To investigate the safety and efficacy of abdominal aortic balloon occlusion combined with cesarean section in the treatment of pernicious placenta previa, and to evaluate its impact on the reproductive function and neonatal health.

The clinical data of 1 018 patients with pernicious placenta previa admitted to our hospital from January 2013 to January 2019 were retrospectively analyzed. All patients received abdominal aortic balloon occlusion combined with cesarean section. The purpose of this study was to evaluate the safety and efficacy of abdominal aortic balloon occlusion combined with cesarean section in the treatment of dangerous placenta previa by analyzing the operation time, intraoperative blood loss, blood transfusion, intraoperative and postoperative complications, postoperative recovery, fetal radiation exposure time and dose, and neonatal Apgar score in 1 018 cases.

Among all the 1 018 patients, 940 patients received only abdominal aortic balloon occlusion, 78 patients underwent uterine artery embolization due to postoperative bleeding. All patients successfully preserved the uterus. Except for 8 cases of right femoral artery thrombosis and 3 cases of right lower limb intermuscular venous thrombosis, the remaining patients did not have postoperative lower limb arteriovenous thrombosis, renal insufficiency, late postpartum hemorrhage, ectopic embolism, spinal cord or peripheral nerve damage or pelvic infection or other serious complications. The mean operation time was (57.6 ± 17.3) min. The average intraoperative blood loss was (590 ± 570)mL . One hundred and twenty-six patients (12.38%, 126/1018) were given blood transfusion, with an average of (630 ± 450) mL. The average hospital stay was (6.4 ± 4.2) d, the average fetal radiation exposure time was (5.1 ± 1.4) s, and the average dose was (4.0 ± 2.6) mGy in 1018 cases. Neonatal Apgar scores were (9.2 ± 0.4) at 1 min and (9.6 ± 0.3) at 5 min. During follow-up until May 31, 2019, 38 cases were lost to follow-up, 137 were in lactation, and 843 had recurrent menstruation. Except for 38 cases lost to follow-up, the remaining 982 surviving newborns (including 2 twins) showed no abnormalities in the 42-days postnatal outpatient follow-up examination.

Balloon occlusion of abdominal aorta combined with cesarean section is a safe and effective method for the treatment of pernicious placenta previa,which can reduce the risk of hysterectomy, decrease intraoperative blood loss, and have no adverse effects on pregnant women or newborns.