Application value of X-ray stereotactic vacuum-assisted biopsy for suspected breast calcification

doi:10.3877/cma.j.issn.2095-5782.2021.03.011

Abstract

Abstract:

Objective

To explore the application value of stereotactic vacuum-assisted biopsy (SVAB) in the diagnosis and treatment of suspicious breast calcification.

Methods

From December 2015 to December 2019, female patients who underwent X-ray stereotactic biopsy due to suspicious breast calcification in Hong Kong-Shenzhen Hospital,were selected as subjects to evaluate the efficacy, safety and underestimation rate of this biopsy method.

Results

A total of 558 biopsies were completed successfully in 518 patients (40 bilateral cases). Surgical pathology showed malignant lesions in 74 cases (59 cases of ductal carcinoma in situ, 7 cases of ductal carcinoma in situ with focal invasive carcinoma, 7 cases of invasive ductal carcinoma, and 1 case of invasive micropapillary carcinoma), atypical ductal hyperplasia in 45 cases, and benign lesions in 439 cases. Pathologically underrated rates were 6.8% (4/59) for ductal carcinoma in situ and 2.2% (1/45) for atypical ductal hyperplasia.

Conclusions

SVAB is safe and accurate for the location and biopsy of suspicious breast calcification, and plays an important role in the preoperative diagnosis of early breast cancer with unclear clinical manifestations.

Key words: X-ray stereotactic vacuum-assisted biopsy, Breast calcification, Breast cancer

Jian Shi, Jiannan Wei, Shengguang Zeng, Jianlong He, Na Xie, Aiqiu Zheng, Yong Yang. Application value of X-ray stereotactic vacuum-assisted biopsy for suspected breast calcification[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2021, 09(03): 300-306.

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Figures/Tables 6

References 18

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年龄分组		良性病变		恶性病变			P值
		其他良性	ADH	原位癌	浸润性癌	PPV（%）
		439	45	59	15	PPV（%）
≤ 39		102	7	10	1	9.2（11/120）
40~49		251	22	32	6	12.2（38/311）
50~59		80	11	12	6	16.5（18/109）
≥ 60		6	5	5	2	38.9（7/18）	0.009
BI-RADS分级
	4a	363	32	42	4	10.4（46/441）
	4b	71	10	11	7	18.2（18/99）
	4c	5	3	5	4	52.9（9/17）
	5	0	0	1	0	100（1/1）	0.000
钙化形态
	无定形	234	27	21	10	10.6（31/292）
	粗糙不均质	16	2	5	1	25.0（6/24）
	细小多形性	178	13	24	3	12.4（27/218）
	细线样或细小分枝样	11	3	9	1	41.6（10/24）	0.000
钙化分布情况
	簇状	337	31	45	7	12.4（52/420）
	线样	2	0	3	1	66.7（4/6）
	节段样	29	6	7	2	20.5（9/44）
	区域性	67	7	4	4	9.4（8/82）
	弥漫性	4	1	0	1	16.7（1/6）	0.006

年龄分组		良性病变		恶性病变			P值
		其他良性	ADH	原位癌	浸润性癌	PPV（%）
		439	45	59	15	PPV（%）
≤ 39		102	7	10	1	9.2（11/120）
40~49		251	22	32	6	12.2（38/311）
50~59		80	11	12	6	16.5（18/109）
≥ 60		6	5	5	2	38.9（7/18）	0.009
BI-RADS分级
	4a	363	32	42	4	10.4（46/441）
	4b	71	10	11	7	18.2（18/99）
	4c	5	3	5	4	52.9（9/17）
	5	0	0	1	0	100（1/1）	0.000
钙化形态
	无定形	234	27	21	10	10.6（31/292）
	粗糙不均质	16	2	5	1	25.0（6/24）
	细小多形性	178	13	24	3	12.4（27/218）
	细线样或细小分枝样	11	3	9	1	41.6（10/24）	0.000
钙化分布情况
	簇状	337	31	45	7	12.4（52/420）
	线样	2	0	3	1	66.7（4/6）
	节段样	29	6	7	2	20.5（9/44）
	区域性	67	7	4	4	9.4（8/82）
	弥漫性	4	1	0	1	16.7（1/6）	0.006

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