To explore the safety, feasibility, economy and effectiveness of large-size coils embolization.

40 consecutive patients with intracranial aneurysms treated with large-size coils (the first coil was obviously larger than the diameter of the aneurysm) from January to December 2016 in our center were analyzed retrospectively. Endovascular coiling treatment detials were analyzed according to the cerebral angiography immediately after treatment.

A total of 40 aneurysms in 40 patients received endovascular treatment with sith large-size coils, 24 ruptured and 16 unruptured. The mean largest diameter of the aneurysms was (6.27±2.76) mm, the mean diameter of the aneurysms was (5.28±2.27) mm, of which 21 cases were embolized, 19 cases embolized with the assistence of stent. An average of (3.26±1.48) coils with a mean length of (34.95±27.22) cm per aneurysm was used, resulting in a mean packing density of (18.32±6.39) %. The angiography immediately after treatment showed that among the 40 intracranial aneurysms 39 belonged to Raymond grade Ⅰ, 1 belonged to Raymond grade Ⅱ. No procedural aneurysm rupture and thromboembolic events observed during the operation. Follow-up angiography 6 months after the treatment revealed that 39 aneurysms were Raymond grade Ⅰ, 1 aneurysms was Raymond grade Ⅱ. During the follow-up period, no death and re-bleeding events occurred.

For the treatment of intracranial aneurysms, large-size coils embolization is safe and effective although its long-term results need to be further studied.