The biochemical index in the patients of acute type B aortic dissection before and after TEVAR

doi:10.3877/cma.j.issn.2095-5782.2016.01.003

Abstract

Abstract:

Objective

To study the change of laboratory indexes in the patients of acute type B aortic dissection before and after TEVAR, and to assess the validity of TEVAR.

Methods

Between November 2012 and November 2013, a total of 60 patients suffered from acute aortic dissection and underwent TEVAR. The laboratory indexes before and after TEVAR, were compared using SPSS 21.0 statistical software.

Results

The average amount of WBC and neutrophils is higher than the normal range before TEVAR ,so it is after TEVAR(P>0.05).Before the TEVAR, the average amount of ALT and AST are both higher than the normal range,30% of ALT is higher than the normal range,and 21.7% of AST is higher than the normal range.Both the ALT and AST after TEVAR is lower than the preoperative(P<0.05). The average amount of BUN, Cr and cystatin C are higher than the normal range. Before the TEVAR, 31.7% of BUN is higher than normal, 30% of Cr is higher than noamal ,and the number in cystatin C is 35% .The BUN and Cr are lower in the patients after TEVAR (P<0.05) , but the decline was not obvious in cystatin C.

Conclusions

For the patients with acute type B aortic dissection, the liver function and renal function both improved obviously after TEVAR.The immediate result of TEVAR in the patients of acute type B aortic dissection is good. The long term results is required for a larger sample.

Key words: Aortic dissection, TEVAR, Liver function, Renal function

Danghui Lu, Shuiting Zhai, Tianxiao Li, Shaocheng Zhu, Zhidong Zhang, Kai Liang, Guoquan Wang. The biochemical index in the patients of acute type B aortic dissection before and after TEVAR[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2016, 04(01): 9-12.

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Figures/Tables 3

References 12

1	Erbel R, Alfonso F, Boileau C, et al. Diagnosis and management of aortic dissection[J]. Eur Heart，2001，22(18):1642-1681.
2	Steuer J, Eriksson MO, Nyman R, et al. Early and long-term outcome after thoracic endovascular aortic repair (TEVAR) for acute complicated type B aortic dissection[J]. Eur J Vasc Endovasc Surg, 2011, 41(3):318-323. doi: 10.1016/j.ejvs.2010.11.024.
3	Kuehl H, Eggebrecht H, Boes T, et al. Detection of inflammation in patients with acute aortic syndrome: comparison of FDG-PET/CT imaging and serological markers of inflammation[J]. Heart, 2008，94(11): 1472-1477.
4	Mitsuoka M, Inoue N, Mori S,et al.Renal dysfunction on admission as a predictor for in-hospital mortality of patients with stanford type B acute aortic dissection[J].Ann Vasc Dis，2013，6(3):624-630. doi: 10.3400/avd.oa.13-00034.
5	Luo F, Zhou XL, Li JJ, et al. Inflammatory response is associated with aortic dissection[J]. Ageing Res Rev，2009，8(1): 31-35. doi: 10.1016/j.arr.2008.08.001.
6	del Porto F, Proietta M, Tritapepe L, et al.Inﬂammation and immune response in acute aortic dissection[J].Ann Med,2010，42(8): 622-629. doi: 10.3109/07853890.2010.518156.
7	王深明，李晓曦.血管外科学[M].第一版.北京：人民卫生出版社，2011：415-416.
8	刘楠，孙立忠，常谦. 主动脉夹层手术后肝功能不全发生的相关危险因素分析[J].中华外科杂志，2010, 48(15):1154-1157. doi:10.3760/cma.j.issn.0529-5815.2010.15.009.
9	Kipfer B，Savolainen H，Egger B，et al．Delayed visceral malperfusion in aortic dissection—successful surgical revaseularization using a saphenous vein graft[J]．Eur J Cardiothorac Surg，2005,28(6):903-905．
10	Beckman JA, Mehta RH, Isselbacher EM, et al．Branch vessel complications are increased in aortic dissection patients with renal insufficiency[J] .Vasc Med，2004, 9(4): 267-270.
11	Fattori R, Montgomery D, Lovato L，et al. Survival after endovascular therapy in patients with type B aortic dissection: a report from the International Registry of Acute Aortic Dissection (IRAD)[J]. JACC Cardiovasc Interv, 2013,6(8):876-882. doi: 10.1016/j.jcin.2013.05.003.
12	Verhoye JP, De Latour B, Heautot JF. Return of renal function after endovascular treatment of aortic dissection[J]. N Engl J Med, 2005,352(17):1824-1825.

指标	最小值	最大值	± s
年龄（岁）	34	85	56.0±12.4
体质指数（kg/m²）	19.8	32.7	24.6±2.7
发病至入院时间(h)	5	168	27.3±31.7
入院时收缩压（mmHg）	128	196	168.4±16.9
入院时舒张压（mmHg）	74	118	90.0±10.3
住院天数（d）	12.0	33.0	17.9±4.1

指标	最小值	最大值	± s
年龄（岁）	34	85	56.0±12.4
体质指数（kg/m²）	19.8	32.7	24.6±2.7
发病至入院时间(h)	5	168	27.3±31.7
入院时收缩压（mmHg）	128	196	168.4±16.9
入院时舒张压（mmHg）	74	118	90.0±10.3
住院天数（d）	12.0	33.0	17.9±4.1

时间	白细胞总数	中性粒细胞数	淋巴细胞数	单核细胞数
TEVAR前	11.0±4.8	8.9±4.7	2.0±1.3	0.6±0.2
TEVAR后	11.8±9.4	9.0±8.0	1.6±1.3	0.6±0.3
t值	0.58	0.05	0.84	0.09
P值	0.57	0.96	0.41	0.93

时间	白细胞总数	中性粒细胞数	淋巴细胞数	单核细胞数
TEVAR前	11.0±4.8	8.9±4.7	2.0±1.3	0.6±0.2
TEVAR后	11.8±9.4	9.0±8.0	1.6±1.3	0.6±0.3
t值	0.58	0.05	0.84	0.09
P值	0.57	0.96	0.41	0.93

时间	谷丙转氨酶（U/L）	谷草转氨酶（U/L）	尿素氮（mmol/L）	肌酐（μmol/L）	胱抑素C（mg/L）
TEVAR前	45.2±29.5	53.7±26.7	7.6±4.2	120.7±14.9	1.06±0.57
TEVAR后	35.7±24.2	32.3±21.9	6.5±3.6	98.6±12.5	0.97±0.49
t值	2.09	2.16	3.10	2.84	1.23
P值	0.042	0.035	0.003	0.010	0.300

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