Dual energy coronary computed tomography angiography with low radiation dose-A feasibility study

doi:10.3877/cma.j.issn.2095-5782.2021.02.013

Abstract

Abstract:

Objective

To explore feasibility of dual energy coronary computed tomography angiography (DE-CCTA) with low radiation dose.

Methods

40 of 68 patients undergoing DE-CCTA were enrolled in this study prospectively and equally assigned to control group and experimental group randomly. The controlgroup (Group A, n = 20) were scanned using the conventional tube output and reconstructed using filtered back projection (FBP). The experimental group (Group B, n = 20) were scanned using the low radiation dose tube outputand reconstructed using sinogram affirmed iterative reconstruction (SAFIRE). Noise, signal to noise ratio (SNR) and contrast to noise ratio (CNR) of aortic root and myocardium, subjective scoring of left anterior descending branch (LAD) and myocardium, and radiation dose were measured and comparied between the two groups.

Results

Radiation dose of experimental group (4.68 ± 0.86) mSv was significantly lower than that of control group (6.69 ± 0.85) mSv (P < 0.05); Aortic and myocardial CNR were higher in experimental group (54.79 ± 10.35, 20.58 ± 4.04) than those in control group (43.66 ± 10.79, 16.93 ± 3.60) (all P < 0.05); Aortic and myocardial noise, SNR and subjective scoring were not statistically different between the two groups (all P > 0.05).

Conclutions

By combined using of low tube current, automatic current adjustment, minidose and iterative reconstruction (IR) technique, DE-CCTA could reduce radiation dose effectively with precondition of ensuring image quality of coronary artery and myocardium.

Key words: Tomography, X-ray computed, Dual-energy, Coronary artery, Myocardium, Radiation dose

Cunxue Pan, Hu Xiao, Jun Dang, Yuan Zhang, Xiaorui Wang, Wenya Liu. Dual energy coronary computed tomography angiography with low radiation dose-A feasibility study[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2021, 09(02): 188-193.

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URL: https://zhjrfsxdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-5782.2021.02.013

https://zhjrfsxdzzz.cma-cmc.com.cn/EN/Y2021/V09/I02/188

Figures/Tables 7

References 13

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组别	例数	BMI（kg/cm）	心率（次/min）	扫描范围（cm）
常规剂量组A组	20	24.12 ± 1.64	59.15 ± 5.28	130.48 ± 7.51
降剂量组B组	20	24.86 ± 1.80	57.00 ± 7.03	129.23 ± 15.8
统计量		-1.368	1.093	-0.054
P值		0.179	0.281	0.968

组别	例数	BMI（kg/cm）	心率（次/min）	扫描范围（cm）
常规剂量组A组	20	24.12 ± 1.64	59.15 ± 5.28	130.48 ± 7.51
降剂量组B组	20	24.86 ± 1.80	57.00 ± 7.03	129.23 ± 15.8
统计量		-1.368	1.093	-0.054
P值		0.179	0.281	0.968

组别	CTDIvol（mGy）	DLP（mGy×cm）	ED（mSv）
常规剂量组A组	31.54 ± 4.43	477.50 ± 60.80	6.69 ± 0.85
降剂量组B组	21.50 ± 4.76	333.95 ± 61.61	4.68 ± 0.86
t值	6.910	7.417	7.417
P值	0.000	0.000	0.000

组别	CTDIvol（mGy）	DLP（mGy×cm）	ED（mSv）
常规剂量组A组	31.54 ± 4.43	477.50 ± 60.80	6.69 ± 0.85
降剂量组B组	21.50 ± 4.76	333.95 ± 61.61	4.68 ± 0.86
t值	6.910	7.417	7.417
P值	0.000	0.000	0.000

组别	主动脉噪声（HU）	主动脉SNR	主动脉CNR
常规剂量组A组	18.59 ± 2.82	23.31 ± 4.75	43.66 ± 10.79
降剂量组B组	16.93 ± 2.90	24.75 ± 4.24	54.79 ± 10.35
t值	1.833	-1.010	-3.328
P值	0.075	0.319	0.002

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