To explore the position and optimal pressure of blocking the superficial vein of lower extremities.

The bilateral lower limb veins of 12 healthy volunteers were selected for the study. Contrast-enhanced ultrasound was performed through the dorsalis pedis vein. Pneumatic cuffs were used to bind and apply pressure at 5 cm, 10 cm and 15 cm above the ankle joint. When the small saphenous vein (SSV) was not visible, the superficial vein blood flow of the lower extremities was effectively blocked and the pressure was recorded. In addition, the changes of diameter, flow velocity and blood flow of ipsilateral popliteal vein (POPV) before and after effective occlusion of superficial vein at 10cm of ankle were evaluated.

The pressure thresholds of supramalleolar 5 cm, 10 cm and 15 cm for effectively blocking the superficial veins of lower extremities were (66-69) mmHg, (68-71) mmHg and (73-75) mmHg (95% confidence interval), respectively. After effectively blocking the superficial veins of lower extremities at 10 cm on the ankle, the internal diameter and blood flow of ipsilateral POPV increased significantly (P<0.05), but the flow velocity did not increase significantly (P>0.05).

Different parts of the ankle require different pressure thresholds to effectively block the superficial veins of the lower extremities. CEUS can non-invasive monitor the blood flow of the superficial veins of the lower extremities effectively blocked by pneumatic tourniquet, which is helpful for the clinical treatment of deep venous thrombosis of the lower extremities.

To explore the application of ultrasound evaluation guidance in reducing the complications of radial artery puncture and catheterization.

The clinical data of 200 critically ill patients who were admitted to ICU underwent radial artery puncture was analyzed retrospectively from January 2018 to October 2019. 100 cases with routine puncture in 2018 were selected as the control group,and 100 cases with ultrasound-guided puncture in 2019 were introduced as the observation group. A retrospective analysis was performed to compare the complications during radial artery puncture and catheterization between the two groups, as well as the patients' satisfaction with nursing.

The puncture success rate of the observation group (ultrasound-guided puncture group) was significantly higher than that of the control group, the incidence of complications was significantly lower than that of the control group, and the patients' satisfaction with nursing was higher than that of the control group (P<0.05).

Ultrasound guidance can accurately assess the radial artery during puncture, accurately locate and guide the puncture, reduce the occurrence of complications, reduce pain, improve comfort and satisfaction of patients, improve the nurses' satisfaction and self-confidence, and make the operations more safer.

To analyze the relationship between NT-proBNP and SYNTAX score of STEMI patients.

The clinical data of STEMI patients (n=105) admitted to the Fifth Affiliated Hospital of Sun Yat-sen University from January 2019 to December 2019 were retrospectively analyzed. The SYNTAX scores were calculated according to CAG results for 105 STEMI patients who underwent percutaneous coronary intervention (PCI). All patients were divided into three groups ccording to the SYNTAX score: low-SS group, mid-SS group and high-SS group, and the relationship between NT-proBNP and SYNTAX score were evaluated.

The average age of 105 STEMI patients (92 male and 13 female) was 55.10±11.67 years (range29-84years). According to the SYNTAX score, there were 18 cases in low-SS group, 38 cases in mid-SS group, and 49 cases in thigh-SS group. There was no significant difference in the baseline clinical characteristic between three groups. But there were significant differences in LVEF, NT-proBNP, cTnI, AST, LDH, α-HBD, CK, CK-MB between three groups (P<0.05). The results of Pearson correlation analysis showed that NT-proBNP was positively correlated to SYNTAX (r=0.223, P=0.022).

The level of NT-proBNP is tightly related to cardiac function and can be taken into consideration for decision-making among PCI in STEMI patients.

To evaluate the diagnostic accuracy of coronary artery in-stent restenosis with 320 dynamic volume computed tomography in comparison of selective coronary angiography.

Two hundred and eight patients with suspected coronary artery in-stent restenosis underwent 320-DVCT coronary angiography, and selective coronary angiography was performed within 2 to 7 days subsequently.

