切换至 "中华医学电子期刊资源库"

中华介入放射学电子杂志 ›› 2019, Vol. 07 ›› Issue (03) : 231 -233. doi: 10.3877/cma.j.issn.2095-5782.2019.03.012

所属专题: 文献

非血管介入

介入治疗输卵管积水所致不孕的临床效果
曾庆红1, 王毅堂1,()   
  1. 1. 116037 大连市妇女儿童医疗中心血管瘤与介入科
  • 收稿日期:2019-06-23 出版日期:2019-08-01
  • 通信作者: 王毅堂
  • 基金资助:
    大连市医学科学研究计划项目(1711078)

Clinical effect of interventional treatment for infertility caused by hydrosalpinx

Qinghong Zeng1, Yitang Wang1,()   

  1. 1. Department of Hemangioma and Intervention, Dalian Municipal Women and Children Medical Center, Dalian 116037, China
  • Received:2019-06-23 Published:2019-08-01
  • Corresponding author: Yitang Wang
  • About author:
    Corresponding author: Wang Yitang, Email:
引用本文:

曾庆红, 王毅堂. 介入治疗输卵管积水所致不孕的临床效果[J/OL]. 中华介入放射学电子杂志, 2019, 07(03): 231-233.

Qinghong Zeng, Yitang Wang. Clinical effect of interventional treatment for infertility caused by hydrosalpinx[J/OL]. Chinese Journal of Interventional Radiology(Electronic Edition), 2019, 07(03): 231-233.

目的:

研究介入栓堵术治疗输卵管积水所致不孕的临床应用效果。

方法:

选择2016年10月至2018年10月大连市妇女儿童医疗中心收治的输卵管积水患者299例,其中169例行介入栓堵患者为研究A组,91例行常规手术治疗(腹腔镜下输卵管造口或者切除治疗)患者为研究B组,39例未治疗患者为对照组。比较三组患者的卵巢功能指标抗缪勒管激素(AMH)、着床率及异位妊娠率。

结果:

术前,三组AMH差异无统计学意义(P>0.05);术后,研究A组的AMH水平高于研究B组[(3.09±1.73)ng/ml vs.(2.69±2.03)ng/ml],差异有统计学意义(P=0.011),且研究A组术后的AMH水平高于术前[(3.09±1.73)ng/ml vs.(2.30±1.21)ng/ml],差异有统计学意义。研究A组的着床率为42.6%,显著高于研究B组(29.6%)和对照组(10.2%);研究A组的异位妊娠率为1.8%,低于研究B组(3.3%)和对照组(2.6%),差异均有统计学意义(P<0.05)。

结论:

对输卵管积水实施介入栓堵治疗,卵巢功能不受影响,着床率较高,异位妊娠率较低,操作技术可靠,值得临床推广应用。

Objective:

To study the clinical application effect of interventional embolization for the treatment of infertility caused by hydrosalpinx.

Methods:

A total of 299 patients with hydrosalpinx admitted to the Dalian Women and Children Medical Center from October 2016 to October 2018 were enrolled. Among them, 169 patients underwent interventional embolization for study group A and 91 patients underwent routine surgery (laparoscopic surgery) . Patients with tubal stoma or resection were studied in group B, and 39 untreated patients were in the control group. The ovarian function of anti-Mullerian hormone (AMH) , implantation rate and ectopic pregnancy rate were compared between the three groups.

Results:

There was no significant difference in AMH between the three groups before operation (P>0.05) . After operation, the AMH level in group A was higher than that in group B [ (3.09±1.73) ng/ml vs. (2.69±2.03) ng/ml], the difference was statistically significant (P=0.011) , and the AMH level in the study group A was higher than that before surgery [ (3.09±1.73) ng/ml vs. (2.30±1.21) ng/ml], the difference was statistically significant. The implantation rate of the study group A was 42.6%, which was significantly higher than that of the study group B (29.6%) and the control group (10.2%) . The ectopic pregnancy rate of the study group A was 1.8%, which was lower than that of the study group B (3.3%) . There was a statistically significant difference between the control group and the control group (2.6%) (P<0.05) .

Conclusions:

Interventional embolization for the treatment of hydrosalpinx, ovarian function is not affected, the implantation rate is higher, the ectopic pregnancy rate is lower, the operation technology is reliable, and it is worthy of clinical application.

