 李艳华. 儿童肝脏血管瘤的介入治疗方法及疗效的初步探讨[J]. 中华介入放射学电子杂志, 2023, 11(01): 6-11.
[12] 陈丹丹, 潘文志, 陈莎莎, 张源, 张晓春, 李明飞, 周达新, 葛均波. 结构性心脏病年度报告2022[J]. 中华心脏与心律电子杂志, 2023, 11(03): 129-140.
[13] 孙相利, 许真真. 经皮冠状动脉旋磨术在冠状动脉重度钙化病变介入治疗中的应用[J]. 中华老年病研究电子杂志, 2023, 10(02): 33-36.
[14] 姜新鹏, 李晓明, 杨航, 宫一宸, 傅元豪, 傅瑜, 张喆. 单纯经胸超声心动图引导卵圆孔未闭封堵术早期安全性及有效性分析[J]. 中华脑血管病杂志(电子版), 2023, 17(04): 320-324.
[15] 连万成, 姚京, 吴泽涛, 何毅, 伍健明, 张猛. 血流导向装置治疗颅内未破裂动脉瘤的疗效与影响因素分析[J]. 中华脑血管病杂志(电子版), 2023, 17(01): 31-36.
阅读次数
全文


摘要