CT perfusion study of pre-and post-operative cerebral hemodynamics in patients with carotid artery stenting

doi:10.3877/cma j.issn.2095-5782.2014.01.014

Abstract

Abstract:

Objective

To evaluate the change of cerebral perfusion of patients with severe carotid stenosis before and after undergoing carotid artery stent placement（CAS）with CT perfusion（CTP）.

Methods

Twenty-two patients with carotid artery stenosis were underwent cerebral perfusion CT before and after the stentplacement procedure.Cerebral blood volume（CBV），cerebral blood flow（CBF）and mean transit time（MTT）values were measured.

Results

There was significant difference in preoperative bilateral cerebral perfusion of 19 cases with unilateral carotid artery stenosis.CBF of affected side was lower than that of uninjured side（21.90±3.37 vs 37.17±6.34，t=13.445，P﹤0.001）.MTT of affected side was longer than that of uninjured side（8.44±1.02 vs 5.75±0.81，t=9.605，P﹤0.001）.There was no significant difference between affected side and uninjured side（2.03±0.31 vs 2.14±0.25，t=1.204，P=0.2365）.The perfusion parameters of affected side was normalizing after CAS.

Conclusions

CTA combined with CTP is a useful technique for the assessment of the hemodynamic modifications in patients with severe carotid stenosis.The quantitative evaluation of cerebral perfusion makes it a reliable tool for the follow-up of patients who undergo CAS.

Key words: Liver transplantation, Hepatic artery stenosis, Stents

Hongtao Niu, Wenli Zhang, Renyou Zhai, Jianfeng Wang, Baojie Wei. CT perfusion study of pre-and post-operative cerebral hemodynamics in patients with carotid artery stenting[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2014, 02(01): 48-50.

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Figures/Tables 1

References 8

1	Dorros G. Carotid arterial obliterative disease： should endovascular revascularization（stent supported angioplasty） today supplant carotid endarterectomy［J］？J Intervent Cardiol，1996，9（3）：193-196.
2	Wholey MH， Al-Mubarek N， Wholey MH. Updated review of the global carotid artery stent registry［J］. Catheter and Cardiovasc Interv，2003，60（2）：259-266.
3	Cianfoni A， Colosimo C， Basile M， et al. Brain perfusion CT：principles， technique and clinical applications［J］. Radiol Med， 2007，112（8）：1225-1243.
4	Cenic A， Nabavi DG， Craen RA， et al. Dynamic CT measurement of cerebral blood flow：a validation study［J］.AJNR，1999，20（1）：63-73.
5	Grandin CB， Duprez TP， Smith AM， et al. Usefulness of magnetic resonance derived quantitative measurements of cerebral blood flow and volume in prediction of infarct growth in hyperacute stroke［J］.Stroke，2001，32（5）：1147-1153.
6	Wintermark M， Flanders AE， Velthuis B， et al. Perfusion-CT assessment of infarct core and penumbra： receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke［J］.Stroke，2006，37（4）：979-985.
7	Nederkoorn PJ，van der Graad Y，Myriam HM. Duplex ultrasound and magnetic resonance angiography compared with digital subtraction angiography in carotid artery stenosis：A systematic review［J］.Stroke，2003，34（5）：1324-1332.
8	Gaudiello F， Colangelo V， Bolacchi F， et al. Sixty-four-section CT cerebral perfusion evaluation in patients with carotid artery stenosis before and after stenting with a cerebral protection device［J］.AJNR，2008，29（5）：919-923.

CAS	患侧			对侧
CAS	CBV（ml/100 g）	CBF［ml/（100 g·min）］	MTT（s）	CBV（ml/100 g）	CBF［ml/（100 g·min）］	MTT（s）
术前	2.03±0.31	21.90±3.37^a、b	8.44±1.02^a、b	1.92±0.45	37.17±6.34^a	6.21±0.78^a
术后	2.14±0.25	35.22±2.70^b	5.75±0.81^b	2.02±0.32	38.05±5.37	6.01±0.59
t值	1.204	13.445	9.605	0.7894	0.4617	0.8914
P值	0.2365	＜0.001	＜0.001	0.4350	0.6471	0.3786

CAS	患侧			对侧
CAS	CBV（ml/100 g）	CBF［ml/（100 g·min）］	MTT（s）	CBV（ml/100 g）	CBF［ml/（100 g·min）］	MTT（s）
术前	2.03±0.31	21.90±3.37^a、b	8.44±1.02^a、b	1.92±0.45	37.17±6.34^a	6.21±0.78^a
术后	2.14±0.25	35.22±2.70^b	5.75±0.81^b	2.02±0.32	38.05±5.37	6.01±0.59
t值	1.204	13.445	9.605	0.7894	0.4617	0.8914
P值	0.2365	＜0.001	＜0.001	0.4350	0.6471	0.3786

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