Analysis of clinical effect and prognostic factors of oculomotor nerve palsy induced by posterior communicating artery aneurysms after endovascular embolization

doi:10.3877/cma.j.issn.2095-5782.2020.02.010

Abstract

Abstract:

Objective

To explore and analyze the clinical effects and prognostic factors of oculomotor nerve palsy (ONP) induced by posterior communicating artery (PComA) aneurysms after endovascular embolization.

Methods

The clinical data and follow-up data of 57 patients with PComA aneurysmal ONP who underwent endovascular embolization in our department from April 2010 to October 2018 were retrospectively analyzed. According to the degree of postoperative recovery, they were divided into a cured (complete recovery) group and a non-cured (partial recovery + no recovery) group. The relevant data of the two groups of patients were analyzed and compared.

Results

Among 57 patients, 42 patients recovered completely, 13 patients recovered partially, and 2 patients did not recover. The degree of paralysis before surgery (73.8% vs 26.7%, P=0.002) and whether there was a subarachnoid hemorrhage (54.8% vs 20%, P=0.033) was statistically significant differences.

Conclusions

Endovascular embolization therapy can promote the recovery of symptoms in patients with PComA aneurysmal ONP. The symptoms of ONP patients with mild preoperative paralysis and subarachnoid hemorrhage are more easily recovered after endovascular embolization.

Key words: Posterior communicating artery aneurysm, Oculomotor nerve palsy, Endovascular embolization, Prognostic factor

Feilong Zhao, Bin Wang, Qingquan Zu, Linbo Zhao, Zhenyu Jia, Haibin Shi, Sheng Liu. Analysis of clinical effect and prognostic factors of oculomotor nerve palsy induced by posterior communicating artery aneurysms after endovascular embolization[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2020, 08(02): 151-154.

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References 14

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?		治愈组n=42	非治愈组n=15	t/χ²值	P值
年龄		61±11	61±8	-0.157	0.876
性别		?	?	0.529	0.599
?	男	3	2	?	?
?	女	39	13	?	?
高血压史		?	?	0.000	1.000
?	有	20	7	?	?
?	无	22	8	?	?
蛛网膜下腔出血		?	?	5.384	0.003
?	有	20	3	?	?
?	无	22	12	?	?
术前麻痹时间		?	?	2.619	0.106
?	<2周	34	9	?	?
?	≥2周	8	6	?	?
术前麻痹程度		?	?	10.365	0.002
?	完全性	11	12	?	?
?	部分性	31	3	?	?
动脉瘤大小		?	?	3.040	0.081
?	≤7 mm	8	7	?	?
?	>7 mm	34	8	?	?
是否为宽颈动脉瘤		?	?	0.000	1.000
?	是	30	11	?	?
?	否	12	4	?	?

?		治愈组n=42	非治愈组n=15	t/χ²值	P值
年龄		61±11	61±8	-0.157	0.876
性别		?	?	0.529	0.599
?	男	3	2	?	?
?	女	39	13	?	?
高血压史		?	?	0.000	1.000
?	有	20	7	?	?
?	无	22	8	?	?
蛛网膜下腔出血		?	?	5.384	0.003
?	有	20	3	?	?
?	无	22	12	?	?
术前麻痹时间		?	?	2.619	0.106
?	<2周	34	9	?	?
?	≥2周	8	6	?	?
术前麻痹程度		?	?	10.365	0.002
?	完全性	11	12	?	?
?	部分性	31	3	?	?
动脉瘤大小		?	?	3.040	0.081
?	≤7 mm	8	7	?	?
?	>7 mm	34	8	?	?
是否为宽颈动脉瘤		?	?	0.000	1.000
?	是	30	11	?	?
?	否	12	4	?	?

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