To evaluate the predictive value of ^99mTc-DAPA renal dynamic imaging for stent placement for atherosclerotic renal artery stenosis.

For 45 patients with atherosclerotic renal artery stenosis, a total of 54 renal artery underwent stent placement (percutaneous transluminal renal angioplasty and stent, PTRAS), ^99mTc-dapa renal dynamic imaging was performed within 2 weeks before surgery and 6 months after operation respectively. The glomerular filtration rate of the affected side was measured by Gates method (glomerular filtration rate, GFR), creatinine, blood pressure. According to the results of preoperative GFR determination of renal function can be divided into GFR level Ⅰ (GFR≥30 ml/min), GFR level Ⅱ (15 ml/min≤GFR<30 ml/min) and GFR level Ⅲ (GFR<15 ml/min). GFR, renal perfusion and function of the affected kidney before and after operation were analyzed. Preoperative and postoperative changes in blood pressure, types and doses of antihypertensive medicines, and serum creatinine serum creatinine changes were analyzed.

Postoperative GFR was evidently improve, especially in GFR Ⅰ, GFR Ⅱ, renal perfusion increased higher than that in the GFR Ⅲ with statistically significant difference (P<0.05). The number of patients with GFR Ⅰ and GFR Ⅱ postoperative effective blood pressure control was higher than that of patients with GFR Ⅲ with statistically significant differences (P>0.05). Postoperative systolic blood pressure decreased from (165±18) mmHg to (138±12) mmHg, and diastolic blood pressure decreased from (100±12) mmHg to (88±8) mmHg. The dose of antihypertensive medicines was lower than that before operation with statistically significant differences (P<0.05). There was no significant difference in serum creatinine before and after operation (P>0.05). Unilateral treatment was better than bilateral treatment with statistically significant differences (P<0.05).

^99mTc-DAPA dynamic renal imaging can be used to evaluate the efficacy of stent implantation for atherosclerotic renal artery stenosis.