探讨应用Embosphere微球联合弹簧圈行支气管动脉栓塞术（BAE）治疗大咯血的临床疗效。

2014年10月至2016年1月经保守治疗无效行BAE的大咯血患者52例，其中25例单用Embosphere微球栓塞（EM组），27例采用Embosphere微球联合金属弹簧圈栓塞（MC组），所有病例均随访1年，对比分析其临床疗效。

52例患者均成功施行BAE，24 h总体有效止血率96.15%（50/52），两组内各有1例再次咯血，EM组及MC组止血有效率分别为96%（24/25）及96.3%（26/27）（P>0.05）。术后1年内共复发咯血9例（EM组7例，MC组2例），总复发率17.31%（9/52），术后3个月内，EM组及MC组的复发率分别为4%（1/25）及3.7%（1/27），差异无统计学意义（P>0.05），术后3~12个月，MC组复发率明显低于EM组（3.7% vs. 24%），差异有统计学意义（P<0.05）。

Embosphere微球联合金属弹簧圈能有效提高BAE的中远期疗效，减少咯血复发。

To evaluate the clinical efficacy of bronchial artery embolization (BAE) using combination of Embosphere microspheres and mechanical coils in treatment of massive hemoptysis.

During the period from October 2014 to January 2016, a total of 52 patients with massive hemoptysis who had failed to respond to medical management received BAE, among these, the clinical efficacy of massive hemoptysis patients treated with Embosphere microspheres (n=25, group EM) was compared with those treated with combination of Embosphere microspheres and mechanical coils (n=27, group MC) . All patients were followed up for 1 year.

BAE was successfully accomplished in all 52 patients with an effective rate of 96.15% for bleeding-cessation within 24 h. In each group there was 1 case of hemoptysis, without statistical significance (P>0.05) . Recurrence of hemoptysis within 1 year after BAE was seen in 9 patients (nEM=7, nMC=2, 8/52, 17.31%) . Recurrence of hemoptysis within 3 months after BAE was found in 1 patient in both EM and MC groups (P>0.05) . MC group had a lower recurrence rate than EM group during the follow-up period of 3~12 months after the procedure (3.7% vs 24%, P<0.05) .

Combination of Embosphere microspheres and mechanical coils can efficient improve the metaphase and long-term efficacy of BAE, and reduce the recurrence of hemoptysis.