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中华介入放射学电子杂志 ›› 2026, Vol. 14 ›› Issue (01) : 97 -102. doi: 10.3877/cma.j.issn.2095-5782.2026.01.014

综述

炎症标志物与外周动脉疾病相关性的研究进展
侯建宇, 纪东华()   
  1. 116011 辽宁大连,大连医科大学附属第一医院介入治疗科
  • 收稿日期:2025-05-20 出版日期:2026-02-25
  • 通信作者: 纪东华

Research Progress on the Correlation Between Inflammatory Markers and Peripheral Artery Disease

Jianyu Hou, Donghua Ji()   

  1. Department of Interventional Therapy, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China
  • Received:2025-05-20 Published:2026-02-25
  • Corresponding author: Donghua Ji
引用本文:

侯建宇, 纪东华. 炎症标志物与外周动脉疾病相关性的研究进展[J/OL]. 中华介入放射学电子杂志, 2026, 14(01): 97-102.

Jianyu Hou, Donghua Ji. Research Progress on the Correlation Between Inflammatory Markers and Peripheral Artery Disease[J/OL]. Chinese Journal of Interventional Radiology(Electronic Edition), 2026, 14(01): 97-102.

外周动脉疾病(peripheral artery disease, PAD)是由于下肢动脉管腔狭窄或闭塞,而引起患者间歇性跛行与静息痛的一种动脉粥样硬化性疾病。其发病率在世界范围内逐年升高,可导致心血管事件高发,其病理进程与全身性炎症反应密切相关。多种炎症标志物(如C反应蛋白、白细胞、白细胞介素等)不仅参与PAD的发生发展,还可作为预测疾病预后和治疗效果的潜在生物标志物。本文系统综述了多种炎症标志物与PAD的关联性,以及抗炎治疗策略的最新研究进展,旨在为PAD的诊疗提供理论依据。

Peripheral artery disease (PAD) is an atherosclerotic disorder characterized by lower extremity arterial stenosis or occlusion, leading to symptoms such as intermittent claudication and rest pain. Its incidence has been rising globally year by year and is associated with a high prevalence of cardiovascular events. The pathogenesis of PAD is closely linked to systemic inflammatory responses. Various inflammatory biomarkers, including C-reactive protein, white blood cells, interleukins, and others, not only contribute to the development and progression of PAD but also serve as potential biomarkers for predicting disease prognosis and treatment outcomes. This review systematically summarizes the associations between multiple inflammatory markers and PAD, as well as the latest research advances in anti-inflammatory therapeutic strategies, aiming to provide a theoretical basis for the diagnosis and management of PAD.

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