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中华介入放射学电子杂志 ›› 2020, Vol. 08 ›› Issue (03) : 216 -220. doi: 10.3877/cma.j.issn.2095-5782.2020.03.005

所属专题: 文献

专题研究·眼科介入

眼眶血管畸形介入硬化栓塞治疗的临床观察
蒋贻洲1, 姜华1, 申刚1, 刘珍银1, 张靖1,()   
  1. 1. 510120 广东广州,广州市妇女儿童医疗中心介入血管瘤科
  • 收稿日期:2020-06-08 出版日期:2020-08-25
  • 通信作者: 张靖

Clinical observation of interventional sclerotherapy and embolization for orbital vascular malformation

Yizhou Jiang1, Hua Jiang1, Gang Shen1, Zhenyin Liu1, Jing Zhang1,()   

  1. 1. Department of Interventional Radiology & Vascular Anomalies, Guangzhou Women and Children's Medical Center, Guangdong Guangzhou 510120, China
  • Received:2020-06-08 Published:2020-08-25
  • Corresponding author: Jing Zhang
  • About author:
    Corresponding author: Zhang Jing, Email:
引用本文:

蒋贻洲, 姜华, 申刚, 刘珍银, 张靖. 眼眶血管畸形介入硬化栓塞治疗的临床观察[J]. 中华介入放射学电子杂志, 2020, 08(03): 216-220.

Yizhou Jiang, Hua Jiang, Gang Shen, Zhenyin Liu, Jing Zhang. Clinical observation of interventional sclerotherapy and embolization for orbital vascular malformation[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2020, 08(03): 216-220.

目的

探讨介入硬化栓塞治疗眼眶血管畸形的方法,评价其临床疗效及安全性。

方法

回顾性分析2013年1月至2019年1月在我院收治的46例眼眶血管畸形患者(包括静脉畸形、动静脉畸形)的临床资料,其中静脉畸形33例,动静脉畸形13例。静脉畸形治疗均为经皮局部硬化治疗(药物为聚多卡醇/无水乙醇),动静脉畸形以经导管动脉硬化栓塞(栓塞剂为弹簧圈)及经皮局部硬化(药物为聚多卡醇/无水乙醇)联合治疗。随访时间15~57个月(中位随访时间35个月)。

结果

33例静脉畸形接受局部硬化治疗次数2~5次(平均3.5次),13例动静脉畸形接受介入治疗次数2~6次(平均3.9次)。33例静脉畸形至随访期结束时,13例治愈、11例症状明显缓解、9例部分缓解。13例动静脉畸形至随访期结束时,5例自觉血管搏动消失或明显缓解、8例眶周肿胀较前缓解。所有患者均有术后一过性眶周肿胀,未发生眶周皮肤破溃、视力衰退、眼球萎缩及异位栓塞等严重并发症。

结论

眼眶血管畸形行介入治疗安全,可以有效地缓解眶周症状。

Objective

To evaluate the clinical efficacy and safety of interventional sclerotherapy and embolization for orbital vascular malformations.

Methods

The clinical data of 46 cases of orbital vascular malformation(including venous malformation and arteriovenous malformation) in our hospital from January 2013 to January 2019 were retrospectively analyzed, including 33 cases of venous malformation and 13 cases of arteriovenous malformation. The patients with venous malformations were all treated by percutaneous local sclerotherapy (the drug was Polidocanol/absolute ethanol). The arteriovenous malformations were treated by transcatheter arteriosclerosis embolization with spring coil and percutaneous local sclerosis with Polidocanol/absolute ethanol.Forty-six patients obtained the clinical follow-up with a median of 30 (15-57) months.

Results

33 cases of venous malformations received local sclerotherapy 2-5 times (average 3.5 times), 13 cases of arteriovenous malformations received interventional treatment 2-6 times (average 3.9 times). By the end of follow-up in 33 patients with venous malformations, 13 cases were cured, 11 cases were obviously relieved and 9 cases were partially relieved. By the end of follow-up in 13 cases of AVM, 5 cases had no vascular pulsation or obvious relief, and 8 cases of periorbital swelling were relieved. All patients had transient periorbital swelling, and no serious complications such as orbital skin ulceration, visual deterioration, eyeball atrophy and ectopic embolism occurred.

Conclusions

Interventional treatment of orbital vascular malformation is safe and can effectively relieve the symptoms around the orbit.

图1 左眼眶内静脉畸形
图2 左眼眶动静脉畸形
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