To observe and investigate the clinical effect of artery scleroembolization in treatment of hemangioma combined with Kasabach-Merritt phenomenon (KMP) , and to provide experience and reference for the diagnosis and treatment of such disease.

Thirteen patients with hemangioma in children with KMP in Beijing Children's Hospital from August 2015 to March 2017 were seleted and treated with arterial embolization using emulsion and microspheres (consisting of bleomycin+lipiodol+dexamethasone+contrast agent) or bleomycin mixed microspheres as emboliaztion agents. The clinical effect and examination indexes were observed and compared before and after treatment.

All the 13 patients treated with arterial embolization were cured (11 cases) or improved (2 cases) . The average of platelet count, fibrinogen and tumor size before and after operation were respectively changed from (34.62±29.97) ×10⁹/L to (212.08±70.10) ×10⁹/L, (1.06±0.45) g/L to (2.10±0.66) g/L and (74.04±57.51) cm³ to (46.94±42.52) cm³, and the differences were significant (t values were 5.074, 8.474 and 4.985, P<0.01) . Two cases reached the standard of surgery and completed the tumor resection.

Arterial embolization therapy is a significant, safe and reproducible therapeutic method on hemangioma and coagulation dysfunction. Based on experiences from operations, it is recommended that preoperative enhanced CT which is carefully evaluated, soft puncture guided by ultrasound, appropriate embolic material and local injection, sclerotherapy, etc. should be used to increase the achievement ratio.