Analysis of factors that impacts prognostic of interventional therapy for DVT

doi:10.3877/cma.j.issn.2095-5782.2016.01.008

Abstract

Abstract:

Objective

This paper is to analyze the outcome and risk factors of interventional therapy for lower extremity deep venous thrombosis.

Methods

From July 2012 to June 2015, 65 patients (27 men and 38 women) underwent interventional therapy for deep venous thrombosis of lower extremity. 16 patients underwent conservative therapy, 23 patients underwent catheter-directed thrombolysis, 26 patients underwent mechanical thrombolysis plus catheter-directed thrombolysis.

Results

Follow up duration are 1 to 30 months. During the follow up duration, 13 patients replase or fail treated, the cured rate was 80.0%. The average hospitalization time is 16.2 d.The result of single factor study and logistic regression analysis show that the treatment methods and the stages of thrombosis are the prognosis factors. Multivariate multiple linear regression analysis show that the stages and location of thrombosis, and the filter influence the duration of hospitalization.

Conclusions

The treatment methods and the stages of thrombosis influence the prognosis of DVT with thrombolysis therapy. The stages ,locations of thrombosis and the filter will influence the duration of hospitalization.

Key words: Lower extremity deep venous thrombosis, Interventional thrombolysis, Duration of hospitalization, Prognosis, Interventional treatment

Chen Huang, Huigang Feng, Weizhao Zhuang, Huizhuang Guo, Yi Huang, Peiling Hu, Jianyun Mai, Hanwei Chen, Yukuan Tang. Analysis of factors that impacts prognostic of interventional therapy for DVT[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2016, 04(01): 27-31.

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References 12

1	中华医学会放射分会介入学组. 下肢深静脉血栓形成介入治疗规范的专家共识[J]. 介入放射学杂志，2011，20(7):505-510. doi:10.3969/j.issn.1008-794X.2011.07.001.
2	Kluge A，Mueller C，Strunk J，et al. Experience in 207 combined MRI examinations for acute pulmonary embolism and deep vein thrombosis[J].AJR，2006，186(62):1686-1696.
3	中华医学会放射分会介入学组. 下腔静脉滤器置入术和取出术规范的专家共识[J]. 介入放射学杂志，2011，20(5):340-344. doi:10.3760/cma.j.issn.1005-1201.2011.03.015.
4	汤永胜，刘咸罗，陈克辉，等. 急性下肢深静脉血栓形成52例诊治体会[J]. 安徽医学，2012，33 (1):33-35. doi:10.3969/j.issn.1000-0399.2012.01.013.
5	李明，吴小鹏、王志青. 下肢深静脉血栓形成手术时机的探讨[J]. 中国现代普通外科进展，2006，9(4):243-244.
6	唐郁宽，陈汉威，陈勇. 顺行插管综合接入治疗下肢深静脉血栓[J]. 中华放射学杂志，2003，37(1):33-36.
7	张柏根. 下肢深静脉血栓形成治疗和预后的几个问题[J]. 中华普通外科杂志，2006，21(2):81-83.
8	郭曙光，陈翠菊，周兴立，等. 下腔静脉滤器在下肢深静脉血栓治疗中的应用[J]. 中国普通外科杂志，2003,12(6):446-448.
9	赵伯翔，顾建平，陈国平，等. D-二聚体监测在治疗急性髂股静脉血栓形成中的临床价值[J].介入放射学杂志, 2013,22(6):464-469. doi:10.3969/j.issn.1008-794X.2013.06.006.
10	Malato A，Saccullo G，Iorio A，et al. Residual vein thrombosis and D-dimer for optimizing duration of anticoagulation in idiopathic deep vein thrombosis[J]. Curr Pharm Des，2010，16(31):3483-3486.
11	Kahn SR. The post-thrombotic syndrome：the forgotten morbidity of deep venous thrombosis[J]. J Thromb Thrombolysis，2006，21(1):41-48.
12	张柏根. 下肢深静脉血栓形成治疗和预后的几个问题[J]. 中华普通外科杂志，2006，21(2):81-83.

变量	β	SE	P	OR(95%CI)
病程	1.724	0.148	0.003	3.307(1.181～9.259)
治疗方法	-0.481	0.138	0.002	0.386(0.136～0.873)
血栓解剖部位	0.214	0.203	0.291	1.239(0.712～1.102)
滤器	-0.001	0.010	0.905	0.999(0.979～1.019)

变量	β	SE	P	OR(95%CI)
病程	1.724	0.148	0.003	3.307(1.181～9.259)
治疗方法	-0.481	0.138	0.002	0.386(0.136～0.873)
血栓解剖部位	0.214	0.203	0.291	1.239(0.712～1.102)
滤器	-0.001	0.010	0.905	0.999(0.979～1.019)

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