The images acquired from 320-DVCT were excellent and sufficient enough to be used to evaluate coronary in -stent restenosis. For the stents with diameter of more than 3.0 mm, the image of optimization rate and success rate are significantly higher than those with a diameter of <3.0 mm. The sensitivity, specificity, positive and negative predictive value, rate of accuracy of 320-DVCT for detecting in-stent restenosis were 91.30%, 95.21%, 86.3%, 97.07% and 94.24%, respectively. The sensitivity, specificity, positive and negative predictive value, rate of accuracy of in-stent restenosis in the left anterior descending stent were 89.29%, 96.77%, 89.29%, 96.77% and 95.04%, respectively. The sensitivity, specificity, positive and negative predictive value, rate of accuracy of in-stent restenosis in the left circumflex stent were 88.89%, 92.73% , 80.00%, 96.23% and 91.78%, respectively. The sensitivity, specificity, positive and negative predictive value, rate of accuracy rate of in-stent restenosis in the right coronary artery stent were 88.00%, 94.92%, 88.00%, 94.92% and 92.86%, respectively.

320-DVCT angiography is a safe, noninvasive and effective method for the diagnosis of coronary in-stent restenosis at present.

To study the dose evaluation parameter and assess the therapeutic effect of prostate brachytherapy based on SPECT/CT detection.

A patient with prostate cancer underwent ¹²⁵I seed implantation was scanned by SPECT/CT. The images of SPECT and CT were fused and adjusted the radioactivity concentration region to match 145Gy and 217.5Gy isodose line. The two-radioactivity density count values were recorded. The relationship between target, the organ at risk and region in the two count value lines was observed. Counted the ratio between the volume in the two count value lines and the target volume. After 4 years follow up, the patient showed a good tumor control and no complication. Then, evaluated a second patient with the count value line and the ratio used before and followed up.

The count value matched 145Gy isodose line in the first patient was 200. The ratio between the volume in this count value line and target volume was 106%. A little part of the anterior wall of the rectum was involved. The count value matched 217.5Gy isodose line in the first patient was 300. The ratio between the volume in this count value line and target volume was 58%. The urethra was avoided. The 200-count value line in the second patient covered the target completely and part of the anterior wall of the rectum was involved. The ratio between the volume in this count value line and target volume was 176%. The 300-count value line in the second patient covered part of the urethra. The ratio between the volume in this count value line and target volume was 74%. The second patient was followed up for three months till now. PSA declined to normal and no complications of rectum and urethra were observed.

The dose distribution of ¹²⁵I seed in the prostate cancer can be detected and imaged by SPECT/CT. SPECT/CT based dose verification may be a new method to access the therapeutic effect of prostate cancer brachytherapy if the radioactive count value and the dose were related.

To explore the application value of intelligent mobile 3D navigation technology in hybrid operating room in endovascular treatment of proximal renal abdominal aortic aneurysm.

The clinical data of 7 patients with proximal renal abdominal aortic aneurysm treated in the hybrid operating room from February 2016 to June 2018 were retrospectively analyzed. During the operation, after 3D-DSA (digital subtraction angiography three-dimensional imaging) has been done, 3D reconstruction image and 2D (2D imaging) perspective image were fused, renal artery and other important branch blood vessels were marked in the process of operation. In addition, the intraoperative 3D navigation fusion images in different stages and positions were automatically modified. According to the requirements of the operation, the background density of blood vessels and bones in the fusion image should be improved, so the vascular visibility in the superimposed image were improved, and the stent release should be guided accurately. Therefore, the purpose of accurate navigation in the endovascular treatment is achieved.

The guidewire and catheter were successfully selected into the target vessel by the 3D navigation. Stents were all released accurately, and angiography indicated the aneurysms were successfully isolated without endoleak.

The openings of renal arteries and other vessel branches can be accurately marked by the three-dimensional navigation technology in the hybrid operating room, It is convenient to select target blood vessel during the operation. This technology plays an important role in guiding the endovascular treatment of proximal renal abdominal aortic aneurysm.

To compare the effects of different MRI sequences scanning on diagnostic grading and fat infiltration score of rotator cuff injury.

