To explore the association between D-type personality and the 90-day prognosis of acute ischemic stroke patients with anterior circulation.

A retrospective analysis was conducted on the data of patients with anterior circulation acute ischemic stroke who received treatment at the Fifth Affiliated Hospital of Sun Yat sen University from September 2022 to July 2023.The D-type personality scale (DS-14) was used to evaluate the negative affectivity (NA) and social inhibition (SI) dimensions of participants, and the median of each dimension in the study sample (NA ≥ 11 and SI ≥ 9) was used to assess whether stroke patients have a D-type personality. A score of 3-6 on the 90 day modified Rankin scale (mRS) is defined as poor functional prognosis. Using univariate and multivariate logistic regression analysis to clarify the correlation between D-type personality and poor prognosis at 90 days.

A total of 36 patients were enrolled in this study, of whom 16(44%) patients had a D-type personality tendency. There is a statistically significant difference (P = 0.019) in poor prognosis between patients with type D personality and those without type D personality at 90 days. Multivariate analysis showed that D-type personality (OR = 21.837, 95%CI: 1.287~370.557; P = 0.033), NA (OR = 1.208, 95%CI: 1.006~1.451; P = 0.043), SI (OR = 1.187, 95%CI: 1.012~1.392; P=0.035) is an independent risk factor for 90 day poor functional prognosis in patients with anterior circulation acute ischemic stroke.

D-type personality is independently associated with poor 90-day prognosis in patients with acute ischemic stroke in the anterior circulation.