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中华介入放射学电子杂志 ›› 2023, Vol. 11 ›› Issue (01) : 55 -61. doi: 10.3877/cma.j.issn.2095-5782.2023.01.010

综述

结直肠癌肝转移非手术局部治疗进展及应用前景
李昊远1, 黄明1, 周劲梅1, 宋博涵1, 白锦峰1, 吴起杰1, 丁荣1,()   
  1. 1. 650118 云南昆明,云南省肿瘤医院(昆明医科大学第三附属医院)微创介入医学科
  • 收稿日期:2022-04-07 出版日期:2023-02-25
  • 通信作者: 丁荣
  • 基金资助:
    云南省科技厅科技计划项目(202305AD160013); 云南省科技厅科技计划项目(202101AY070001-66)

Progress in non-surgical local treatment of colorectal cancer liver metastases and its application prospects

Haoyuan Li1, Ming Huang1, Jinmei Zhou1, Bohan Song1, Jinfeng Bai1, Qijie Wu1, Rong Ding1,()   

  1. 1. Department of Minimally Invasive Interventional Medicine, the Third Affifiliated Hospital of Kunming Medical University, Tumor Hospital of Yunnan Province, Yunnan Kunming 650118, China
  • Received:2022-04-07 Published:2023-02-25
  • Corresponding author: Rong Ding
引用本文:

李昊远, 黄明, 周劲梅, 宋博涵, 白锦峰, 吴起杰, 丁荣. 结直肠癌肝转移非手术局部治疗进展及应用前景[J/OL]. 中华介入放射学电子杂志, 2023, 11(01): 55-61.

Haoyuan Li, Ming Huang, Jinmei Zhou, Bohan Song, Jinfeng Bai, Qijie Wu, Rong Ding. Progress in non-surgical local treatment of colorectal cancer liver metastases and its application prospects[J/OL]. Chinese Journal of Interventional Radiology(Electronic Edition), 2023, 11(01): 55-61.

肝脏是结直肠癌(colorectal cancer,CRC)最常见的转移部位,其恶性程度高、侵袭性强、预后差。约50%患者在病程中会出现肝脏转移,肝脏转移也是导致患者死亡的主要原因。手术切除仍是目前结直肠癌肝转移(colorectal cancer liver metastases,CRCLM)的主要治愈手段,但仅有不足20%患者能获得手术根治机会。因此,非手术局部治疗联合综合治疗至关重要。随着个体化治疗及多学科综合治疗协作组(multiple disciplinary team,MDT)诊治理念的提出,以及非手术局部治疗的迅速发展,结直肠癌肝转移患者的生存时间显著延长,甚至一部分初始不可手术切除患者通过非手术局部治疗成功转化后根治性切除。文章就近年来CRCLM非手术局部治疗的研究进展进行综述。

Liver is the most common site of metastasis for colorectal cancer (CRC), which is highly malignant, aggressive and has poor prognosis. About 50% of patients develop liver metastases during the course of the disease, and liver metastases are also a major cause of death. Surgical resection is still the main cure method for colorectal cancer liver metastases (CRCLM), but only less than 20% of patients have access to radical surgery. Therefore, non-surgical local treatment combined with comprehensive treatment is essential. With the concept of individualized treatment and Multiple disciplinary team (MDT), as well as the rapid development of non-surgical local treatment, the survival time of patients with liver metastases of colorectal cancer has been significantly prolonged, and even some patients with initial inoperable resection have been successfully converted to R0 resection through non-surgical local treatment. This article reviews the research progress on non-surgical local treatment of CRCLM in recent years.

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