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Chinese Journal of Interventional Radiology(Electronic Edition) ›› 2015, Vol. 03 ›› Issue (01): 27-33. doi: 10.3877/cma.j.issn.2095-5782.2015.01.007

Special Issue:

• Medical Imaging • Previous Articles     Next Articles

CT and MR findings of hepatic sinusoidal obstruction syndrome caused by Gynura segetum

Tianhe Ye1, Huimin Liang1,(), Jin Ye1, Chuansheng Zheng1, Bin Xiong1, Feng Pan1, Xiangwen Xia1, Feng Yuan1, Ran Tao1   

  1. 1. Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
  • Received:2013-12-05 Online:2015-02-01 Published:2015-02-01
  • Contact: Huimin Liang
  • About author:
    Corresponding author: Liang Huimin, Email:

Abstract:

Objective

to explore the imaging manifestations of sinusoidal obstruction syndrome (HSOS) caused by Gynura segetum.

Methods

A total of 20 cases of HSOS caused by consuming Gynura segetum were confirmed by clinical diagnosis and liver biospy. Including them there are 19 males and 1 female; 12cases confirmed by the liver biospy, 8 cases with clinical manifestations, medical history and lab examinations comprehensive diagnosis. All patients had trauma, stroke history, after taking 10 days to 6 months of clinical symtoms. The clinical data, CT and MR imagings had be analyzed in this article.

Results

A total of 14 cases underwent CT scan and 11 cases accepted MRI examination. Unenhanced CT features are heterogenous hypodensity of liver parenchyma, the portal venous and delayed phases of hepatic enhancement performed uneven and poorly perfusion. The MRI examination can show the liver parenchyma more clearly than the CT scan, the liver parenchyma along the three main hepatic veins appears higher and more even signal than the rest part of the liver. The three main hepatic veins seemed tiny, light or absence, the inferior vena cava became compressed but unobstructed. The periportal edema and portal hypertension also represented.

Conclusions

The HSOS caused by Gynura segetum have a certain degree of typical imaging findings. The CT and MRI examination have a important role in the review and evaluation of clinical efficacy. The MRI examination can better assess the liver parenchymal damage and intrahepatic venous situation, the imaging postprocessing technique of CT can clearly show the inferior vena cava and intrahepatic vessels. These two examination have important effect in diagnosis and differential diagnosis of HSOS, combing with Gynura segetum consuming history and pathological examination, can help to suggest the diagnosis of HSOS.

Key words: Gynura segetum, Hepatic sinusoidal obstruction, Tomography, X-ray computed, Magnetic resonance imaging

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