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中华介入放射学电子杂志 ›› 2020, Vol. 08 ›› Issue (03) : 233 -236. doi: 10.3877/cma.j.issn.2095-5782.2020.03.008

所属专题: 文献

血管介入

下肢深静脉血栓患者凝血酶Ⅲ的测定及意义
孔杰1, 赵伯翔1, 公茂峰1, 陆照璇1, 周阳逸1, 陈亮1, 苏浩波1, 楼文胜1, 陈国平1, 顾建平1, 何旭1,()   
  1. 1. 210006 江苏南京,南京医科大学附属南京医院,南京市第一医院介入血管科
  • 收稿日期:2020-04-25 出版日期:2020-08-25
  • 通信作者: 何旭

Detection and significance of antithrombin Ⅲ in patients with deep venous thrombosis of lower extremities

Jie Kong1, Boxiang Zhao1, Maofeng Gong1, Zhaoxuan Lu1, Yangyi Zhou1, Liang Chen1, Haobo Su1, Wensheng Lou1, Guoping Chen1, Jianping Gu1, Xu He1,()   

  1. 1. Department of Vascular and Interventional Radiology, Affiliated Nanjing Hospital of Nanjing Medical University, Nanjing Municipal First Hospital, Jiangsu Nanjing 210006, China
  • Received:2020-04-25 Published:2020-08-25
  • Corresponding author: Xu He
  • About author:
    Corresponding author: He Xu, Email:
引用本文:

孔杰, 赵伯翔, 公茂峰, 陆照璇, 周阳逸, 陈亮, 苏浩波, 楼文胜, 陈国平, 顾建平, 何旭. 下肢深静脉血栓患者凝血酶Ⅲ的测定及意义[J]. 中华介入放射学电子杂志, 2020, 08(03): 233-236.

Jie Kong, Boxiang Zhao, Maofeng Gong, Zhaoxuan Lu, Yangyi Zhou, Liang Chen, Haobo Su, Wensheng Lou, Guoping Chen, Jianping Gu, Xu He. Detection and significance of antithrombin Ⅲ in patients with deep venous thrombosis of lower extremities[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2020, 08(03): 233-236.

目的

研究下肢深静脉血栓形成患者和非血栓疾病患者的抗凝血酶Ⅲ(ATⅢ)活性差异及意义。

方法

回顾性分析2017年1月至2018年12月于本院治疗下肢深静脉血栓形成患者252例及非血栓性疾病患者212例,收集各组的临床资料,测量所有患者的ATⅢ活性,比较两组间ATⅢ活性的差异。

结果

深静脉血栓组ATⅢ活性(IU/dL)为85.16±15.58,非血栓疾病组为87.92±19.09,两组ATⅢ差异无统计学意义。

结论

本组研究未发现深静脉血栓组及非血栓组ATⅢ活性差异有统计学意义,对深静脉血栓患者测量ATⅢ活性可对抗凝方案提供参考。

Objective

To investigate the difference of the plasma antithrombin Ⅲ (ATⅢ) between deep venous thrombosis and non-thrombosis patients.

Methods

A retrospective analysis was performed on the clinical data of 252 patients with deep vein thrombosis of lower extremities and 212 patients without thrombotic diseases in our hospital from January 2017 to December 2018. The ATⅢ level in all patients was measured,and the difference of ATⅢ level was compared between the two groups.

Results

There is no significant difference in ATⅢ level (IU/dL) between the deep venous thrombosis group (85.16±15.58) and the non-thrombosis group (87.92±19.09).

Conclusions

In this study, there was no difference in ATⅢlevel between deep venous thrombosis group and non-thrombosis group. The measurement of ATⅢ level in patients with deep vein thrombosis can provide a reference for anticoagulant therapy.

图1 非血栓组和深静脉血栓组相比,非血栓组年龄更高且差异有统计学意义
图2 非血栓组和深静脉血栓组相比,非血栓组男性比例更高且差异有统计学意义
图3 非血栓组和深静脉血栓组相比,非血栓组糖尿病比例更高且差异有统计学意义
图4 非血栓组和深静脉血栓组相比,非血栓组高血压比例更高且差异有统计学意义
图5 非血栓组和深静脉血栓组相比,AT3活性的差异无统计学意义
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