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中华介入放射学电子杂志 ›› 2016, Vol. 04 ›› Issue (02) : 59 -62. doi: 10.3877/cma.j.issn.2095-5782.2016.02.001

所属专题: 文献

神经介入

介入再通治疗非急性期基底动脉闭塞的中长期随访研究
贺迎坤1, 李天晓1, 王子亮1, 常凯涛1, 朱良付1, 薛绛宇1, 白卫星1,(), 李钊硕1, 许斌1   
  1. 1. 450001 郑州大学人民医院介入科脑血管病区,河南省人民医院国家高级卒中中心,河南省介入治疗中心
  • 收稿日期:2016-02-13 出版日期:2016-05-01
  • 通信作者: 白卫星
  • 基金资助:
    河南省重点科技攻关项目(152102310416、162102310268); 河南省卫生科技攻关项目(201403191)

Medium and long term follow-up of revascularization and stenting of nonacute basilar artery occlusion

Yingkun He1, Tianxiao Li1, Ziliang Wang1, Kaitao Chang1, Liangfu Zhu1, Jiangyu Xue1, Weixing Bai1,(), Zhaoshuo Li1, Bin Xu1   

  1. 1. Cerebrovascular Division of Interventional Therapy Center, Zhengzhou University People's Hospital, Zhengzhou 450003, China
  • Received:2016-02-13 Published:2016-05-01
  • Corresponding author: Weixing Bai
  • About author:
    Corresponding author: Bai Weixing, Email:
引用本文:

贺迎坤, 李天晓, 王子亮, 常凯涛, 朱良付, 薛绛宇, 白卫星, 李钊硕, 许斌. 介入再通治疗非急性期基底动脉闭塞的中长期随访研究[J]. 中华介入放射学电子杂志, 2016, 04(02): 59-62.

Yingkun He, Tianxiao Li, Ziliang Wang, Kaitao Chang, Liangfu Zhu, Jiangyu Xue, Weixing Bai, Zhaoshuo Li, Bin Xu. Medium and long term follow-up of revascularization and stenting of nonacute basilar artery occlusion[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2016, 04(02): 59-62.

目的:

评价介入再通治疗非急性期基底动脉闭塞的中长期临床疗效。

方法:

收集2010年2月—2012年4月在我中心行介入再通治疗的闭塞超过24 h的非急性期基底动脉闭塞患者12例。记录围手术期并发症、随访期间短暂性脑缺血发作及卒中发生情况,使用非参数秩和检验比较手术前后及随访期间的改良Rankin量表(mRS)评分变化情况。

结果:

12例患者中有11例闭塞动脉(91.7%)成功开通。围手术期并发症发生2例,导致患者病情加重。8例患者获得影像学随访,中位随访时间12(6~30)个月,再狭窄2例,均为症状性。12例患者获得临床随访,中位随访时间51.5(0.5~73)个月,再发同侧性卒中2例,同侧性短暂性脑缺血发作1例。存活患者中,术后1周的mRS评分低于术前,术后3个月的mRS评分低于术后1周,差异均有统计学意义(P<0.05)。

结论:

介入再通治疗非急性期基底动脉闭塞可在中远期预防再发缺血事件的发生,同时术后3月内患者的残疾功能改善明显,但再狭窄问题值得进一步关注。

Objective:

To evaluate the medium and long term outcome of revascularization and stenting of nonacute basilar artery occlusion.

Methods:

12 cases of nonacute basilar artery occlusion for over 24 hours treated by endovascular revascularization in our center were retrospectively collected and analyzed. Complications and recurrent ischemic events during the follow-up period were recorded. The modified Rankin scale (mRS) scores were used to compare the relative changes of pre- and post-procedure.

Results:

Among the 12 patients, 11 (91.7%) obtained successful recanalization. However, 2 patients developed procedural complications that worsened their situation. 8 patients received imaging follow-up during the median 12 months, restenosis occurred in 2 cases, and both are symptomatic.In the subsequent clinical follow-up after the procedure, 2 ipsilateral strokes and 1 ipsilateral transient ischemic attack occurred. The mRS scores decreased significantly in the first 3 months after the procedure in survivors.

Conclusions:

Revascularization and stenting of nonacute basilar artery occlusion can prevent recurrent ipsilateral ischemic event and improve recovery, but re-occurring stenosis should draw more attention.

表1 患者各个阶段的mRS评分比较分析
图1 典型病例(40岁男性)手术前后DSA和CTA图示
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