From January 2018 to January 2019, 100 patients diagnosed as rotator cuff injury clinically in our hospital were collected. The patients were imaged by different MRI combined sequences and scanning orientations to diagnose rotator cuff injury and to measure fat fraction.

The oblique coronal MRI had the highest detection rate on scapular sleeve injury, The oblique coronary SITR sequence showed the best for rotator cuff injury imaging (χ²=19.425, P<0.001) . The number of diagnosed cases of supraspinatus tendon injury (51 cases) , infraspinatus tendon (34 cases) , and subscapularis tendon (15 cases) imaged using oblique coronal MRI (SITR) were significantly higher than that using oblique coronal T₁WI (12, 28, 6 cases) or T₂WI (37, 19, 9 cases) . The preoperative fat infiltration score (2.58±0.23) in rotator cuff assess by oblique coronal MRI was significantly higher than that (1.72±0.17) during operation (t=7.320, P=0.002) .

The oblique coronal SITR sequence is superior to other sequences in the diagnosis and grading of rotator cuff injury and fat infiltration score. It has a high diagnostic rate for rotator cuff injury and is worth popularizing.

To explore the clinical effect of physiological and operative severity score for the enumeration of mortality and morbidity (POSSUM) score combined with acute physiology and chronic health evaluation (APACHE) II score on interventional therapy of lower extremity arteriosclerosis obliterans.

The clinical data of 48 patients with lower extremity arteriosclerosis obliterans treated with routine interventional therapy were retrospectively analyzed from May 2013 to April 2018 in our hospital, who were set up as A group, and the clinical data of 48 patients with lower extremity arteriosclerosis obliterans treated with interventional therapy on the guiding of preoperative POSSUM and APACHE II evaluation were retrospectively analyzed at the same period in our hospital, who were set up as B group. The success rate of interventional operation and hospitalization time of the 2 groups were compared, and the blood flow of posterior tibial artery and dorsal pedal artery and ankle brachial index (ABI) before and after treatment were compared, then the incidence of postoperative complications and the death situation were compared.

The success rate of operation in B group was significantly higher than that in A group (95.83% vs. 83.33%) , and the hospitalization time of B group was significantly shorter than that of A group[ (9.47±2.64) d vs. (14.56±3.28) d], with significantly statistical differences (χ²=4.019, t=8.375, both P<0.05) . The blood flow of posterior tibial artery and dorsal pedal artery of the 2 groups after treatment were significantly higher than those before treatment (P<0.05) , and those in B group after treatment were significantly higher than those of A group (P<0.05) . There was no significant difference in the ABI index before treatment between the 2 groups (P>0.05) , and those in the 2 groups after treatment were significantly higher than those before treatment (P<0.05) , and those in the B group after treatment was significantly higher than that of the A group[ (1.09±0.22) vs. (0.95±0.14) ], with a significantly statistical difference (t=3.785, P<0.05) . The incidence rate of postoperative total complications of the B group was lower than that of the A group (12.50% vs. 29.17%) , and the mortality rate of the B group was lower than that of the A group (0% vs. 8.33%) , with significantly statistical differences (both P<0.05) .

POSSUM score combined with APACHE II score guiding the interventional therapy of lower extremity arteriosclerosis obliterans can obviously improve the success rate of interventional operation, shorten the hospitalization time, improve the blood flow of lower limbs and ABI, and reduce the postoperative complications and death.

To evaluate the clinical effect of ¹²⁵I seed-strip stent implantation combined with transcatheter arterial chemoembolization in the treatment of malignant obstructive jaundice.

The clinical data of 120 cases with advanced malignant biliary obstructive jaundice, who lost the surgery chance or did not want to surgery in hospital, were randomly divided into three groups: biliary stent group (group A, n=40) , ¹²⁵I biliary stent group (group B, n=40) and ¹²⁵I biliary stent combined with transcatheter arterial chemoembolization group (group C, n=40) . The changes of total bilirubin (TBIL) , direct bilirubin (DBIL) and alkaline phosphatase (ALB) levels were observed and analyzed, and the mean biliary patency time and the survival time among three groups were evaluated.

