探讨原发性肝癌患者经肝动脉化疗栓塞术联合靶向及免疫治疗过程中的症状自我体验与心理感受，为完善症状管理提供依据。

采用现象学研究方法，对15例接受上述联合治疗的患者进行半结构式访谈，并运用Colaizzi 7步分析法进行资料分析。

归纳出4个主题，生理上面临栓塞综合征、睡眠障碍与治疗相关不良反应；心理上存在对不良反应的恐惧及疾病复发的忧虑；家庭与社会功能出现角色冲突、社交停滞及工作方式改变；应对方式则呈现积极与消极两种模式。

患者经受多方面、相互影响的症状困扰，医护人员应加强动态评估与整合管理，重视心理支持并促进家庭社会支持，以改善患者适应水平与就医体验。

To explore the symptom experience and psychological perceptions of patients with primary liver cancer during combined treatment with transarterial chemoembolization (TACE), targeted therapy, and immunotherapy, providing a basis for improved symptom management.

Using a phenomenological approach, semi-structured interviews were conducted with 15 patients receiving the combined therapy. Data were analyzed using Colaizzi's seven-step method.

Four main themes were identified: (1) physical symptoms, including post-embolization syndrome, sleep disturbances, and treatment-related adverse reactions; (2) psychological distress, involving fear of side effects and anxiety regarding recurrence; (3) social and family impact, including role conflicts, social withdrawal, and changes in work patterns; and (4) coping strategies, encompassing both active and passive modes.

Patients face multifaceted and interconnected symptoms. Healthcare professionals should implement dynamic assessments and integrated management, emphasizing psychological support and fostering family/social networks to improve patient adaptation and the overall care experience.