切换至 "中华医学电子期刊资源库"

中华介入放射学电子杂志 ›› 2015, Vol. 03 ›› Issue (01) : 4 -8. doi: 10.3877/cma.j.issn.2095-5782.2015.01.002

所属专题: 文献

血管介入

急症动脉性消化道大出血的介入治疗价值分析
王浩1, 陈光1,(), 高海军1, 伊正甲1, 温连芳1, 王鹏辉1, 杨颐馨1, 张丽1   
  1. 1. 300192 天津市第一中心医院放射科,天津影像医学研究所
  • 收稿日期:2013-12-07 出版日期:2015-02-01
  • 通信作者: 陈光

Analysis of the Interventional Therapy Value in the Acute Gastrointestinal Arterial Hemorrhage

Hao Wang1, Guang Chen1,(), Haijun Gao1, Zhengjia Yi1, Lianfang Wen1, Penghui Wang1, Yixin Yang1, Li Zhang1   

  1. 1. Department of Radiology, First Center Hospital; Medical Imaging Institute of Tianjin, Tianjin 300192, China
  • Received:2013-12-07 Published:2015-02-01
  • Corresponding author: Guang Chen
  • About author:
    Corresponding author: Chen Guang, Email:
引用本文:

王浩, 陈光, 高海军, 伊正甲, 温连芳, 王鹏辉, 杨颐馨, 张丽. 急症动脉性消化道大出血的介入治疗价值分析[J]. 中华介入放射学电子杂志, 2015, 03(01): 4-8.

Hao Wang, Guang Chen, Haijun Gao, Zhengjia Yi, Lianfang Wen, Penghui Wang, Yixin Yang, Li Zhang. Analysis of the Interventional Therapy Value in the Acute Gastrointestinal Arterial Hemorrhage[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2015, 03(01): 4-8.

目的

探讨急症动脉性消化道大出血的介入治疗价值。

方法

回顾性分析因消化道大出血急症行动脉造影的75例患者资料,将休克指数<1的病例规定为A组,休克指数≥1的病例规定为B组,对比分析A、B两组的阳性检出率。将使用螺圈栓塞的病例规定为C组,明胶海绵联合螺圈栓塞的病例规定为D组,对比分析C、D两组的复发率。分析影响阳性检出率、出血复发以及严重并发症发生的因素。

结果

该75例患者的首次阳性检出率为56%(42/75),A、B两组病例的阳性检出率有统计学意义(P<0.05),其余33例首次检查结果为阴性的患者有3例再次接受造影检查发现出血点,全部45例造影阳性的患者均接受介入栓塞治疗,技术成功率为100%。C、D两组的出血复发率无统计学意义(P>0.05),D组有2例患者发生肠道缺血坏死。

结论

介入栓塞是目前治疗胃肠道动脉性出血的重要方法,不但能够明确诊断,而且能够通过治疗挽救患者生命,一旦诊断为动脉性消化道大出血,应该尽早行介入治疗。

Objective

To investigate interventional therapy value in the acute gastrointestinal arterial hemorrhage.

Methods

Date of 75 patients with arteriography for the acute gastrointestinal hemorrhage was retrospectively analyzed, and cases in which the shock index<1 were divided as group A, the shock index ≥1 as group B. Comparative analysis of the positive detection rate were made in the two groups. Cases using coil to embolize prescribed as group C, and cases with gelatin sponge coil embolism prescribed as group D. Comparative analysis of recurrence rate were made in these two groups .Factors affecting the positive detection rate, recurrence of bleeding and severe complications were analyzed in the end.

Results

Positive detection rate of 75 cases was 56% (42/75), and it has statistic significance of positive detection rate in group A and B (P <0.05). All 42 patients with contrast positive took the interventional embolic treatment, for technical success rate was 100%. Recurrence rate of bleeding in group C and D has no statistic significance (P>0.05). Two cases of intestinal ischemia necrosis showed in these two groups. Three patients with negative results of DSA examination were found re-bleeding after radiography, whereas interventional therapy was done at the same time.

Conclusions

Interventional embolization is one of the vital methods in treatment of gastrointestinal arterial hemorrhage, not only can clarify diagnosis, but also save patients life promptly. Interventional therapy therefore should be done as soon as possible when patients diagnosed as gastrointestinal hemorrhage.

