To investigate whether there was a difference in gender-based outcomes among patients with HCC who underwent transcatheter arterial chemoembolization (TACE) combined with locoregional ablation therapy.

A retrospective analysis was conducted on 806 patients with HCC who were treated with TACE combined with local ablation in Beijing You'an Hospital affiliated to Capital Medical University from January 1, 2012 to December 31, 2016. Standard propensity score matching was performed to create two highly comparable groups. The cumulative recurrence-free survival (RFS) and overall survival (OS) rates were calculated by Kaplan-Meier method, and the Cox proportion hazard model was conducted to screen for independent predictive factors for indicating recurrence and long-term prognosis of HCC patients.

Women had better 1, 3, and 5-year RFS rates (79.0%, 54.6%, 49.6% vs 68.4%, 40.4%, 33.4%, P < 0.001), which was consistent with the consequences of data processed by PSM method. There were different risk factor spectrum for recurrence between men and women. Age, tumor number, tumor size, neutrophils, globulin, GGT, together with alpha fetoprotein (AFP) could influence recurrence for men, however for women, only age and globulin were independent predictors.

Women have a better prognosis than men. Prognosis difference with respect to gender may indicate the significance of gender-based stratification in preoperative evaluation and prognostic management of HCC patients.

To investigate the application value of 3D rotational DSA in prostate artery embolization (PAE).

A total of 73 cases of patients with benign prostatic hyperplasia (BPH) treated with PAE were selected in the Department of Interventional Therapy, The Fifth Affiliated Hospital of Zhengzhou University from August 2016 to June 2020. All patients were accepted conventional two-dimensional DSA (2D-DSA). Subsequently, focusing on the orthotopic blood vessel image, the image was acquired by rotating the C-arm, and the acquired imageswere sent to the 3D workstation to complete the reconstruction of the prostate artery. All pictures were reviewed by two physicians with advanced professional titles in the Department of Interventional Therapy. The number, origin, and anastomotic branch with adjacent arteries of the prostatic arteries in conventional 2D-DSA and 3D rotational DSA imaging were observed.

The Kappa value of 2 doctors in the interventional department reading the film to identify the consistency of the prostate artery was 0.734. 148 prostate arterieswere demonstrated in 142 lateral internal iliac arteries by conventional 2D-DSA and 3D rotational DSA. The 3D rotational DSAdemonstrated 143 (96.62%, 143/148), while the conventional 2D-DSA demonstrated 116 (78.38%, 116/148), the difference was statistically significant (χ² = 22.517, P < 0.001). 28 (18.92%, 28/148) prostate arteries in 26 lateral internal iliac arteries (18.31%, 26/142) were only identified by the 3D rotational DSA, while 4 (2.82%, 4/142) in 4 lateral internal iliac arteries were only identified by the conventional 2D-DSA, the difference was statistically significant (χ² = 20.182, P < 0.001). 6 (4.92%, 6/122) prostate arteries were indentified by the conventional 2D-DSA while excluded by 3D rotational DSA. The origins of 10 prostate arteries in 9 lateral internal iliac arteries (6.16%, 9/146) were only accurately identified by 3D rotational DSA. 57 prostate arteries which were anastomose with adjacent arteries were accurately identified by 3D rotational DSA, which was higher than that of the conventional 2D-DSA (27.59%, 32/116), the difference was statistically significant (χ² = 4.278, P = 0.039). By analysis of 3D rotational DSA image, the optimal projection angle of 143 prostate arteries (the patient's body was inclined to the same side) was 20°~45°, among which, the optimal projection angle of 61 (42.66%, 61/143) prostate arterieswas31°~35°, and then was 26°~30°, which was 38 (26.57%, 38/143).

3D rotational DSA applied in PAE surgery can more clearly identify the number and origin of prostate artery and its complex anatomical structure. Therefore, it is of great significance to improve the effect of embolization.

TTo evaluate the effect of percutaneous transluminal stenting (PTS) in treatment of central venous stenosis (CVS).

Clinical data of 29 patients who were diagnosed as CVS, manifested by imaging examination, and treated by PTS were collected and reviewed retrospectively. Follow-up was performed at the first, third and sixth month after discharge. The imaging examination, clinical results, complications, and second treatment were reviewed.

