To investigate and analyze the distribution of main pathogenic bacteria in bile of patients with postoperative biliary infection after liver puncture percutaneous biliary drainage (PTCD) treatment and their sensitivity to different antibiotics.

The patients (219 cases) with biliary tract infection after PTCD treatment were collected in June 2014-June 2016, the bile samples were gathered, and bacteria+fungus culture and drug sensitive test were performed and analyzed.

(1) The 219 bile samples were collected, a total of 253 strains were obtained, containing 20 kinds and including 194 strains of G^- bacteria (76.7%) , 53 strains of G⁺ bacteria (20.9%) and 6 strains of fungus (2.4%) ; The top three G^- bacteria were Escherichia coli (93 strains, 36.7%) , Klebsiella pneumoniae (39 strains, 15.4%) and Pseudomonas aeruginosa (18 strains, 7.1%) . The top two G⁺ bacteria were Enterococcus faecium (17 strains, 6.7%) and Enterococcus faecalis (14 strains, 5.5%) ; The fungi were mainly Candida albicans (3 strains, 1.2%) . (2) Antibacterial drugs with high sensitivity to G^- bacteria included carbapenems, aminoglycosides and cephalosporins; Antibacterial drugs with high sensitivity to G⁺ bacteria included quinolones, oxazolanone and glycoside antibiotics. Fungi were sensitive to triazole antifungal drugs.

G^- bacteria are the main pathogenic bacteria in the bile of patients with biliary tract infection after PTCD treatment, followed by G⁺ bacteria and fungi, and some cases are mixed infection.