Calculation of radial dose distribution of 125I radioactive particle chain by 3D treatment planning system

doi:10.3877/cma.j.issn.2095-5782.2018.02.013

Abstract

Abstract:

Objective:

To calculate the radial dose distribution of ¹²⁵I radioactive particle chain with different lengths, distances and activities using the three dimensional treatment planning system (3D-TPS) .

Methods:

The single, double and three ¹²⁵I radioactive particle chains were implanted into the equivalent human body membrane and scanned by MSCT. The radial dose distribution of particle chains was calculated on 3D-TPS after the scanned images were imported.

Results:

The dose field of ¹²⁵I radioactive particle chain was cylindrical, which dropped fast if the distance was more than 1 cm from the ¹²⁵I chain. The regression equations of single, double and three ¹²⁵I cumulative dose (dose, Gy) , seed activity (activity, mCi) and distance from the center (cm) were: ln dose=43.3 activity-24.2 distance+48.4; ln dose=95.4 activity-55.8 distance+112.0; ln dose=138.0 activity-79.8 distance+160.5.

Conclusion:

The dose field of ¹²⁵I radioactive particle chain is mainly affected by the seed activity and radial distance from center, while the affection of ¹²⁵I radioactive particle chain length is weak. The measurement results can provide reference for clinical application.

Key words: 3D treatment planning system, Computer aided system, Particle chain, Radiation dose

Dechao Jiao, Zhihui Zhong, Rongfang Niu, Xinwei Han, Bo Ma, Jianzhuang Ren, Zhan'guo Sun, Juanfang Liu, Jin Shi. Calculation of radial dose distribution of ¹²⁵I radioactive particle chain by 3D treatment planning system[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2018, 06(02): 154-157.

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https://zhjrfsxdzzz.cma-cmc.com.cn/EN/Y2018/V06/I02/154

Figures/Tables 5

References 15

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粒子链旁开距离	?	粒子活度(mCi)
粒子链旁开距离	?	0.3	0.5	0.7	0.9
1 cm	单链	30.5	50.6	70.6	90.6
?	双链	69.2	114.3	161.7	207.2
?	三链	98.4	166.6	230.2	293.1
1.5 cm	单链	17.4	28.4	39.4	50.4
?	双链	36.1	60.4	84.3	107.6
?	三链	52.2	88.4	121.9	155.3
2.cm	单链	10.3	17.7	24.4	30.6
?	双链	21.9	36.4	50.5	65.2
?	三链	32.6	54.6	73.7	95.4
2.5 cm	单链	7.4	11.1	15.6	20.8
?	双链	14.4	23.5	32.6	41.1
?	三链	20.4	34.4	47.5	61.6
3.0 cm	单链	4.1	7.6	10.4	13.3
?	双链	9.4	15.6	21.7	27.1
?	三链	13.2	23.3	31.1	40.7

粒子链旁开距离	?	粒子活度(mCi)
粒子链旁开距离	?	0.3	0.5	0.7	0.9
1 cm	单链	30.5	50.6	70.6	90.6
?	双链	69.2	114.3	161.7	207.2
?	三链	98.4	166.6	230.2	293.1
1.5 cm	单链	17.4	28.4	39.4	50.4
?	双链	36.1	60.4	84.3	107.6
?	三链	52.2	88.4	121.9	155.3
2.cm	单链	10.3	17.7	24.4	30.6
?	双链	21.9	36.4	50.5	65.2
?	三链	32.6	54.6	73.7	95.4
2.5 cm	单链	7.4	11.1	15.6	20.8
?	双链	14.4	23.5	32.6	41.1
?	三链	20.4	34.4	47.5	61.6
3.0 cm	单链	4.1	7.6	10.4	13.3
?	双链	9.4	15.6	21.7	27.1
?	三链	13.2	23.3	31.1	40.7

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