36 treatment of PTS were performed in the patients. The technical success rate was 97.2%, and clinical effective rate was 94.4%. A total of 48 stents were implanted, including 36 bare stents and 12 covered stents. There was no complication observed among these cases. After 3-38 months of follow-up, restenosis of the stent occurred in 10 patients after PTS, and re-intervention was performed. The restenosis rate of bare stent after PTS (45.8%) was significantly higher than that of covered stent (10.0%) (χ²=3.852, P=0.046). Moreover, the restenosis rate after PTS was 57.1% in patients with chronic renal failure (CRF) undergoing hemodialysis through autologous arteriovenous fistula, and 19.0% in non-CRF patients, with significant difference (χ2=5.256, P=0.022). Compared with patients with post-operative regular anticoagulant therapy, the restenosis rate of stent in patients without regular anticoagulant therapy was higher (26.67% vs 100%, χ2=8.311, P=0.004).

PTS was effective in treatment of patients who suffered with CVS.The restenosis rate when performed with covered stent was lower than that with bare stent; however, the restenosis rate following PTS was higher in patients with CRF receiving hemodialysis treatment. Moreover, post-operative regular anticoagulant therapy was critical.

聚桂醇注射液已被广泛应用于静脉畸形的临床治疗，疗效及安全性已得到验证。儿童处于生长发育阶段，个体差异大，尽管儿童静脉畸形的硬化治疗原则与成人相似，但在临床诊疗中尚存在一些关键的区别，对这些慢性疾病的管理及对儿童生长发育的影响都需要慎重考虑。结合静脉畸形硬化治疗现状以及儿童静脉畸形特点，文章就儿童静脉畸形硬化治疗的基本概念、聚桂醇注射液应用及操作规范等方面进行专题研讨，参考相关文献，经国内专家多次深入研讨，最终制定《聚桂醇注射液治疗儿童静脉畸形中国专家共识》，以指导临床应用。

To evaluate the safety and short-term efficacy of Pipeline Flex embolization device (PED Flex) for treatment of complex intracranial aneurysms.

The clinical data of131 patients with complex intracranial aneurysms who were treated with PED Flex in Zhengzhou university People's Hospital from June 2018 to August 2019 were retrospectively analyzed. Periprocedural complications were analyzed. Modified Rankin Scale (mRS) was used to evaluate clinical outcomes and the O’Kelly-Marotta (OKM)grading scale was used to evaluate imaging outcomes.

A total of 131 patients with159 complex aneurysms were treated with 144 PED Flex, and the procedure success rate was 100%. Adjunctive coiling was used in 52 aneurysms and 107 cases used the stent only. Postprocedural neurological complication rate was 3.1% (4/131). Among them, the thromboembolic and hemorrhagic complication was 2.3%(3/131) and 0.8%(1/131), respectively. There were no deaths occurred. The mRS were 0 in 101 patients, 1 in 25, 2 in 4,4 in 1 and the disability rate was 0.8%(1/131) at discharge. A total of 61 patients with 80 aneurysms obtained the imaging follow-up with a median of 6.0(3-9) months. Fifty-seven aneurysms were completely occluded (grade D of OKM grading scale) with a complete occlusion rate of 71.3%(57/80). The in-stent stenosis was observed in 4 (6.6%, 4/61) patients, but no patients were symptomatic. Eighty-seven patients obtained the clinical follow-up with a median of 9.0 (2-21) months, and the mRS were 0 in 78 patients, 1 in 5, 2 in 3 and 4 in 1.

The treatment of complex intracranial aneurysms with PED Flex is safe with a high procedure success rate, and it is efficient with a high complete occlusion rate during the 6-months follow-up.

To study the feasibility and safety of diatal transradial access (dTRA) for transcatheter arterial chemoembolization (TACE).

This retrospective study enrolled 15 patientswho received TACE through distal transradial access from November 2020 to July 2021. The rate of successful puncture and successful introduction of sheath, access site-related hemorrhage or hematoma, dissection of aorta and radial artery occlusion (RAO) was evaluated.

All of the 15 patients were successfully punctured into the left diatal radial artery. Only one patient had to transform to transfemoral access (TFA) TACE due to vasospasm. One patient was found bleeding at the puncture site after surgery. No dissection of artery or RAO was observed.

Our preliminary experience with dTRA for TACE demonstrates excellent feasibility and safety. However, further randomized controlled trial is still needed to verify our preliminary experience.