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Chinese Journal of Interventional Radiology(Electronic Edition) ›› 2025, Vol. 13 ›› Issue (01): 7-13. doi: 10.3877/cma.j.issn.2095-5782.2025.01.002

• Monographic Study·Respiratory Intervention • Previous Articles    

Rapid on-site evaluation technology and its application advancements in interventional pulmonology

Zhiruo Zhu1, Yaohui Wang2,3,4,5, Yun Xiao2,3,4,5, Rui Zhou2,3,4,5, Kui Xiao2,3,4,5,()   

  1. 1. Department of Pulmonary and Critical Care Medicine,the Fourth Hospital of Changsha,Hunan Changsha 410006
    2. Department of Pulmonary and Critical Care Medicine,the Second Xiangya Hospital,Central South University
    3. Research Unit of Respiratory Disease,Central South University
    4. Clinical Medical Research Center for Resipratory and Critical Care Medicine of Hunan Province
    5. Diagnosis and Treatment Center of Respiratory Disease,Central South University,Hunan Changsha 410011,China
  • Received:2024-03-12 Online:2025-02-25 Published:2025-04-02
  • Contact: Kui Xiao

Abstract:

Rapid on-site evaluation (ROSE) technology is a real-time pathological technique that involves rapid staining and microscopic observation of biopsy or brush specimens at the sampling site, followed by on-site evaluation and judgment by expert to obtain preliminary diagnosis.Based on the preliminary ROSE diagnosis, priority strategies can be formulated to provide feedback and guide the next step of operation.With the rapid development of endoscopic technology and fine needle aspiration technology, ROSE technology which can quickly stain and observe biopsy specimens on site has also flourished, especially in interventional pulmonology.The application of ROSE in interventional pulmonology diagnosis and treatment mainly involve the combination of transbronchial needle aspiration (TBNA),transbronchial lung biopsy (TBLB), endobronchial ultrasound guided transbronchial needle aspiration(EBUS-TBNA), endobronchial ultrasonography with guide sheath transbronchus lung biopsy (EBUS-GSTBLB) and other bronchoscopic procedures.Other applications of ROSE in interventional pulmonology include percutaneous lung biopsy and medical thoracoscopy.This review specifically elaborate on the origin, development, classification, operational process, and recent advances of ROSE technology in interventional pulmonology.

Key words: Rapid on-site evaluation, ROSE, Interventional pulmonology

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