表1 出血原因
表2 出血部位
表3 A、B两组的阳性检出率
表4 C、D两组的出血复发率
图1 病例1,临床提示下消化道出血,首先以Cobra导管置于肠系膜上动脉造影,未见直接征象,但可见回结肠动脉痉挛表现(A),进一步以微导管超选择至回结肠动脉造影,可见回结肠动脉一分支对比剂外溢征象(B),在非减影模式下出血征象更加明显(C),以螺圈栓塞后再次造影,未见对比剂外溢(D)
图2 病例2,因便鲜血急症行DSA检查,肠系膜上动脉以及肠系膜下动脉造影均未见出血征象(A、B),插管至右侧髂内动脉发现对比剂外溢、聚集(C,箭),进一步以微导管超选择插管造影,以非减影模式,可见两处明显的对比剂外溢、聚集(D,箭),由于出血动脉较细,无法接近,且患者不考虑手术治疗,考虑到直肠侧枝血管丰富,以大颗粒明胶海绵栓塞该出血动脉,再次行髂内动脉造影,未见出血征象(E)
图3 病例3,一例下消化道大出血患者,患者行DSA检查时已经休克,首次以Cobra导管及微导管造影均未见出血征象(A、B),患者经过内科支持治疗后再次发生消化道大出血,再次行DSA检查,可见对比剂外逸、集聚(C、D),以螺圈栓塞后再次造影,未见对比剂外溢(E)
1
Whitaker SC, Gregson RH.The role of angiography in the investigation of acute or chronic gastrointestinal haemorrhage[J]. Clin Radiol, 1993,47(6):382-388.
2
Wagner HE, Stain SC, Gilq M, et a1. Systematic assessment of massive bleeding of the lower part of the gastrointestinaI tract[J]. Surg Gynecol Obstel, 1992, 175(5):445-449.
3
Lee CW, Liu KL, Wang H, et a1.Transcatheter arterial embolization of acute upper gastrointestinal tract bleeding with N-butyl-2-cyanoacrylate[J]. J Vasc Interv Radiol, 2007, 18(2):209-216.
4
Eriksson LG, Ljungdahl M, Sundbom M, et al. Transcatheter arterial embolization versus surgery in the treatment of upper gastrointestinal bleeding after therapeutic endoscopy failure[J]. J Vasc Interv Radiol, 2008,19(10):1413-1418.
5
Sclafani SJ, Cooper R, Shaftan GW, et al. Arterial trauma:diagnostic and therapeutic angiography[J]. Radiology, 1986,161(1):165-172.
6
Larssen L, Moger T, Bjornbeth BA, et al. Transcatheter arterial embolization in the management of bleeding duodenal ulcers: A 5.5-year retrospective study of treatment and outcome[J]. Scand J Gastroenterol,2008,43(2):217-222.
7
Marini M, Gómez-Gutierrez M, Cao I, et a1.Endovascular treatment of splenomesenteric-portal vein thromboses during orthotopic livertransplantation[J]. J Vasc Interv Radiol, 2005,16(8):1135-1142.
8
Keeling WB, Armstrong PA, Stone PA, et al. Risk factors for recurrent hemorrhage after successful mesenteric arterial embolization[J].Am Surg,2006,72(9):802-807.
9
Okazaki M, Furui S, Higashihara H, et a1.Emergent embolotherapy of small intestine hemorrhage[J]. Gastrointest Radiol,1992,15(3):223-228.
[1] 张霞, 钟炎平, 杨军杰, 毛静, 雷旭, 高岚, 雷飞飞, 谭华炳. 恙虫病致急性上消化道大出血、多器官功能衰竭经动脉栓塞止血抢救成功一例及文献复习[J]. 中华实验和临床感染病杂志(电子版), 2022, 16(02): 132-136.
[2] 孙龙, 郝迎学, 王明启. 介入技术结合腔内修复手术治疗复杂腹主动脉瘤26例临床随访分析[J]. 中华普外科手术学杂志(电子版), 2021, 15(04): 464-467.
[3] 束翌俊, 杨自逸, 刘颖斌, 董平. 胃癌合并急性消化道大出血的处理和手术策略探讨[J]. 中华普外科手术学杂志(电子版), 2021, 15(02): 224-227.
[4] 陈明. 66例肝门胆管癌合并阻塞性黄疸病例介入治疗的回顾性分析[J]. 中华普外科手术学杂志(电子版), 2019, 13(05): 501-503.
[5] 冯健, 赵向前, 张航宇, 梁斌, 卢实春. 胰十二指肠切除术后门静脉系统严重出血诊断与治疗[J]. 中华肝脏外科手术学电子杂志, 2018, 07(06): 482-485.
[6] 唐晖, 丁凡, 姜在波, 赵辉, 李华, 易述红, 杨扬, 陈规划, 许赤. 切割球囊治疗肝移植术后胆管吻合口狭窄[J]. 中华肝脏外科手术学电子杂志, 2017, 06(05): 389-392.
[7] 张永杰, 邱应和, 沈宁佳. 胆胰外科术后迟发型性出血的介入治疗[J]. 中华肝脏外科手术学电子杂志, 2017, 06(03): 164-167.
[8] 瞿虎, 徐丽南, 王晶, 何科, 苏中振, 江春强. 肝细胞癌经导管动脉化疗栓塞术后紫尿袋症患者的诊治体会[J]. 中华肝脏外科手术学电子杂志, 2015, 04(06): 357-359.
[9] 中国医师协会介入医师分会. 中国肝细胞癌经动脉化疗栓塞治疗临床实践指南[J]. 中华介入放射学电子杂志, 2019, 07(03): 178-184.
[10] 唐郁宽, 张艳, 黄晨, 庄炜钊, 冯惠岗, 钟伟锋, 陈汉威, 黄益. 双向内膜下血管成形术治疗下肢动脉闭塞性疾病的临床应用[J]. 中华介入放射学电子杂志, 2016, 04(02): 77-81.
[11] 秦月兰, 刘艳辉, 莫伟, 阳秀春. SBAR沟通模式提升介入血管外科护士评判性思维倾向的研究[J]. 中华介入放射学电子杂志, 2015, 03(03): 161-163.
[12] 张东坡, 翟仁友, 李建军, 戴定可, 于平. 恶性梗阻性黄疸经皮肝穿刺胆汁引流前瞻性对照研究[J]. 中华介入放射学电子杂志, 2015, 03(03): 148-153.
[13] 穆永旭, 李启民, 刘海艳, 张磊, 何俊峰, 闫瑞强. 介入手术方式对子宫腺肌症患者的临床疗效分析[J]. 中华介入放射学电子杂志, 2015, 03(03): 132-134.
[14] 陈光, 高海军, 王浩, 温连芳, 王鹏辉, 杨颐馨. 肝移植术后肝动脉假性动脉瘤的介入治疗[J]. 中华介入放射学电子杂志, 2014, 02(04): 12-14.
[15] 李名安, 姜在波, 单鸿, 周斌, 张有用, 王皓帆, 黄明声, 钱结胜, 关守海. 经皮经肝肝内门体分流术的手术方法与临床应用[J]. 中华介入放射学电子杂志, 2014, 02(03): 1-4.
阅读次数
全文


摘要