To explore the clinical application value by using XperCT technology to improve the accuracy in percutaneous transhepatic biliary drainage (PTCD) of malignant obstructive jaundice.

Eighty-seven cases with malignant obstructive jaundice from October 2018 to October 2019 in our hospital were enrolled.All patients were divided into two groups according to the random number table method. Forty-two cases as Group A were underwent XperCT examination during PTCD. Forty-five cases as Group B had no XperCT examination during PTCD. t test and χ2 test were used to compare the success rate of first puncture of target bile duct (segmental bile duct to be punctured before operation), the rate of successful avoidance of important organs (including intrahepatic tumor), number and time of puncture, radiation exposure dose and postoperative complications (hemorrhage, bile fistula, pancreatitis, infection, etc.) between the two groups.

Both groups were punctured successfully. The success rate of the first puncture of the target bile duct were 88% in group A and 51% in group B with significant difference (P<0.05). The success rate of avoiding important organs were 95% in group A and 78% in group B (1 case died of massive hemorrhage from puncture tumor) with significant difference (P=0.018), the number and time of puncture, radiation dose , postoperative complications (hemorrhage, infection, bile fistula, pancreatitis, etc.) were 14.02±3.23 s, 1.09±0.29 times, 6.21±1.35 mGy, 0.07±0.26, in group A respectively, and 63.20±6.22, 1.75±0.90 times. 21.33±7.38 mGy, 0.17±0.38, in group B respectively, and the group A was superior to group B.

The application of XperCT in PTCD can make up for the deficiency of single fluoroscopy, guide interventional physicians to carry out accurate treatment, avoid the occurrence of serious complications, and ultimately improve the therapeutic effect of PTCD.