Clinical observation of interventional sclerotherapy and embolization for orbital vascular malformation

doi:10.3877/cma.j.issn.2095-5782.2020.03.005

Abstract

Abstract:

Objective

To evaluate the clinical efficacy and safety of interventional sclerotherapy and embolization for orbital vascular malformations.

Methods

The clinical data of 46 cases of orbital vascular malformation(including venous malformation and arteriovenous malformation) in our hospital from January 2013 to January 2019 were retrospectively analyzed, including 33 cases of venous malformation and 13 cases of arteriovenous malformation. The patients with venous malformations were all treated by percutaneous local sclerotherapy (the drug was Polidocanol/absolute ethanol). The arteriovenous malformations were treated by transcatheter arteriosclerosis embolization with spring coil and percutaneous local sclerosis with Polidocanol/absolute ethanol.Forty-six patients obtained the clinical follow-up with a median of 30 (15-57) months.

Results

33 cases of venous malformations received local sclerotherapy 2-5 times (average 3.5 times), 13 cases of arteriovenous malformations received interventional treatment 2-6 times (average 3.9 times). By the end of follow-up in 33 patients with venous malformations, 13 cases were cured, 11 cases were obviously relieved and 9 cases were partially relieved. By the end of follow-up in 13 cases of AVM, 5 cases had no vascular pulsation or obvious relief, and 8 cases of periorbital swelling were relieved. All patients had transient periorbital swelling, and no serious complications such as orbital skin ulceration, visual deterioration, eyeball atrophy and ectopic embolism occurred.

Conclusions

Interventional treatment of orbital vascular malformation is safe and can effectively relieve the symptoms around the orbit.

Key words: Orbital vascular malformation, Intervention, Sclerotherapy and embolization

Yizhou Jiang, Hua Jiang, Gang Shen, Zhenyin Liu, Jing Zhang. Clinical observation of interventional sclerotherapy and embolization for orbital vascular malformation[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2020, 08(03): 216-220.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhjrfsxdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-5782.2020.03.005

https://zhjrfsxdzzz.cma-cmc.com.cn/EN/Y2020/V08/I03/216

Figures/Tables 2

References 20

[1]	Young SM, Kim YD, Lee JH, et al. Radiological analysis of orbital cavernous hemangiomas: A review and comparison between computed tomography and magnetic resonance imaging[J]. J Craniofac Surg, 2018, 29(3): 712-716.
[2]	Rootman J, Kao SC, Graeb DA. Multidisciplinary approaches to complicated vascular lesions of the orbit[J]. Ophthalmology, 1992, 99(9): 1440-1446.
[3]	Hayes BH, Shore JW, Westfall CT, et al. Management of orbital and periorbital arteriovenous malformations[J]. Ophthalmic Surg, 1995, 26(2): 145-152.
[4]	国际血管联盟中国分部血管畸形专家委员会．静脉畸形中国专家共识[J]．介入放射学杂志，2019, 28(4): 307-311.
[5]	Puig S, Aref H, Chigot V, et al. Classification of venous malformations in children and implications for sclerotherapy[J]. Pediatr Radiol, 2003, 33(2): 99-103.
[6]	Legiehn GM, Heran MK. Classification, diagnosis, and interventional radiologic management of vascular malformations[J]. Orthop Clin North Am, 2006, 37(3): 435-474, vii-viii.
[7]	Yakes W, Baumgartner I. Interventional treatment of arteriovenous malformations[J]. Gefasschirurgie, 2014, 19: 325-330.
[8]	蒋贻洲，申刚，刘浪，等．儿童眼眶内静脉畸形介入硬化疗法的疗效和安全性[J]．中华放射学杂志，2015, 49: 469-472.
[9]	Tessari L, Cavezzi A, Frullini A. Preliminary experience with a new sclerosing foam in the treatment of varicose veins[J]. Dermatol Surg, 2001, 27(1): 58-60.
[10]	苏彤，刘冰，赵吉宏，等．局部冷冻联合平阳霉素注射治疗颌面部静脉畸形[J]．中华整形外科杂志，2006, 22(6): 453-454.
[11]	Mulliken JB. A biologic approach to cutaneous vascular anomalies[J]. Pediatr Dermatol, 1992, 9(4): 356-357.
[12]	Wang D, Su L, Han Y, et al. Direct intralesional ethanol sclerotherapy of extensive venous malformations with oropharyngeal involvement after a temporary tracheotomy in the head and neck: Initial results[J]. Head Neck, 2017, 39(2): 288-296.
[13]	Soulez G, Gilbert Md Frcpc P, Giroux Md Frcpc MF, et al. Interventional management of arteriovenous malformations[J]. Tech Vasc Interv Radiol, 2019, 22(4): 100633.
[14]	Yang XT, Su LX, Fan XD. Intraosseous arteriovenous malformations in the extremities managed with coils and absolute ethanol treatment[J]. Ann Vasc Surg, 2020, 65: 152-159.
[15]	Nassiri N, Cirillo-Penn NC, Crystal DT. Direct stick embolization of extremity arteriovenous malformations with ethylene vinyl alcohol copolymer[J]. J Vasc Surg, 2017, 65(4): 1223-1228.
[16]	Kitagawa A, Yamamoto T, Matsunaga N, et al. Polidocanol sclerotherapy combined with transarterial embolization using n-butyl cyanoacrylate for extracranial arteriovenous malformations[J]. Cardiovasc Intervent Radiol, 2018, 41(6): 856-866.
[17]	Jin Y, Zou Y, Hua C, et al. Treatment of early-stage extracranial arteriovenous malformations with intralesional interstitial bleomycin injection: A pilot study[J]. Radiology, 2018, 287(1): 194-204.
[18]	Jin Y, Yang X, Hua C, et al. Ethanol embolotherapy for the management of refractory chronic skin ulcers caused by arteriovenous malformations[J]. J Vasc Interv Radiol, 2018, 29(1): 107-113.
[19]	Mack JM, Verkamp B, Richter GT, et al. Effect of sirolimus on coagulopathy of slow-flow vascular malformations[J]. Pediatr Blood Cancer, 2019, 66(10): e27896.
[20]	Gabeff R, Boccara O, Soupre V, et al. Efficacy and tolerance of sirolimus (rapamycin) for extracranial arteriovenous malformations in children and adults[J]. Acta Derm Venereol, 2019, 99(12): 1105-1109.

Please choose a citation manager

Content to export