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中华介入放射学电子杂志 ›› 2016, Vol. 04 ›› Issue (01) : 9 -12. doi: 10.3877/cma.j.issn.2095-5782.2016.01.003

所属专题: 文献

血管介入

胸主动脉腔内修复术治疗急性Stanford B型主动脉夹层前后的生化指标变化
逯党辉1, 翟水亭2, 李天晓3,(), 朱绍成1, 张志东2, 梁凯2, 王国权2   
  1. 1. 453003 新乡医学院
    2. 450003 河南省人民医院血管外科
    3. 450003 河南省人民医院介入科
  • 收稿日期:2015-12-01 出版日期:2016-02-01
  • 通信作者: 李天晓
  • 基金资助:
    国家临床重点专科建设项目(卫办医政函[2011]873号)

The biochemical index in the patients of acute type B aortic dissection before and after TEVAR

Danghui Lu1, Shuiting Zhai2, Tianxiao Li3,(), Shaocheng Zhu1, Zhidong Zhang2, Kai Liang2, Guoquan Wang2   

  1. 1. Xinxiang Medical University, Xinxiang 453003, China
    2. Department of Vascular Surgery, Henan Provincal People's Hospital, Zhengzhou 450003, China
    3. Department of Intervention Therapy, Henan Provincal People's Hospital, Zhengzhou 450003, China
  • Received:2015-12-01 Published:2016-02-01
  • Corresponding author: Tianxiao Li
  • About author:
    Corresponding author: Li Tianxiao,Email:
引用本文:

逯党辉, 翟水亭, 李天晓, 朱绍成, 张志东, 梁凯, 王国权. 胸主动脉腔内修复术治疗急性Stanford B型主动脉夹层前后的生化指标变化[J/OL]. 中华介入放射学电子杂志, 2016, 04(01): 9-12.

Danghui Lu, Shuiting Zhai, Tianxiao Li, Shaocheng Zhu, Zhidong Zhang, Kai Liang, Guoquan Wang. The biochemical index in the patients of acute type B aortic dissection before and after TEVAR[J/OL]. Chinese Journal of Interventional Radiology(Electronic Edition), 2016, 04(01): 9-12.

目的

研究急性Stanford B型主动脉夹层患者行胸主动脉腔内修复术(TEVAR)前后相关实验指标变化情况,评估腔内治疗的近期效果。

方法

筛选2012年11月—2013年11月我科收治并行TEVAR的急性Stanford B型主动脉夹层60例,分别检测其术前及术后生化指标白细胞总数、中性粒细胞、淋巴细胞、单核细胞、谷丙转氨酶、谷草转氨酶、尿素氮、肌酐、胱抑素C的变化情况。

结果

60例患者TEVRA前后白细胞总数及中性粒细胞总数平均值均高于正常范围,术前及术后对比无明显差异(P>0.05)。TEVAR前谷丙转氨酶及谷草转氨酶平均值均高于正常范围,其中谷丙转氨酶升高占30%,谷草转氨酶升高占21.7%,TEVAR后谷丙转氨酶及谷草转氨酶明显低于术前(P <0.05),其平均值下降至正常范围。TEVAR前尿素氮、肌酐及胱抑素C平均值均高于正常,其中尿素氮升高占31.7%,肌酐升高占30%,胱抑素C升高占35%,TEVAR后尿素氮及肌酐明显下降(P <0.05),胱抑素C比术前降低不明显(P>0.05)。

结论

TEVAR可以明显改善急性Stanford B型主动脉夹层患者的肝肾功能,对急性Stanford B型主动脉夹层近期效果良好,但远期效果还需大样本长期随访。

Objective

To study the change of laboratory indexes in the patients of acute type B aortic dissection before and after TEVAR, and to assess the validity of TEVAR.

Methods

Between November 2012 and November 2013, a total of 60 patients suffered from acute aortic dissection and underwent TEVAR. The laboratory indexes before and after TEVAR, were compared using SPSS 21.0 statistical software.

Results

The average amount of WBC and neutrophils is higher than the normal range before TEVAR ,so it is after TEVAR(P>0.05).Before the TEVAR, the average amount of ALT and AST are both higher than the normal range,30% of ALT is higher than the normal range,and 21.7% of AST is higher than the normal range.Both the ALT and AST after TEVAR is lower than the preoperative(P<0.05). The average amount of BUN, Cr and cystatin C are higher than the normal range. Before the TEVAR, 31.7% of BUN is higher than normal, 30% of Cr is higher than noamal ,and the number in cystatin C is 35% .The BUN and Cr are lower in the patients after TEVAR (P<0.05) , but the decline was not obvious in cystatin C.

Conclusions

For the patients with acute type B aortic dissection, the liver function and renal function both improved obviously after TEVAR.The immediate result of TEVAR in the patients of acute type B aortic dissection is good. The long term results is required for a larger sample.

表1 60例急性Stanford B型主动脉夹层患者的基本资料
表2 TEVAR前、后的白细胞指标变化情况(n=60,×109/L, ±s
表3 TEVAR前、后的肝肾功能变化情况(n=60, ±s
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