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中华介入放射学电子杂志 ›› 2022, Vol. 10 ›› Issue (01) : 56 -60. doi: 10.3877/cma.j.issn.2095-5782.2022.01.010

影像诊断

病灶大小对肾脏嗜酸细胞腺瘤及嫌色细胞癌CT征象的影响
王国杰1, 秦培鑫1,(), 陈相猛2, 李坤炜1, 龙晚生2   
  1. 1. 519000 广东珠海,中山大学附属第五医院放射科
    2. 529000 广东江门,江门市中心医院放射科
  • 收稿日期:2021-05-29 出版日期:2022-02-25
  • 通信作者: 秦培鑫

The effect of size on CT findings of renal oncocytoma and chromophobe renal cell carcinoma

Guojie Wang1, Peixin Qin1,(), Xiangmeng Chen2, Kunwei Li1, Wansheng Long2   

  1. 1. Department of Radiology, the Fifth Affiliated Hospital of Sun Yat-sen University, Guangdong Zhuhai 519000
    2. Department of Radiology, Jiangmen Central Hospital, Guangdong Jiangmen 529000, China
  • Received:2021-05-29 Published:2022-02-25
  • Corresponding author: Peixin Qin
引用本文:

王国杰, 秦培鑫, 陈相猛, 李坤炜, 龙晚生. 病灶大小对肾脏嗜酸细胞腺瘤及嫌色细胞癌CT征象的影响[J]. 中华介入放射学电子杂志, 2022, 10(01): 56-60.

Guojie Wang, Peixin Qin, Xiangmeng Chen, Kunwei Li, Wansheng Long. The effect of size on CT findings of renal oncocytoma and chromophobe renal cell carcinoma[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2022, 10(01): 56-60.

目的

研究肾脏嗜酸细胞腺瘤(RO)与嫌色细胞癌(ChRCC)常见的CT鉴别征象是否与病灶大小相关,进一步提高诊断的准确性。

方法

回顾性分析病理证实的16例RO和21例ChRCC的CT图像,分析其平扫、增强特征是否存在差异,再将病例分为≤3 cm组(RO 8例,ChRCC 3例)、>3 cm组(RO 8例,ChRCC 18例),比较其特征在组间是否存在差异。

结果

(1)RO与ChRCC病灶大小无统计学差异(P = 0.118);(2)RO与ChRCC在节段性强化反转、辐轮状强化及皮髓期强化程度三种特征上存在统计学差异,P值分别为0.024、0.027、0.001,中央瘢痕、钙化两种征象无统计学差异,P值分别为0.520、0.071;(3)≤3 cm、> 3 cm组间中央瘢痕、节段性强化反转、钙化、皮髓期强化程度存在统计学差异,P值分别为0.000、0.011、0.015、0.002。

结论

综合分析病灶的大小及CT征象,有助于准确鉴别RO与ChRCC。

Objective

To explore common CT differential diagnosis findings between renal oncocytoma (RO) and chromophobe renal cell carcinoma (ChRCC) for different size lesions.

Methods

Double-blind methods were used to retrospectively analyze the CT images of 16 cases of RO and 21 cases of ChRCC. The CT features of different tumors were analyzed and compared. The cases were then divided into two groups according to size, ≤3 cm in diameter were classified as group one, and > 3 cm in diameter were classified as group two, the characteristics were compared between the two groups.

Results

(1) There was no statistically significant differences between RO and ChRCC in lesions diameter (P = 0.118); (2) Statistically significant differences between RO and ChRCC were shown in segmental enhancement inversion, spoke-wheel-like enhancement and degree of enhancement in the cortical phase (P = 0.024, 0.027, 0.001), but not shown in central scar and calcification (P = 0.520, 0.071); (3) There were statistically significant differences between group one and group two in central-scar, segmental enhancement inversion, calcification and degree of enhancement in the cortical phase (P = 0.000, 0.011, 0.015, 0.002).

Conclusions

Comprehensive analysis of lesion size and CT features is helpful for diagnosing and distinguishing RO and ChRCC accurately.

图1 男性,66岁,因车祸偶然发现左肾RO,直径约3.0 cm1A:左肾结节,CT平扫呈等密度;1B:皮髓期结节不均匀强化,部分区域呈高强化(箭头),部分区域轻度强化(三角);1C:实质期病灶不同区域强化反转,原皮髓期高强化区强化程度减低(箭头),原轻度强化区呈高强化(三角)。
图2 女性,29岁,血尿2 d,伴右腰部阵发性胀痛,右肾ChRCC,直径约7.0 cm2A:右肾类圆形肿块,CT平扫呈稍高密度,肿块中央见钙化斑(箭头);2B:皮髓期肿块不均匀强化,中央隐约见瘢痕(箭头);2C:实质期肿块强化程度减低,中央瘢痕消失。
图3 男性,64岁,4 d前无明显诱因出现右侧腰腹部疼痛,右肾ChRCC,直径约7.0 cm3A:CT平扫示右肾等、低混杂密度肿块;3B~3C:横轴位MIP图及冠状位MIP图,肿块内见辐轮状强化(箭头)。
图4 女性,53岁,体检发现右肾RO,直径约1.7 cm4A:结节平扫呈等密度;4B:皮髓期强化接近肾皮质;4C:质期强化程度减低。
表1 RO与ChRCC CT征象在≤3 cm组、>3 cm组出现的频率(例)
表2 不同CT征象在RO、ChRCC间及≤3 cm组、>3 cm组间统计学差异
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