Among three groups, the levels of TBIL, DBIL and ALB after 1 or 4 weeks were lower than before, the difference was statistically significant (P<0.01) . In group C, the mean biliary patency time and survival time were longer than those in groups A and B (P<0.05) . The mean survival time of groups A, B and C was (4.3±0.4) months, (5.9±0.6) months and (9.4±0.8) months, respectively, and the difference was statistically significant (F=6.897, P< 0.01) . The median survival time of group C was 14.6 months, which was significantly longer than that of groups A and B (6.1 and 9.8 months) , and the difference was statistically significant (Log-rank χ²=47.211, P< 0.05) .

A combination of ¹²⁵I biliary stent and transcatheter arterial chemoembolization can reduce jaundice, prolong the patency time of stent, and accordingly improve the quality of life of the patient after operation.

To compare the interventional curative effect of liver hemangioma patients with different types of blood supply treated by transcatheter arterial embolization (TAE) and portal vein interventional therapy.

From January 2008 to December 2013, 324 patients definitely diagnosed as liver hemangioma were retrospectively analyzed. The patients were classified by blood supply as follows: hypervascular (128 cases) , moderate (104 cases) , hypovascular (90 cases) and portal vein type (2 cases) . The first three groups were treated by TAE with the injection of pingyangmycin-lipiodol emulsion and gelatin sponge, while the patients in last group were treated by portal vein embolization. The drug dosage of different types of hemangioma during operation, change of tumor size and curative effect after different follow-up periods were comparatively analyzed.

The two portal vein cases were not involved in the statistical analysis. The dose of pingyangmycin-lipiodol emulsion was the highest in hypervascular type and moderate type was the following and the least was in hypovascular type. In the follow-up of 3 to 6 months, the changes in tumor size of each group were compared with one another. The reduction of tumor size was the most in hypervascular type, moderate type was following and the least is in hypovascular type. The tumor reduction of hypervascular type had no difference with that of the moderate type in the follow-ups of 6 to 12 months, 1 to 2 years and 2 to 3 years. However, the hypovascular type, with the least tumor reduction, had obvious difference from the first two groups in all follow-ups. The effective rates of hyper-and moderate blood supply types were up to 100% and were higher than those of hypovascular group 2 or 3 years after the treatment, with significant difference.

The curative effect of TAE for treatment of liver hemangioma has a obvious relationship with blood supply type that the hypervascular and moderate types were better than hypovascular type.

To observe the changes of iFlow parameters of ischemia reperfusion injury in rabbit hind limb skeletal muscle after acute ischemia using parametric digital subtraction angiography (DSA) color coding (syngo iFlow) and to explore the application in evaluating the ischemia-reperfusion injury of skeletal muscle.

Thirty New Zealand white rabbits were randomly divided into five groups, under 3 h of right hind limb ischemia followed by 0, 6, 12, and 24 h of reperfusion (IR groups, six rabbits were used for each reperfusion interval) , and six rabbits were served as Sham-operated control group. The rabbits in reperfusion groups accepted DSA scanning of double lower limbs and obtained the iFlow parameters (rPeak) by syngo iFlow software. Meanwhile, the serumal LDH, CK, MDA and SOD of the sample from jugular vein were measured, and the correlation between each iFlow parameter and serumal biochemical indicator was analyzed.

Compared with the control group, the serumal CK, LDH and MDA in IR groups increased (P<0.05) , while the value of SOD decreased with the extension duration of reperfusion (P<0.05) . Compared with the control group, the rPeak of IR groups decreased gradually with the prolongation of reperfusion (F=167.78, P<0.05) . The coefficients to correlation between rPeak and LDH, CK, MDA, SOD respectively were -0.885, -0.908, -0.541 and 0.832 (P<0.05) .

The correlation between iFlow parameters and serumal biochemical indicators are fairly good, and iFlow parameters can dynamically monitor the degree of ischemia reperfusion injury skeletal muscle.

