运用多层螺旋CT探讨第一对角支开口处斑块形成的危险因素。

收集我院2017年5月至2020年5月同时行冠状动脉CT血管造影（CCTA）和冠状动脉造影的冠心病患者共94例，48例第一对角支开口处有斑块为观察组，46例第一对角支开口处无斑块为对照组。分析两组的血压、前降支狭窄程度和血流速度、前降支与第一对角支夹角的差异，并分析上述因素对第一对角支斑块形成的影响。

两组间的血压、前降支狭窄程度和血流速度、前降支与第一对角支夹角的差异具有统计学意义（P < 0.05），前降支狭窄程度和血压是第一对角支开口处形成斑块的危险因素，其OR值分别为1.030、1.128。

血压及前降支的狭窄程度是第一对角支斑块形成的危险因素，且随着血压的增高，前降支狭窄程度的增大，第一对角支开口处斑块的发生率增加。

To explore the risk factors of the first diagonal branch plaque by using Multisilice spiral CT.

A total of 94 patients with coronary heart disease who both underwent coronary computer tomography angiography (CCTA) and coronary angiography in our hospital were collected from May 2017 to May 2020. 48 cases with plaques at the ostium of the first diagonal branch were included in the experimental group and 46 cases without plaques at the ostium of the first diagonal branch were served as the control group. Blood pressure, stenosis severity and blood flow velocity of the left anterior descending artery (LAD), the bifurcation angle between LAD and the first diagonal branch were compared between two groups, and the correlation between the above factors and the first diagonal branch ostial plaque were analysed.

There were significant statistical differences (P < 0.05) between the two groups in blood pressure, stenosis severity and blood flow velocity of LAD, the angle between LAD and the first diagonal branch. LAD stenosis severity and blood pressure were risk factors for the first diagonal branch ostial plaque, and the OR values were 1.030 and 1.128 respectively.

LAD stenosis severity and blood pressure were risk factors for the first diagonal branch ostial plaque formation.With the increasing of blood pressure and LAD stenosis severity, the incidence rate of the first diagonal branch ostial plaque increased.