Application of uterine artery embolization and methotrexate for conservative treatment of ectopic pregnancy

doi:10.3877/cma.j.issn.2095-5782.2014.04.007

Abstract

Abstract:

Objective

To evaluate and compare the value of uterine artery embolization (UAE) and UAE with methotrexate (MTX) chemotherapy in the treatment of ectopic pregnancy.

Methods

The clinical data of 34 patients with cervical pregnancy and cesarean scar pregnancy were retrospectively reviewed. The technique, clinical outcomes and complications of UAE and UAE along with the administration of MTX were evaluated.

Results

The fertility of all the patients were successfully preserved, and normal menses resumed within 1.0 to 4.5 months after UAE. The time to resolution of the serum β-hCG was not significantly different between the two groups (P>0.05). The duration of hospitalization was significantly longer in UAE+MTX group than in UAE group.

Conclusions

UAE with curettage is a saft and effective treatment for cervical and cesarean scar pregnancy.

Key words: Pregnancy, ectopic, Uterine artery, Chemoembolization, therapeutic, Curettage

Long Jin, Yuefeng Fan, Jian Gao, Lei Chen, Chen Chen, Shasha Cao. Application of uterine artery embolization and methotrexate for conservative treatment of ectopic pregnancy[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2014, 02(04): 22-25.

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URL: https://zhjrfsxdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-5782.2014.04.007

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Figures/Tables 2

References 9

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参数	UAE+MTX组(n=14)	UAE组(n=20)	P值
年龄(岁)	31.71±5.04	33.25±4.70	0.818
孕次	2.86±1.10	3.95±1.39	0.257
产次	0.79±0.80	0.95±0.22	0.001
流产次数	1.07±0.83	2.00±1.38	0.072
停经时间(天)	51.57±10.85	44.30±9.57	0.400
入院时血β-hCG水平(IU/L)	22614.29±25890.07	27319.67±30843.97	0.846
入院时检出胎心搏动例数	8	9	0.492
入院时阴道出血例数	12	15	0.454

参数	UAE+MTX组(n=14)	UAE组(n=20)	P值
年龄(岁)	31.71±5.04	33.25±4.70	0.818
孕次	2.86±1.10	3.95±1.39	0.257
产次	0.79±0.80	0.95±0.22	0.001
流产次数	1.07±0.83	2.00±1.38	0.072
停经时间(天)	51.57±10.85	44.30±9.57	0.400
入院时血β-hCG水平(IU/L)	22614.29±25890.07	27319.67±30843.97	0.846
入院时检出胎心搏动例数	8	9	0.492
入院时阴道出血例数	12	15	0.454

参数	UAE+MTX组(n=14)	UAE组(n=20)	P值
UAE后发热例数	4	4	0.487
UAE后恶心、呕吐例数	2	2	0.648
UAE后腹痛例数	5	5	0.418
刮宫术中出血(ml)	20.63±20.60(n=9)	15.56±14.34(n=19)	0.121
住院时间(天)	13.29±9.47	6.35±1.79	0.000
β-hCG恢复时间(天)	34.46±22.85	26.82±8.31	0.072
月经周期恢复时间(月)	2.38±1.00	1.81±0.52	0.141

参数	UAE+MTX组(n=14)	UAE组(n=20)	P值
UAE后发热例数	4	4	0.487
UAE后恶心、呕吐例数	2	2	0.648
UAE后腹痛例数	5	5	0.418
刮宫术中出血(ml)	20.63±20.60(n=9)	15.56±14.34(n=19)	0.121
住院时间(天)	13.29±9.47	6.35±1.79	0.000
β-hCG恢复时间(天)	34.46±22.85	26.82±8.31	0.072
月经周期恢复时间(月)	2.38±1.00	1.81±0.52	0.141

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