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Chinese Journal of Interventional Radiology(Electronic Edition) ›› 2022, Vol. 10 ›› Issue (01): 83-87. doi: 10.3877/cma.j.issn.2095-5782.2022.01.015

• Review • Previous Articles     Next Articles

Progress in surface modification of nitinol stent

Lin Duan1, Yanyan He2, Tianxiao Li2, Song Chen2, Yingkun He2,(), Haigang Wu3,()   

  1. 1. Neurosurgery Department of Stroke Center, Henan University People's Hospital; Henan International Joint Laboratory of Cerebrovascular Disease
    2. Cerebrovascular Department of Interventional Center, Henan Provincial People's Hospital, Henan Zhengzhou 450003
    3. School of Sciences, Henan University, Henan Kaifeng 475004, China
  • Received:2021-04-07 Online:2022-02-25 Published:2022-03-23
  • Contact: Yingkun He, Haigang Wu
  • About author:
    Co-first authors: Duan Lin, He Yanyan

Abstract:

Recently, the biological metal materials have been widely utilized in medicinal implantation, and the main component of these materials are cobalt chromium, iron, magnesium, zinc, nickel and titanium, respectively. Owing to the excellent of mechanical properties and biocompatibility of nitinal, NiTi alloys have been widely applied in vascular interventional treatment. However, the critical unsolved problems of NiTi alloy network contains the immune-response, anti-erosion, delayed endothelialization and restenosis, which have limited the further application in vascular interventional treatments. By precisely regulating the components of coating layers of NiTi alloys, the biocompatibility and anti-erosion can be significantly improved, which is the critical direction for medical alloy surface modification. In this paper, the current research status of NiTi alloys as scaffold material is described from the biological characteristics and surface modification of NiTi alloys, and the problems faced by it in vascular implants are systematically analyzed.

Key words: Nitinol, Coating, Biomedical materials

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