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Chinese Journal of Interventional Radiology(Electronic Edition) ›› 2023, Vol. 11 ›› Issue (01): 6-11. doi: 10.3877/cma.j.issn.2095-5782.2023.01.002

• Vascular Intervention • Previous Articles     Next Articles

A preliminary study on interventional treatment methods and therapeutic effects for hepatic hemangioma in children

Jie Yin1, Chi Wang2, Yue Liu1,(), Yanhua Li1   

  1. 1. Department of Radiology, Beijing Children's Hospital, Capital Medical University, MOE Key Laboratory of Major Diseases in Children; National Center for Children's Health, Beijing 100045
    2. Department of Radiology, Children's Hospital, Capital Institute of Pediatrics, Beijing 100020, China
  • Received:2022-04-15 Online:2023-02-25 Published:2023-03-15
  • Contact: Yue Liu

Abstract:

Objective

To explore interventional treatment methods and therapeutic effects of interventional therapy for hepatic hemangioma in children.

Methods

The clinical data of 31 children underwent interventional therapy for hepatic hemangioma in Beijing Children's Hospital from January 2016 to January 2019 were retrospectively analyzed. The patients are ranging in age from 6 days to 9 years old. Including 26 cases of congenital hepatic hemangiomas, 5 cases of infantile hepatic hemangiomas, and imaging examination showed 5 cases of multiple liver lesions and 26 cases of single liver lesions. All children received plain CT scan, enhanced CT scan and embolization sclerotherapy for hepatic hemangioma. CT findings before and after interventional embolization were used to analyze the efficacy of embolization sclerotherapy for hepatic hemangioma in different types of children. The paired sample t test was used to compare the volume differences of the infantile and congenital hemangioma lesions before and after interventional therapy.

Results

23 cases received single interventional therapy, 6 received two interventional therapy, and2 received three interventional therapy. 26 cases in total 31 patients were followed up, including 23 congenital hepatic hemangioma and 3 infant hepatic hemangioma. The tumors disappeared completely in 11 children and the children recovered completely, while the tumors were partially reduced in 15 children (4 cases reduced by more than 70%, the effect was significant; 6 cases reduced by 30%~50%, partially effective; 5 cases reduced less than 30%, the effect was not obvious). The mean preoperative and postoperative volumes of congenital hemangioma were (161.86 ± 21.40) cm3 and (41.46 ± 9.73) cm3, and the mean preoperative and postoperative volumes of infantile hemangioma were (22.73 ± 1.92) cm3 and (11.18 ± 3.18) cm3. The preoperative and postoperative volume differences for congenital hemangioma and infantile hemangioma were all statistically significant (P < 0.001).

Conclusions

Embolization sclerotherapy of hepatic hemangioma is a safe and effective minimally invasive treatment for hepatic hemangioma in children,and preoperative classification is an important factor in the efficacy of interventional therapy for pediatric hepatic hemangioma in children.

Key words: Children, Hepatic hemangioma, Interventional therapy

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