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中华介入放射学电子杂志 ›› 2013, Vol. 01 ›› Issue (02) : 19 -23. doi: 10.3877/cma.j.issn.2095-5782.2013.02.005

血管介入

急诊介入治疗在胰腺疾病外科术后大出血中的应用研究
王志军1, 王茂强1,(), 宋鹏1, 段峰1, 刘凤永1, 刘志伟2, 樊庆胜1, 田利1   
  1. 1.100853 北京,中国人民解放军总医院介入放射科
    2.100853 北京,中国人民解放军总医院肝胆外科
  • 收稿日期:2013-04-12 出版日期:2013-11-01
  • 通信作者: 王茂强

Clinical application of transcatheter endovascular management in postoperative massive hemorrhage on pancreatic

Zhijun Wang1, Maoqiang Wang1,(), Peng Song1, Feng Duan1, Fengyong Liu1, Zhiwei Liu1, Qingsheng Fan1, Li Tian1   

  1. 1.Department of Interventional Radiology,Chinese PLA General Hospital,Beijing 100853,China
  • Received:2013-04-12 Published:2013-11-01
  • Corresponding author: Maoqiang Wang
引用本文:

王志军, 王茂强, 宋鹏, 段峰, 刘凤永, 刘志伟, 樊庆胜, 田利. 急诊介入治疗在胰腺疾病外科术后大出血中的应用研究[J]. 中华介入放射学电子杂志, 2013, 01(02): 19-23.

Zhijun Wang, Maoqiang Wang, Peng Song, Feng Duan, Fengyong Liu, Zhiwei Liu, Qingsheng Fan, Li Tian. Clinical application of transcatheter endovascular management in postoperative massive hemorrhage on pancreatic[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2013, 01(02): 19-23.

目的

评价介入治疗技术治疗胰腺疾病外科术后大出血的安全性和有效性。

方法

对20例胰腺疾病外科术后大出血患者进行介入治疗,单纯血管内栓塞18例,联合内支架植入1例,联合肠系膜上动脉局部灌注1例。栓塞材料用微型钢丝圈14例,普通钢丝圈2例,同时用聚乙烯醇微球6例,同时用明胶海绵4例。

结果

栓塞前选择性血管造影显示,单纯假性动脉瘤形成13例,合并对比剂外溢3例,单纯对比剂外溢3例,血管造影阴性1例。介入治疗止血成功率90.00%(18/20),20例中2例于次日因应激性溃疡大出血死亡。18例首次介入止血成功者有2例再发出血,再出血率11.11%(2/18)。18例介入治疗成功者,术后经输血、补液等对症处理后,生命体征平稳,引流管及胃管引流液血性液体消失。随访中,原有合并胰瘘、腹腔脓肿者2例因大出血、失血性休克而死亡,其余16例随访2周~24个月过程中,未再出现大出血。4例行肝固有动脉栓塞者介入术后谷丙转氨酶出现一过性升高,其他患者未出现肠坏死、胰腺坏死、脾脓肿表现。

结论

血管内介入治疗是治疗胰腺疾病外科术后大出血的安全有效方法。

Objective

To evaluate the efficacy and safety of the interventional techniques for treatment of postoperative massive hemorrhage on pancreatic diseases.

Methods

Twenty patients with postoperative hemorrhage were treated with endovascular interventional techniques,and 18 of them with only superselective arterial embolization,1 of them combined with stent placement and one combined with regional perfusion through SMA approach.The embolization devices were microcoils in 14 cases and standard stainless steel coils in 2 cases,associated with polyvinyl alcohol particles(PVA)in 6 cases and with gelfoams in 4 cases.

Results

Selective angiogram revealed the pseudoaneurysm in 13 cases,contrast media extravasation in 3 cases,pseudo aneurysm combined with contrast media extravasation in 3 cases.The technical success rate was 90.00%(18/20),and 2 died of massive hemorrhage associated with stress ulcer.Recurrent bleeding rate was 11.11%(2/18).Angiography demonstrated complete obliteration of relative vessels after embolization,and patency with stable blood flow of the hepatic artery after stent placement,18 patients with hemodynamically compromise experienced immediate relief of their blood loss related symptoms.Two patients with pancreatic fistula and intra-abdominal abscess recurred bleeding in two weeks and died of hemorrhagic shock.The other 16 patents didn't occur bleeding in the following 2 weeks to 24 months.ALT occurred temporary increase in 4 patients with proper hepatic arterial embolization.Other complications,such as intestinal and pancreatic necrosis were not cbserved.

