3D printed template and CT-guided brachytherapy for prostate cancer: A case report and review of literature

doi:10.3877/cma.j.issn.2095-5782.2019.03.005

Abstract

Abstract:

Objective:

To investigate the feasibility and safety of 3D printed template and CT-guided trans-pararectal ¹²⁵I seed brachytherapy for prostate cancer.

Methods:

An old patient with prostate cancer in our hospital was enrolled. He was treated by radiotherapy but did not finish the whole course because of the complication of the rectum. 3D printed template guided brachytherapy was used for a dose boost. An enhanced CT was performed after the patient was fixed in a prone position by a vacuum pad. The 3D printed template was made after the dose parameter in pre-plan was satisfied. During the procedure, the template was fixed on the surface of the patient's hip when the patient was fixed by the vacuum pad in the same prone position as before. The needles were inserted into the prostate through the skin and both sides of the rectum after local anesthesia. ¹²⁵I seeds were implanted into prostate according to pre-plan when CT showed all the needles were in the right place.

Results:

All the needles can be inserted into the right location according to pre-plan under the guidance of 3D printed template. The seeds location and dose parameter post-implant were the same with that in pre-plan. Complications such as hemorrhage, injury of the urethra and rectum were not found. The PSA reduced from preoperative 10.16 ng/ml to 6.93 ng/ml 2 month after the procedure and the tumor was stable disease evaluated by CT scan.

Conclusions:

Trans-pararectal ¹²⁵I seeds implantation guided by 3D printed template and CT under local anesthesia was a safe and time-saving way for prostate cancer.

Key words: Brachytherpay, 3D print, Prostate cancer, ¹²⁵I seed, Dose

Hongtao Zhang, Xiaohua Su, Yansong Liang, Zhen Gao, Huimin Yu, Jinxin Zhao, Aixia Sui, Juan Wang. 3D printed template and CT-guided brachytherapy for prostate cancer: A case report and review of literature[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2019, 07(03): 197-201.

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