To explore the efficacy of CT guided local injection of methylprednisolone in the treatment of percutaneous punctured bone eosinophilic granuloma.

A total of 15 cases of bone eosinophilic granuloma underwent CT guided percutaneous puncture biopsy from September 2009 to July 2016 in our hospital. With pathologically confirmed diagnosis, these patients received local injection of methylprednisolone sodium succinate therapy. The outcomes were followed up and evaluated based on the Neer and Chigira healing evaluation standard.

After 1 month of the treatment, the destructed bone area shrunk, the bone cortex became thicker; 4-6 months after the treatment, most of the destructed bone area was repaired and the cortical bone restored harder. Patients with local pain got significant relieved or even the pain disappeared after the treatment. There were no serious complications in the process of puncture and postoperative pain. 6 months after operation, 6 cases of grade II, 3 cases of grade III, 6 cases of grade IV, 12 months after operation, 5 cases of grade III, 10 cases of grade IV. The patients were followed up for 3 months to 6 years. The average follow-up time was 30 months. The results showed that the lesions were obviously repaired, and no recurrence was found. No serious complication occurred.

CT guided percutaneous puncture and local injection of methylprednisolone sodium succinate is a safe, accurate and minimally invasive strategy for treating eosinophilic granuloma of the bone. The procedure brings up less complications with better outcome, thus, is worthy of clinical application.