表1 三组患者一般资料比较 (±s
表2 三组患者AMH水平比较 (±s
表3 三组患者的着床率及异位妊娠率比较 [例(%)]
[1]
中华医学会放射学分会介入专委会妇儿介入学组.子宫输卵管造影中国专家共识[J].中华介入放射学电子杂志,2018,6(3):185-187.
[2]
李楠,杜伯涛,李洋.小剂量阿司匹林在不孕症及辅助生殖技术中的应用[J].中国妇幼保健,2019,34(4):959-962.
[3]
陈明高,王丽华,张炎,等.输卵管积水不同处理方式对体外受精-胚胎移植结局的影响[J].介入放射学杂志,2018,27(12):1173-1176.
[4]
洪鑫,丁文彬,袁瑞凡,等.介入栓塞术治疗输卵管积水的效果[J].中国医学影像学杂志,2017,25(8):602-604.
[5]
王国贤,谭一清.输卵管栓堵研究进展[J].医学信息,2016,29(23):25-26.
[6]
Strandell A, Thorburn J, Hamberger L. Risk factors for ectopic pregnancy in assisted reproduction[J]. Fertil Steril,1999,71(2): 282-286.
[7]
郑晓红,赵晓丹,张淑玲,等.输卵管积水预处理方式对试管婴儿助孕结局的影响[J].医学理论与实践,2019,32(2): 178-180.
[8]
陈婷,苏迎春.子宫内膜微创刺激对不同人群妊娠结局影响的研究[J].生殖医学杂志,2018,27(12):1260-1265.
[9]
Zhou L, Li R, Wang R,et al. Local injury to the endometrium in controlled ovarian hyperstimulation cycles improves implantation rates[J]. Fertil Steril,2008,89(5): 1166-1176.
[10]
尹磊,秦占雄.输卵管介入术在不孕中的应用价值[J].云南医药,2017,38(1): 52-53.
[1] 陆婷, 范晴敏, 王洁, 万晓静, 许春芳, 董凤林. 超声引导下经皮穿刺置管引流对重症急性胰腺炎的疗效及应用时机的选择[J/OL]. 中华医学超声杂志(电子版), 2024, 21(05): 511-516.
[2] 王友芳, 李兴超, 刘清敏, 刘德彬, 刘松伍, 郭冬冬, 车峰远. 应激性高血糖指数对经皮冠状动脉介入术后急性心肌梗死患者发生主要不良心脑血管事件的预测价值[J/OL]. 中华危重症医学杂志(电子版), 2024, 17(02): 124-129.
[3] 李玉萍, 马会, 禹航. 腹腔镜下子宫动脉阻断术联合子宫肌瘤切除术治疗子宫肌瘤临床疗效[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(02): 238-244.
[4] 窦恩, 郑磊, 徐通海, 邓先锐. 局部神经阻滞麻醉在成人腹股沟疝无张力修补术中的应用[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(04): 442-445.
[5] 陈丽璇, 窦培宁, 肖扬. 干细胞治疗早发性卵巢功能不全的现状及未来展望[J/OL]. 中华细胞与干细胞杂志(电子版), 2024, 14(04): 239-248.
[6] 邢颖, 程石. 巨脾外科治疗现状与介入治疗序贯手术策略[J/OL]. 中华肝脏外科手术学电子杂志, 2024, 13(03): 253-258.
[7] 唐必英, 李钢. 治疗时机对动脉瘤性蛛网膜下腔出血患者预后的影响[J/OL]. 中华神经创伤外科电子杂志, 2024, 10(04): 213-219.
[8] 杨金朔, 吴桥伟, 王春雷, 史怀璋. 脑血管内支架成形术后再狭窄的研究进展[J/OL]. 中华神经创伤外科电子杂志, 2024, 10(03): 174-179.
[9] 牟超鹏, 宗斌, 刘奕, 史美英, 徐杜娟, 冯春光. 经远端桡动脉与经常规桡动脉行急诊冠脉介入诊疗后穿刺部位血肿的对比[J/OL]. 中华临床医师杂志(电子版), 2024, 18(03): 275-282.
[10] 陈芳, 王建英, 曹建用, 刘丽, 罗晓琴. 基于分析-设计-开发-实施-评价模式的叙事护理培训在产科预防性介入治疗中的应用[J/OL]. 中华介入放射学电子杂志, 2024, 12(04): 392-396.
[11] 李超迪, 刘娟芳, 闫肃, 秦胜东, 张镐哲, 常琼方, 韩新巍, 张建好. 血管性介入治疗在宫颈癌大出血患者中的临床疗效[J/OL]. 中华介入放射学电子杂志, 2024, 12(03): 217-220.
[12] 周宝林, 刘曦, 谌浩, 王金, 马雪琴. 温敏水凝胶在血管内栓塞治疗中的研究进展[J/OL]. 中华介入放射学电子杂志, 2024, 12(03): 244-249.
[13] 单兴华, 唐文栋, 赵仙先. 延伸导管在室间隔穿孔介入治疗的新应用一例[J/OL]. 中华心脏与心律电子杂志, 2024, 12(02): 126-128.
[14] 扈姝琴, 许红燕, 曹丹, 丁亚艳. 云平台视频管理在患儿重症哮喘中的应用及对应对方式的影响研究[J/OL]. 中华卫生应急电子杂志, 2024, 10(04): 218-223.
[15] 周洪千, 张煜坤, 顾天舒, 胡苏涛, 姜超, 张雪, 张昊, 陶华岳, 刘行, 刘彤, 陈康寅. 既往出血性脑卒中患者行经皮冠脉介入治疗后不良事件的危险因素分析[J/OL]. 中华脑血管病杂志(电子版), 2024, 18(04): 323-329.
阅读次数
全文


摘要