To investigate the feasibility of microsurgery in hybrid operation room combined with 3D-DSA in treatment of cerebral aneurysms.

Fifty-six patients with cerebral aneurysms from February 2015 to December 2016 were retrospectively analyzed. Microsurgery and intra-operation 3D-DSA were carried out in this study.

Among the 56 patients, 3D-DSA showed aneurysm neck clipping and patency of the aneurysm artery in 43 cases (77%) . The residual neck of aneurysm was seen in 9 cases (16%) . After adjusting the clip, 8 cases were successfully clamped, one showed slight residual and no further adjustment was made. Four cases (7%) showed parent artery stenosis. After aneurysm clip adjustment, 2 cases had mild stenosis (lower than 20%) , not adjusted. During the operation, 13 patients (23%) were adjusted by 3D-DSA. One case bled again shortly after the operation and family members gave up. Postoperative intracranial infection occurred in 1 case. During the following 6~12 months, 1 patients died. Cerebral angiography showed no aneurysm recurrence and patency of the aneurysm artery in 55 cases.

The 3D-DSA technique in hybrid operation room can accurately evaluate the morphology and microsurgical clipping effect of the cerebral aneurysm in three-dimensional space, and plays great guidance role in the clipping of cerebral aneurysm.

To systematicly evaluate the efficacy and safety of transarterial embolization with drug-eluting beads of irinotecan (DEBIRI) for treatment of unresectable colorectal liver metastasis (CRLM) .

A comprehensive search of medical literature identified the studies describing the use of DEBIRI in treatment of CRLM. Data describing adverse events, pharmacokinetics, tumor response, and overall survival were collected.

Eight observational studies and two randomized controlled trials (RCTs) were reviewed. A total of 578 patients were included in the descriptive analysis of observational studies. Postembolization syndrome was the most common adverse event. Peak plasma levels of irinotecan were observed after 1~2 h of administration. Wide variations in tumor response were observed. The median survival time ranged from 5.4 months to 25 months. In the two RCTs, treatment with DEBIRI was superior to systemic chemotherapy with 5-fluorouracil/leucovorin/irinotecan in terms of overall response rate and progression-free survival.

For patients with unresectable CRLM, particularly after failure to respond to first-line regimens, DEBIRI represents a novel alternative to systemic chemotherapy alone or other local treatments.

To study various types of MRI imagings of cesarean scar pregnancy (CSP), and to evaluate their significance in clinical application. Also, the indications, efficacy and safety of methotrexate (MTX) combined with uterine curettage and uterine artery chemoembolization (UACE) combined with curettage in the treatment of different types of CSP were as well studied.

Clinical data of 187 patients with CSP treated in our hospital were retrospectively analyzed. They were divided into four groups according to different MRI types and treatments: Group A1 (CSPI patients treated by MTX combined with curettage), 45 patients; group B1( CSPI patients treated by UACE combined with curettage ), 12 patients; group A2 (CSPII patients treated by MTX combined with curettage), 40 patients; and group B2 (CSPII patients treated by UACE combined curettage), 90 patients. Their relative clinical data and follow-up results were statistically analyzed.

The blood loss during curettage showed no difference in both group A1 and group B1, while the number of patients with β-hCG decreased by more than 50% in the first day after curettage, and abnormal liver function rate, hysterectomy rate and treatment success rate all showed no significant difference. However, hospital stay in group A1 was much longer than in group B1, with significant difference. Group A2 and group B2 were seen a significant difference in blood loss during curettage, hospital stay, abnormal liver function rate, hysterectomy rate, decreased β-hCG decreased in the first day after curettage and treatment success rate.

MRI can not only diagnose CSP, but also can confirm its different types, thus, it has an important clinical significance for the treatment of CSP. UACE combined with curettage had better effect than MTX combined with curettage in the treatment of CSP patients, especially for CSPII patients, and it should be the first choice for the patients with CSPII.

To evaluate the safety and clinical short-term efficacy of interventional embolization with CalliSpheres-loaded microspheres in treating advanced hepatocellular carcinoma.

