Clinical efficacy analysis of mechanical thrombectomy in patients with wake-up stroke based on multi-modal CT imaging

doi:10.3877/cma.j.issn.2095-5782.2021.01.012

Abstract

Abstract:

Objective

To investigate the clinical characteristics of wake-up stroke and the efficacy of mechanical thrombectomy in patients with wake-up stroke after multi-modal CT evaluation.

Methods

A total of 189 inpatients with acute ischemic stroke caused by large artery occlusion and multi-modal CT evaluation treated with mechanical thrombectomy were divided into WUS group (58 cases) and non-WUS group (131 cases). Preoperative baseline data, national Institutes of Health Stroke Scale (NIHSS) score 24 hours after thrombectomy, NIHSS score 7 days after surgery, number of patients with improved NIHSS score during hospitalization , and number of patients with modified Rankin scale (mRS) score ≥3 points at 90 days were compared between the two groups.

Results

There were no statistically significant differences between the two groups in preoperative baseline data except for atrial fibrillation. The NIHSS score 24 hours after thrombectomy, NIHSS score 7 days after thrombectomy and number of patients with mRS score ≥3 points at 90 days were lower in the group of WUS, but there were no statistically significant differences between the two groups (P > 0.05).

Conclusions

The onset of wake-up stroke is closely related to atrial fibrillation. The clinical efficacy of thrombectomy was similar both in patients with wake-up stroke and non-wake-up stroke based on multi-modal CT imaging.

Key words: Wake-up stroke, Mechanical thrombectomy, Multi-modal CT, Atrial fibrillation

Yun Zhou, Yonggang Li, Bo Li, Qi Fang, Hui Wang. Clinical efficacy analysis of mechanical thrombectomy in patients with wake-up stroke based on multi-modal CT imaging[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2021, 09(01): 70-74.

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Figures/Tables 2

References 20

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临床资料		WUS组（n = 58）	NWUS组（n = 131）	P值
男性		35（60.34%）	070（53.44%）	> 0.05
年龄		64.44±10.21	64.9±10.34	> 0.05
高血压		36（62.07%）	075（57.25%）	> 0.05
糖尿病		05（8.62%）	013（9.92%）	> 0.05
房颤^a		39（67.24%）	043（32.82%）	< 0.05
吸烟		10（17.24%）	020（15.26%）	> 0.05
饮酒史		03（5.17%）	010（7.63%）	> 0.05
LDL-C水平（mmol/L）		2.72±0.85	2.70±0.64	> 0.05
基线NIHSS评分		13.43±6.08	13.92±6.17	> 0.05
卒中血管分布
	前循环	45（77.59%）	100（76.34%）	> 0.05
	后循环	13（22.41%）	031（23.66%）

临床资料		WUS组（n = 58）	NWUS组（n = 131）	P值
男性		35（60.34%）	070（53.44%）	> 0.05
年龄		64.44±10.21	64.9±10.34	> 0.05
高血压		36（62.07%）	075（57.25%）	> 0.05
糖尿病		05（8.62%）	013（9.92%）	> 0.05
房颤^a		39（67.24%）	043（32.82%）	< 0.05
吸烟		10（17.24%）	020（15.26%）	> 0.05
饮酒史		03（5.17%）	010（7.63%）	> 0.05
LDL-C水平（mmol/L）		2.72±0.85	2.70±0.64	> 0.05
基线NIHSS评分		13.43±6.08	13.92±6.17	> 0.05
卒中血管分布
	前循环	45（77.59%）	100（76.34%）	> 0.05
	后循环	13（22.41%）	031（23.66%）

临床资料	WUS组（n = 58）	NWUS组（n = 131）	P值
术后24 h NHISS评分	11.19±6.21	12.12±6.13	> 0.05
术后7 d NHISS评分	7.79±6.04	8.36±6.64	> 0.05
住院期间NIHSS
评分改善人数	30（51.72%）	57（43.51%）	> 0.05
90 d mRS≥3分人数	10（17.24%）	15（11.45%）	> 0.05

临床资料	WUS组（n = 58）	NWUS组（n = 131）	P值
术后24 h NHISS评分	11.19±6.21	12.12±6.13	> 0.05
术后7 d NHISS评分	7.79±6.04	8.36±6.64	> 0.05
住院期间NIHSS
评分改善人数	30（51.72%）	57（43.51%）	> 0.05
90 d mRS≥3分人数	10（17.24%）	15（11.45%）	> 0.05

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