Pulmonary embolism (PE) is a respiratory disease in which emboli fall off in the systemic circulation, leading to obstruction of pulmonary arteries and branches, causing pulmonary circulation dysfunction. The most common is pulmonary thromboembolism, commonly known as pulmonary embolism, which refers to pulmonary thromboembolism. Pulmonary embolism is the third most common cardiovascular disease in China with a high incidence, but its clinical symptoms are often non-specific, and the diagnosis requires unconventional examination methods. Therefore, it often leads to high mortality due to misdiagnosis, missed diagnosis or untimely diagnosis. If not treated in time, the total mortality rate of pulmonary embolism is 18%-30%, while the mortality rate after anticoagulant therapy is 2%-11%. Therefore, early diagnosis and treatment are very important for patients with pulmonary embolism. This article mainly summarizes the research progress of the diagnosis and treatment of pulmonary embolism based on evidence-based medical evidence at home and abroad.