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中华介入放射学电子杂志 ›› 2023, Vol. 11 ›› Issue (03) : 268 -274. doi: 10.3877/cma.j.issn.2095-5782.2023.03.013

综述

新型温敏性水凝胶在经导管动脉化疗栓塞中的应用进展
葛校永, 李亚华, 李宗明, 周子鹤, 吴昆鹏, 李一帆, 韩新巍, 任克伟()   
  1. 450052 河南郑州,郑州大学第一附属医院放射介入科;河南省肿瘤微创介入工程技术研究中心
  • 收稿日期:2023-02-08 出版日期:2023-08-25
  • 通信作者: 任克伟
  • 基金资助:
    河南省科技厅中原学者工作站资助项目(234400510027)

Application progress of novel temperature-sensitive hydrogel in transcatheter arterial chemoembolization

Xiaoyong Ge, Yahua Li, Zongming Li, Zihe Zhou, Kunpeng Wu, Yifan Li, Xinwei Han, Kewei Ren()   

  1. Department of Interventional Radiology, the First Affiliated Hospital of Zhengzhou University; Engineering Technology Research Center for Minimally Invasive Interventional Tumors of Henan Province, Henan Zhengzhou 450052, China
  • Received:2023-02-08 Published:2023-08-25
  • Corresponding author: Kewei Ren
引用本文:

葛校永, 李亚华, 李宗明, 周子鹤, 吴昆鹏, 李一帆, 韩新巍, 任克伟. 新型温敏性水凝胶在经导管动脉化疗栓塞中的应用进展[J]. 中华介入放射学电子杂志, 2023, 11(03): 268-274.

Xiaoyong Ge, Yahua Li, Zongming Li, Zihe Zhou, Kunpeng Wu, Yifan Li, Xinwei Han, Kewei Ren. Application progress of novel temperature-sensitive hydrogel in transcatheter arterial chemoembolization[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2023, 11(03): 268-274.

经导管动脉化疗栓塞术(transcatheter arterial chemoembolization,TACE)是目前抗肿瘤治疗常用的方法,手术的成功很大程度上依赖于栓塞剂的选择。温敏性水凝胶是一种具有特殊结构、温度刺激下的溶胶-凝胶相变及良好生物相容性的新型液体栓塞剂。文章就温敏性水凝胶的特点及其作为栓塞剂在TACE治疗中的应用进展进行系统总结和论述,并浅析了目前的挑战与前景。

Transcatheter arterial chemoembolization (TACE) is a currently common approach to antitumor therapy, in which procedural success depends heavily on the choice of embolic agent. Temperature-sensitive hydrogel is a novel liquid embolic agent with special structure, temperature-stimulated sol-gel phase transition and excellent biocompatibility. This review systematically summarized and discussed the characteristics of temperature-sensitive hydrogel and its application progress as embolic agent for TACE therapy, and briefly analyzed the existing challenges and prospects.

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