观察肝癌TACE术注入栓塞剂前应用利多卡因联合规范围手术期护理，对包括老年人群在内的肝癌患者的镇痛效果及对睡眠和生活质量的影响。

将100例拟行TACE术肝癌患者，按入院先后顺序分为两组各50例。两组均给予规范围手术期护理，观察组在TACE术中注入栓塞剂前一次性注入盐酸利多卡因注射液100 mg，对照组在注入栓塞剂前不注入利多卡因。两组均采用疼痛评分（视觉模拟评分法）、癌症患者生活质量量表、Spiegel量表评估两组术前、术后24 h疼痛、生活质量、睡眠情况。

两组术前生活质量评分、Spiegel量表评分比较及疼痛评分均无统计学意义（P > 0.05）。术后24 h生活质量评分，观察组（35.08 ± 9.50）与对照组（38.72 ± 10.9）比较无统计学意义（P > 0.05），观察组优于对照组；术后24 h Spiegel量表评分，观察组（11.56 ± 2.31）与对照组（9.02 ± 2.69）比较均有统计学意义（P < 0.001），观察组优于对照组；术后24 h疼痛视觉模拟评分，观察组（2.38 ± 1.47）与对照组（4.08 ± 1.59）比较有统计学意义（P < 0.001），观察组优于对照组。

TACE术中注入栓塞剂前应用利多卡因联合规范围手术期护理，可以减轻肝癌患者包括老年人群在内的术后疼痛，改善其睡眠质量。

To observe the analgesic effects of lidocaine injected before embolic agent injection in transarterial chemoembolization (TACE) combined with usual perioperative care on liver cancer patients, including the elderly, and its effect on sleep and quality of life.

A total of 100 patients with liver cancer undergoing TACE were enrolled into observation group or control group (in a 1: 1 ratio) according to the order of admission. Usual perioperative care was implemented in both of two groups. The patients in observation group were injected with 100 mg lidocaine hydrochloride injection before embolic agent injection during TACE, while the patients in the control group were not injected with lidocaine hydrochloride injection before embolic agent injection. The pain score (visual analogue scale), quality of life scale of cancer patients and Spiegel scale were used to evaluate the pain, quality of life and sleep of the two groups before operation and 24 h after operation.

There were no significant differences in preoperative quality of life score, Spiegel scale score and pain score between the two groups (P > 0.05). At 24 h after operation, there was no significant difference in quality of life between the two groups (35.08 ± 9.50 vs 38.72 ± 10.9, P > 0.05). At24 h after operation, the Spiegel scale score of the observation group (11.56 ± 2.31) was better than than that of the control group (9.02 ± 2.69), with statistically significant differences (P < 0.001). At 24 h after operation, The pain score (visual analogue scale) was lower in the observation group (2.38 ± 1.47) than that in the control group (4.08 ± 1.59), statistically significant differences (P < 0.001).

Injecting lidocaine before injecting embolization during TACE combined with usual perioperative care can reduce the postoperative pain and improve the quality of sleep of patients with liver cancer including the elderly.