A total of 25 patients with advanced hepatocellular carcinoma underwent transcatheter arterial chemoembolization (TACE) plus using CalliSpheres-loaded microspheres treatment. The clinical and imaging data, complications of interventional treatment and prognosis were summarized and analyzed by modified response evaluation criteria in solid tumors (mRECIST); follow-up was performed on all patients.

The follow-up lasted 6 months. According to mRECIST, the 3-month objective response rate (CR+PR) was 80% and disease control rate (CR+PR+SD) was 88%; the 6-month objective response rate (CR+PR) was 72% and disease control rate (CR+PR+SD) was 80%. At day 3 after the procedure, the levels of ALT, AST and TBIL were increased, with a statistical significance compared with those before the operation. However, there was no significant difference in the level of albumin. At 3 months postoperatively, the indications of liver function returned to the normal level. And there was no significant difference between pre- and post-operation. No severe complications, such as bile leak with infection, liver abscess, abdominal hemorrhage, bleeding due to tumor rupture and gastrointestinal bleeding occurred in these patients.

TACE performed with CalliSpheres-loaded microspheres is a novel and safe option for patients with advanced hepatocellular carcinoma. Its clinical short-term efficacy was satisfied, yet its long-term efficacy needs further studies.

To discuss the CT findings after inferior vena cava(IVC) filter placement, and their value in evaluating the status of IVC filters after placement and related complications.

Pertinent data of 31 cases with IVC filter placement who underwent abdominal CT plain scan, contrast-enhanced scan and 3D reconstruction from January 2011 to May 2016 was collected for this study. The location, morphology and complications of IVC filters were evaluated on CT images.

(1) CT and 3D reconstruction images can clearly display the IVC filter and determine its type. Among the 31 cases, 12 cases of Ease type (including the retrievable Opt type) showed six-diamond shape, and 6 struts converging at the upper and lower apex of the filter formed the symmetric double baskets, with a retrieval hook in the bottom of OptEase filter; 7 cases of Vena Tech showed a cone shape formed by 6~8radial prongs, with vertical stabilizing struts around; 6 cases of Günther Tulip presented as inverted "tulip" shape, with a hook at the top and 4 struts below; 4 cases of Simon Nitinol presented as overlapping "umbrellas" , with 8 partially overlapping loops forming the top "umbrella" , and 6 diverging legs forming the lower "umbrella" ; 2 cases of temporary retrivable filter Tempofilter II showed long-arm "umbrella" shape, with 8 struts forming the cone-shaped basket, connected with long retrieval handle located in the course from internal jugular vein to inferior vena cava. (2) In 28 cases the filters were located in the infrarenal IVC, which was the conventional position, while 3 cases were in the suprarenal IVC, all of which formed suprarenal IVC thrombus before filter placement. (3) 10 cases showed obvious thrombus in the filters and above IVC, 1 of which also showed IVC stenosis, while no thrombus was found in the remaining 21 cases. (4) None of the 31 cases showed rupture of the main body or struts of IVC filters. 1filter migrated to the hepatic IVC and penetrated to liver parenchyma; the other 30 cases were classified into four grades according to IVC filter strut interactions with IVC wall. There were 7 cases classified as Grade 0, 13 cases as Grade 1, 3 cases as Grade 2, and 7 cases as Grade 3 (3 cases penetrating to the aortic wall and lumbar vertebrae, 1 case to the right psoas major and ileum, and 1 each to the aortic wall, anterior lumbar, and right diaphragmatic crura). The filters were significantly tilted in 7 cases, with the angle between the central longitudinal axis of the filter and the IVC being more than 15°, which showed the best result with coronal and sagittal reconstruction.

CT can clearly show the shapes, location and complications of IVC filters, which can provide a good way for retrieval of filters and treatment of complications.

To calculate the cerebral circulation time by subtract angiography of brain vascular in both normal people and patients with severe carotid artery stenosis, and evaluate its application in patients with severe carotid artery stenosis.

