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中华介入放射学电子杂志 ›› 2021, Vol. 09 ›› Issue (04) : 423 -428. doi: 10.3877/cma.j.issn.2095-5782.2021.04.014

影像诊断

评估前列腺癌患者的前列腺动脉造影表现
田伟1, 徐忠伟1, 周春高1, 冷斌1, 施海彬1, 刘圣1,()   
  1. 1. 210029 江苏南京,南京医科大学第一附属医院介入放射科
  • 收稿日期:2021-08-25 出版日期:2021-11-25
  • 通信作者: 刘圣

Angiography findings in patients with prostate cancer during prostatic artery embolization

Wei Tian1, Zhongwei Xu1, Chungao Zhou1, Bing Leng1, Haibin Shi1, Sheng Liu1,()   

  1. 1. Department of Interventional Radiology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Nanjing 210029, China
  • Received:2021-08-25 Published:2021-11-25
  • Corresponding author: Sheng Liu
引用本文:

田伟, 徐忠伟, 周春高, 冷斌, 施海彬, 刘圣. 评估前列腺癌患者的前列腺动脉造影表现[J/OL]. 中华介入放射学电子杂志, 2021, 09(04): 423-428.

Wei Tian, Zhongwei Xu, Chungao Zhou, Bing Leng, Haibin Shi, Sheng Liu. Angiography findings in patients with prostate cancer during prostatic artery embolization[J/OL]. Chinese Journal of Interventional Radiology(Electronic Edition), 2021, 09(04): 423-428.

目的

探讨前列腺癌患者的前列腺动脉造影表现。

方法

回顾性分析2014年10月至2019年12月经活检证实前列腺癌并接受PAE治疗患者的血管造影表现。观察前列腺动脉(PA)数目、起源以及异常造影表现,通过国际前列腺症状评分(IPSS),生活质量(QoL)和并发症等指标评估造影异常患者PAE治疗前列腺癌源性下尿路梗阻或血尿的疗效。

结果

61例患者完成121侧盆腔造影(1侧盆腔由于髂内动脉闭塞未行造影),共显影147支PAs。PA起源包括阴部内动脉(46例,31.3%),膀胱动脉(40例,27.3%),闭孔动脉(31例,21.1%),臀-阴动脉干(23例,15.7%),臀下动脉(3例,2.0%),阴部副动脉(3例,2.0%)和臀上动脉(1例,0.6%)。6例患者髂内动脉造影可见动静脉瘘,但术前及术后随访时间点IPSS、QoL评分差异均有统计学意义(P值均< 0.05)。所有患者术后随访均未出现盆腔脏器缺血坏死等严重并发症。

结论

前列腺癌患者的PA起源复杂多样、高度可变。部分前列腺癌患者存在动静脉瘘,但只要术中选择合适的栓塞材料,PAE治疗前列腺癌源性下尿路梗阻或血尿仍然是安全、有效的。

Objective

To illustrate angiography findings in patients with prostate cancer during prostatic artery embolization (PAE).

Methods

The 2014.10-2019.12 angiograms of patients witha biopsy-proven diagnosis of prostate cancer during PAE were retrospectively analyzed. The number and origin of prostate artery (PA) and abnormal angiographic manifestations were observed. International Prostate Symptom Score (IPSS), quality of life (QoL) and complications at 3 and 12 months after PAE were collected to evaluate the efficacy of PAE in patients with abnormal angiographic manifestations.

Results

One hundred and twenty-one pelvic sides were detected (One pelvic side was not evaluated because of the internal iliac artery occlusion) and 147 PAs were identified. The origins of the PAs included the internal pudendal artery (n = 46, 31.3%), the vesical artery (n = 40, 27.3%), the obturator artery (n = 31, 21.1%), the gluteal-pudendal trunk (n = 23, 15.7%), the inferior gluteal artery (n = 3, 2.0%), the accessory pudendal artery (n = 3, 2.0%), and the superior gluteal artery (n = 1, 0.6%). Arteriovenous fistula was present in6 patients and significant improvements were observed in the 3rd and 12th month IPSS and QoL (P < 0.05 for both). No major complications were observed.

Conclusions

The origin of PAs was complex and highly variable. Although arteriovenous fistula was present in some patients with prostate cancer, PAE was still safe and effective as long as suitable embolic particles were used.

表1 61例患者髂动脉造影前列腺动脉起源分布(n = 61,%)
图1 65岁男性,前列腺癌,右侧髂内动脉造影显示两支前列腺动脉(分别起自右侧阴部内动脉的近端和远端)1A:右髂内动脉右前斜位造影显示前列腺动脉(白色箭头)起源于阴部内动脉;1B:右髂内动脉右前斜位造影显示另一条前列腺动脉(黑色箭头)起源于阴部内动脉远端,斜行向上。
图2 72岁男性,前列腺癌,DSA造影可见动静脉瘘征象2A:右髂内动脉右前斜位造影,显示阴部内动脉远端的动静脉瘘(白色箭头);2B:超选择前列腺动脉造影,显示动静脉瘘(黑色箭头)及邻近充盈的引流静脉;2C:左髂内动脉左前斜位造影,显示弥散性分布的动静脉瘘及充盈引流静脉;2D:超选择左侧阴部内动脉造影,显示阴部内动脉远端的微小动静脉瘘(白色箭头)。
表2 6例动静脉瘘患者术前情况及术后3、12个月IPSS、QoL评分
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