Conclusions

Transcatheter endovascular techniques are safe and effective to treat postoperative massive hemorrhage on pancreatic diseases.

1
Jagad RB,Koshariya M,Kawamoto J,et al.Postoperative hemorrhage after major pancrea-tobiliary surgery:an update.Hepatogastroenterology,2008,55(82-83):729-737.
2
Santoro R,Carlini M,Carboni F.Delayed massive arterial hemorrhage after pancreaticoduodenectomy for cancer.Management of a lifethreatening complication.Hepatogastroenterology.2003,50(54):2199-2204.
3
Choi SH,Moon HJ,Heo JS,et al.Delayed hemorrhage after pancreaticoduodenectomy.J Am Coll Surg,2004;199(2):186-191.
4
Yoon YS,Kim SW,Her KH,et al.Management of postoperative hemorrhage after pancreatoduodenectomy.Hepatogastroenterology,2003,50(54):2208-2212.
5
Nosher JL,Chung J,Brevetti LS,et al.Visceral and renal artery aneurysms:a pictorial essay on endovascular therapy.RadioGraphics,2006,26(6):1687-1704.
6
Harvey J,Dardik H,Impeduglia T,et al.Endovascular management of hepatic artery pseudoaneurysm hemorrhage complicating pancreaticoduodenectomy.J Vasc Surg,2006,43(3):613-617.
7
Narumi S,Hakamda K,Toyoki Y,et al.Endovascular treatment of life-threaten-ing pseudoaneurysm of the hepatic artery after pancreaticoduodenectomy.Hepatogastroenterology,2007,54(79):2152-2154.
8
Makowiec F,Riediger H,Euringer W,et al.Management of delayed visceral arterial bleeding after pancreatic head resection.J Gastrointest Surg,2005,9(9):1293-1299.
9
Fujii Y,Shimada H,Endo I,et al.Management of massive arterial hemorrhage after pancreatobiliary surgery:does embolotherapy contribute to successful outcome?J Gastrointest Surg,2007,11(4):432-438.
10
Stoupis C,Ludwig K,Inderbitzin D,et al.Stent grafting of acute hepatic artery bleeding following pancreatic head resection.Eur Radiol,2007,17(2):401-408.
11
Hyare H,Desigan S,Brookes JA,et al.Endovascular management of major arterial hemorrhage as a complication of inflammatory pancreatic disease.J Vasc Interv Radiol,2007,18(5):591-596.
12
Lagana D,Carrafiello G,Mangini M,et al.Multimodal approach to endovascular treatment of visceral artery aneurysms and pseudoaneurysms.Eur J Radiol,2006,59(1):104-111.
13
陈耀庭,许林锋,江容坚,等.钢圈栓塞治疗肝动脉假性动脉瘤的临床观察.介入放射学杂志,2007,16(12):803-806.
14
李国华,杨卫宏,宋颖妹,等.胆胰术后出血的介入治疗.介入放射学杂志,2006,15(1):17-19.
15
Wallace MJ,Choi E,McRae S,et al.Superior mesenteric artery pseudoaneurysm following pancreaticoduodenectomy:manageme nt by endovascular stent-graft placement and transluminal thrombin injection.Cardiovasc Intervent Radiol,2007,30(3):518-522.
16
Iwama Y,Sugimoto K,Zamora CA,et al.Transcatheter embolization of splenic artery pseudoaneurysm rupturing into colon after post-operative pancreatitis.Cardiovasc Intervent Radiol,2006,29(1):133-136.
17
Tulsyan N,Kashyap VS,Greenberg RK,et al.The endovascular management of visceral artery aneurysms and pseudoaneurysms.J Vasc Surg,2007,45(2):276-283.
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