Thirty-six normal subjects’ cerebral circulation time was calculated by digital subtract angiography of brain vascular, and was compared with that of 24 severe carotid artery stenosis (rate of stenosis≥70%) patients by independent-samples t test.

The normal cerebral circulation time was (6.01±0.50) seconds while the patients cerebral circulation time was (6.60±0.56) seconds, which was statistically significant longer than that of normal subjects(t=4.264, P<0.05).

It is easy and accurate to measure the cerebral circulation time by digital subtract angiography, which can be an index for assessing cerebral perfusion. The cerebral circulation time of patients with severe carotid artery stenosis was longer than that of normal people, which indicates delayed blood supply.

To assess the value of diffusion weighted imaging in early response to target therapy of non-small-cell lung cancer.

32 patients with non-small-cell lung cancer were selected in this study. MRI imaging,DWI and contrast-enhanced CT were performed before and after the first cycle of target therapy. These patients were divided into responding and non-responding group according to the tumor maximum diameter shrinkage rate after the second cycle of target therapy. ADC value of the tumor and the tumor maximum diameter between two groups were compared. MRI combined with DWI and contrast-enhanced CT were also compared for the imaging effect of tumor and obstructive atelectasis.

There were no significantly statistical difference in tumor maximum diameter between pre-therapy and post-therapy in both groups(P>0.05). After the first cycle of target therapy,the mean ADC values increased significantly in responding group (×10^-3 mm²/s:1.48±0.23 vs. 1.23±0.21, t= -15.45, P<0.01) while it showed little change in non-responding group (×10^-3 mm²/s:1.20±0.27 vs. 1.15±0.32, t= -1.69, P>0.05). The increase rate of ADC value in responding group was considerably higher than that in non-responding group(%:17.7±5.7 vs. 4.6±2.1, t=6.72, P<0.01). There was also significantly statistical difference in imaging effect of tumor and obstructive atelectasis between MRI combined with DWI(13 cases 81.3%) and contrast-enhanced CT(6 cases, 37.5%)(P<0.05).

Compared to contrast-enhanced CT, MRI combined with DWI present the boundary of lung tumor and atelectasis more clearly and provide a better tool for the measurement of tumor size and the assessment of therapy effect. ADC value can be a promising biomarker for detecting target therapy responses at an early stage in non-small-cell lung cancer.

To evaluate the clinical characteristics of acute renal infarction and endovascular interventional therapy in treating acute renal infarction.

Since 2012 to 2014, 5 cases of renal artery occlusion were encountered in our hospital. Renal arterial suction and thrombolytic therapy were immediately carried out immediately after the diagnosis was confirmed.

Based on clinical manifestations, enhanced CT scan and angiography, the diagnosis of acute renal infarction was definitely confirmed in all 5 patients.1 patient underwent the medicine conservative treatment, the renal infarction did not change well at all; 4 patients underwent interventional therapy, and clinical symptoms relived with the blood flow in infracted area completely or partially returned to normal in 3 cases. The other 1 case lost the renal.

The early confirmation of diagnosis and prompt interventional therapy arecritical for rescue of the acute renal infarction.

This paper is to analyze the outcome and risk factors of interventional therapy for lower extremity deep venous thrombosis.

From July 2012 to June 2015, 65 patients (27 men and 38 women) underwent interventional therapy for deep venous thrombosis of lower extremity. 16 patients underwent conservative therapy, 23 patients underwent catheter-directed thrombolysis, 26 patients underwent mechanical thrombolysis plus catheter-directed thrombolysis.

Follow up duration are 1 to 30 months. During the follow up duration, 13 patients replase or fail treated, the cured rate was 80.0%. The average hospitalization time is 16.2 d.The result of single factor study and logistic regression analysis show that the treatment methods and the stages of thrombosis are the prognosis factors. Multivariate multiple linear regression analysis show that the stages and location of thrombosis, and the filter influence the duration of hospitalization.

The treatment methods and the stages of thrombosis influence the prognosis of DVT with thrombolysis therapy. The stages ,locations of thrombosis and the filter will influence the duration of hospitalization.