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Chinese Journal of Interventional Radiology(Electronic Edition) ›› 2021, Vol. 09 ›› Issue (01): 41-44. doi: 10.3877/cma.j.issn.2095-5782.2021.01.007

Special Issue:

• Vascular Intervention • Previous Articles     Next Articles

Clinical study on sclerotherapy with polidocanol injectable foam in treatment of Puig's Ⅰ and Ⅱ perianal venous malformations in children

Song Zuo1, Changxian Dong1,(), Li Xiao1, Yanlin Wang1, Xiaonan Guo1, Tengfei Ren1   

  1. 1. Department of Hemangioma and Vascular Malformation, Henan Provincial People's Hospital; People's Hospital of Zhengzhou University, Henan Zhengzhou 450003, China.
  • Received:2020-09-22 Online:2021-02-25 Published:2021-02-25
  • Contact: Changxian Dong

Abstract:

Objective

To evaluate the clinical efficacy of DSA-guided sclerotherapy with polidocanol injectable foam in treatment of Puig's Ⅰ and Ⅱ perianal venous malformations in children.

Methods

A retrospective analysis was made of 38 children with Puig's Ⅰ and Ⅱ perianal venous malformations who were treated with DSA-guided percutaneous puncture of 3% polydocarol foam sclerotherapy under general anesthesia from March 2018 to June 2019 in Henan Provincial People's hospital.The curative effect, adverse reactions were observed in follow-up.

Results

The 38 children were treated 76 times (1-3 times/case), and the average single application dose of 3% polydocarol foam sclerosant was (5.94±1.69) mL. 28 cases were cured, 9 cases were basically cured and 1 case was effective; the cure rate was 73.68% (28/38), and the total effective rate was 100%. Adverse reactions. There were mild swelling at the lesion in 76 cases after interventional sclerotherapy and tension blisters in the skin in 3 cases.One patient had mild skin ulceration, however, the ulcertion healed after 10 days of symptomatic treatment. After 14-28 months of follow-up (median follow-up time was 24 months), there was no significant recurrence of symptoms.

Conclusions

3% polydocanol foam sclerotherapy is a minimally invasive, safe, effective and worth popularization treatment for Puig's Ⅰ and Ⅱ perianal venous malformations in children.

Key words: Venous malformation, Children, Polydocanol, Sclerotherapy

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