To investigate the efficacy, safety and feasibility of interventional embolization in the treatment of secondary nephrogenic ectopic hyperparathyroidism.

The anatomic location and arterial blood supply of ectopic parathyroid gland were evaluated by high frequency ultrasound, 99mTc-MIBI parathyroid radionuclide imaging, enhanced CT or enhanced MRI before operation, and the supplying artery was blocked by interventional embolization, resulting in gradual ischemic necrosis and loss of function.

After interventional embolization, the level of parathyroid hormone (PTH) decreased rapidly, the serum calcium and phosphorus also decreased rapidly, and the clinical symptoms such as skin pruritus and general bone pain were obviously relieved in one case.In another case, because of the blood supply artery was not clear and it was difficult to cooperate during the operation, only part of the vascular embolization was completed, and the indexes such as PTH, serum calcium and phosphorus decreased temporarily, but the final effect was not good.

Interventional embolization for the treatment of ectopic parathyroid is a minimally invasive, simple, reliable and safe method. The key to success is to clear the anatomic location and arterial blood supply of ectopic parathyroid gland before operation and to completely embolize the blood supply during operation, but its long-term effectiveness needs further evaluation.