The value of rapid on-site evaluation applied in the bronchoscopic intervention for diagnosis of thoracic neoplasms

doi:10.3877/cma.j.issn.2095-5782.2021.03.012

Chinese Journal of Interventional Radiology(Electronic Edition) ›› 2021, Vol. 09 ›› Issue (03): 307-312. doi: 10.3877/cma.j.issn.2095-5782.2021.03.012

• Non-vascular Intervention • Previous Articles Next Articles

The value of rapid on-site evaluation applied in the bronchoscopic intervention for diagnosis of thoracic neoplasms

Liwei Wang¹, Yin Li²^,^†(), Lianghong Wan², Yunchao Huang³, Hui Tan³, Zaoxiu Hu⁴, Qiubo Huang³, Min Tian⁵

^1. Department of Ultrasound Medicine, the Third Affiliated Hospital of Kunming Medical University (Yunnan Cancer Hospital, Yunnan Cancer Center), Yunnan Kunming 650118
^2. Thoracic Surgery and Tumor Department, Fuyuan County People's Hospital (the Third Affiliated Hospital of Kunming Medical University Union Hospital), Yunnan Qujing 655000
^3. Department of Thoracic Surgery I, the Third Affiliated Hospital of Kunming Medical University (Yunnan Cancer Hospital, Yunnan Cancer Center), Yunnan Kunming 650118
^4. Pathology Department, the Third Affiliated Hospital of Kunming Medical University (Yunnan Cancer Hospital, Yunnan Cancer Center), Yunnan Kunming 650118
^5. Department of Vascular Surgery, Yanan Hospital of Kunming City, Yunnan Kunming 650051, China

Received:2020-12-19 Online:2021-08-25 Published:2021-09-27
Contact: Yin Li

Abstract

Abstract:

Objective

To explored the value and safety of rapid on-site evaluation (ROSE) applied in bronchoscopic intervention for diagnosis of thoracic neoplasms.

Methods

The clinical data of 635 patients with thoracic neoplasms underwent bronchoscopic intervention diagnosis and ROSE in the Yunnan Tumor Hospital from October 2019 to October 2020 were retrospectively analyzed. All patients were confirmed by CT or PET/CT with pulmonary lesions or at least 1 set of mediastinal or hilar lymph nodes enlargement.

Results

All patients successfully completed the biopsy operation. The complication rates were 14.9% (96/635), and there were no serious complications. The coherence of ROSE and HE staining was 93.7% (594/635). Among 485 cases of malignant diagnosis, the false negative rate of ROSE was 2.4% (15/635), and there were no false positive results. The whole group of lung neoplasms were performed 1 785 times biopsies at 680 sites, withan average of (2.6 ± 1.9) per site. The successful rate of biopsies was 89.3% (319/357). Mediastinal lymph nodes were punctured at 435 sites for 865 times with an average of (2.0 ± 0.4) punctures per site. The successful rate was 82.1% (710/865). Among 70 patients with suspected malignant by HE staining in the first non-ROSE examination, 55 cases got confirmed malignant diagnoses by ROSE examination, and the effective rate was 78.5% (55/70).

Conclusions

ROSE applied in the bronchoscopic intervention for diagnosis of thoracic neoplasms has good concordance with HE staining in the diagnosis. ROSE has a high biopsy success rate, could effectively reduce the recheck rate, and is easy to operate, safe and reliable. ROSE is worthy of clinical application.

Key words: Rapid on-site evaluation, Thoracic neoplasms, Bronchoscopic intervention diagnosis

Liwei Wang, Yin Li, Lianghong Wan, Yunchao Huang, Hui Tan, Zaoxiu Hu, Qiubo Huang, Min Tian. The value of rapid on-site evaluation applied in the bronchoscopic intervention for diagnosis of thoracic neoplasms[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2021, 09(03): 307-312.

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