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中华介入放射学电子杂志 ›› 2026, Vol. 14 ›› Issue (02) : 184 -187. doi: 10.3877/cma.j.issn.2095-5782.2026.02.009

论著

明胶海绵-碘海醇浆在肝硬化中度血小板减少患者经皮肝穿刺中的应用
沈小娇, 更藏尖措(), 吴学荣, 颜小明, 韩慧英, 刘锦阳   
  1. 810000 青海西宁,青海省第四人民医院介入科
  • 收稿日期:2025-12-08 出版日期:2026-05-25
  • 通信作者: 更藏尖措
  • 基金资助:
    青海省卫生健康系统指导性计划(2022-wjzdx-67)

Application of Gelatin Sponge-Iohexol Slurry in Percutaneous Liver Biopsy for Cirrhotic Patients with Moderate Thrombocytopenia

Xiaojiao Shen, Xuerong Wu, Xiaoming Yan, Huiying Han, Jinyang Liu   

  1. Department of Interventional Radiology, The Fourth People's Hospital of Qinghai Province, Xining 810000, China
  • Received:2025-12-08 Published:2026-05-25
引用本文:

沈小娇, 更藏尖措, 吴学荣, 颜小明, 韩慧英, 刘锦阳. 明胶海绵-碘海醇浆在肝硬化中度血小板减少患者经皮肝穿刺中的应用[J/OL]. 中华介入放射学电子杂志, 2026, 14(02): 184-187.

Xiaojiao Shen, Xuerong Wu, Xiaoming Yan, Huiying Han, Jinyang Liu. Application of Gelatin Sponge-Iohexol Slurry in Percutaneous Liver Biopsy for Cirrhotic Patients with Moderate Thrombocytopenia[J/OL]. Chinese Journal of Interventional Radiology(Electronic Edition), 2026, 14(02): 184-187.

目的

探讨明胶海绵-碘海醇浆在中度血小板减少[血小板计数(20~50) ×109/L]的肝硬化患者经皮肝穿刺活检术后针道封堵中的可行性及安全性。

方法

回顾性分析2023年3月至2025年3月在青海省第四人民医院接受CT引导下经皮肝穿刺活检的60例中度血小板减少的肝硬化患者的临床资料。所有患者术后均采用明胶海绵-碘海醇浆封堵针道,评估技术成功率,针道封堵成功率及并发症发生率。

结果

60例患者均顺利完成穿刺活检,技术成功率为100%;术后针道封堵成功率为100%。术后发生1级出血8例(13.3%),无2级及以上出血病例;出现局部轻微疼痛4例(6.7%),无穿刺点感染、胆管损伤、气胸、发热及异位栓塞等情况发生。

结论

初步观察表明,应用明胶海绵-碘海醇浆对中度血小板减少的肝硬化患者中进行针道封堵是安全、可行的。

Objective

To evaluate the feasibility and safety of gelatin sponge-iohexol slurry for tract sealing after percutaneous liver biopsy in cirrhotic patients with moderate thrombocytopenia (PLT 20–50×109/L).

Methods

A retrospective analysis was conducted on 60 patients with moderate thrombocytopenia who underwent CT-guided percutaneous liver biopsy at our hospital from March 2023 to March 2025. All patients underwent needle tract plugging with gelatin sponge-iohexol slurry immediately following the biopsy. The technical success rate, tract sealing success rate, and complication rates were evaluated.

Results

The technical success rates for both the biopsy procedure and tract sealing were 100%. Grade 1 bleeding occurred in 8 patients (13.3%), with no instances of Grade 2 or higher bleeding. Mild local pain was reported in 4 patients (6.7%). No complications such as puncture site infection, biliary injury, pneumothorax, fever, or non-target embolization occurred.

Conclusion

The use of gelatin sponge-iohexol slurry for tract sealing has preliminarily demonstrated safety and feasibility in cirrhotic patients with moderate thrombocytopenia.

图1 44岁男性患者腹部CT扫描图 图1A:穿刺前腹部轴位平扫CT图提示肝左叶病变;图1B:经皮肝穿活检取材;图1C:术后复查CT图示针道内高密度,肝周未见渗出影。
图2 29岁女性患者腹部CT扫描图 图2A:穿刺前腹部轴位平扫CT图;图2B:经皮肝穿活检取材;图2C:术后复查CT图示针道内高密度封堵剂影,肝周可见极少量封堵液外渗(箭头);图2D.观察20 min后复查肝周无变化,腹腔有无高密度渗出影。
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