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中华介入放射学电子杂志 ›› 2019, Vol. 07 ›› Issue (02) : 163 -167. doi: 10.3877/cma.j.issn.2095-5782.2019.02.015

所属专题: 文献

综述

金属支架联合腔道内抗肿瘤技术治疗恶性胆道梗阻的研究现状及进展
陈建建1, 姚远1, 周学良1, 焦德超1, 韩新巍1,()   
  1. 1. 450052 河南郑州,郑州大学第一附属医院介入科
  • 收稿日期:2019-02-13 出版日期:2019-05-01
  • 通信作者: 韩新巍

Current status and research progress of metal stent combined with intraluminal antineoplastic technique in treatment of malignant biliary obstruction

Jianjian Chen1, Yuan Yao1, Xueliang Zhou1, Dechao Jiao1, Xinwei Han1,()   

  1. 1. Department of Interventional Radiology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
  • Received:2019-02-13 Published:2019-05-01
  • Corresponding author: Xinwei Han
  • About author:
    Corresponding author: Han Xinwei, Email:
引用本文:

陈建建, 姚远, 周学良, 焦德超, 韩新巍. 金属支架联合腔道内抗肿瘤技术治疗恶性胆道梗阻的研究现状及进展[J]. 中华介入放射学电子杂志, 2019, 07(02): 163-167.

Jianjian Chen, Yuan Yao, Xueliang Zhou, Dechao Jiao, Xinwei Han. Current status and research progress of metal stent combined with intraluminal antineoplastic technique in treatment of malignant biliary obstruction[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2019, 07(02): 163-167.

恶性胆道梗阻是由恶性肿瘤直接或间接引起的胆道梗阻性疾病,其主要临床表现为高胆红素血症、胆管扩张。超过50%的患者确诊时已处于晚期,已经失去了行根治性手术的机会。经皮肝穿胆道支架成形术可缓解胆道梗阻,是行之有效的姑息性疗法。目前对于恶性胆道梗阻的治疗,诸如药物洗脱支架、腔道内近距离放疗、腔道内消融、光动力治疗等腔道内抗肿瘤技术联合胆道支架植入术已在临床应用。现结合国内外最新文献,就恶性胆道梗阻的金属支架相关治疗现状及进展进行综述。

Malignant biliary obstruction is a biliary obstructive disease caused directly or indirectly by malignant tumors. Its main clinical manifestations are hyperbilirubinemia and bile duct dilatation. More than 50% of patients are in advanced stage of treatment and have lost the opportunity for radical surgery. Percutaneous transhepatic biliary stenting can relieve biliary obstruction and is an effective palliative treatment. At present, biliary metal stent implantation combined with endoluminal anti-tumor techniques, such as drug-eluting stent, intra-luminal brachytherapy, intracavitary ablation and photodynamic therapy, are emerging in clinical applications for the treatment of malignant biliary obstruction. Now according to the latest literatures at home and abroad, the current progress of interventional treatment of biliary metal stents for malignant biliary obstruction are summarized.

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