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中华介入放射学电子杂志 ›› 2014, Vol. 02 ›› Issue (03) : 61 -64. doi: 10.3877/cma.j.issn.2095-5782.2014.03.017

所属专题: 文献

综述

肺癌抗血管生成治疗研究现状及进展
马春华1, 于海鹏2, 郭志2,()   
  1. 1. 30060 天津环湖医院
    2. 30060 天津医科附属肿瘤医院
  • 收稿日期:2013-06-17 出版日期:2014-08-01
  • 通信作者: 郭志

The Progress of Anti-angiogenesis Therapy for Lung Cancer

Chunhua Ma1, Haipeng Yu2, Zhi Guo2()   

  1. 1. Department of Intervention, Tianjin HuanHu Hospital, Tianjin cerebral vascular and neural degenerative disease key laboratory, Tianjin 300060, China
    2. Department of Intervention, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy , Tianjin 300060, China
  • Received:2013-06-17 Published:2014-08-01
  • Corresponding author: Zhi Guo
引用本文:

马春华, 于海鹏, 郭志. 肺癌抗血管生成治疗研究现状及进展[J/OL]. 中华介入放射学电子杂志, 2014, 02(03): 61-64.

Chunhua Ma, Haipeng Yu, Zhi Guo. The Progress of Anti-angiogenesis Therapy for Lung Cancer[J/OL]. Chinese Journal of Interventional Radiology(Electronic Edition), 2014, 02(03): 61-64.

肺癌是世界上最常见的恶性肿瘤之一。放化疗是晚期肺癌的标准治疗方式,但患者生存期仍维持在较低水平。研究发现肿瘤的发生及发展依赖肿瘤血管形成。血管内皮生长因子及其受体是重要的血管生成调节因子,参与肿瘤形成及发展的多个过程。抗肿瘤血管生成治疗为肺癌的综合治疗开辟新的途径。本文就肺癌抗血管生成治疗研究的现状及进展做一综述。

Lung cancer is one of the most common malignant tumor in the world. Radiotherapy and Chemotherapy are the standard treatments of Lung Cancer, but the patient survival time remains at a lower level. Studies found that the tumor’s occurrence and development relay on angiogenesis. Vascular Endothelial Growth Factor and its receptor are important angiogenesis adjustment factors,which are involved in tumor formation and development of multiple processes.Anti-angiogenesis therapy opens up new avenues for the treatment of Lung Cancer . The paper make a summary of the research present situation and progress of anti-angiogenesis therapy for Lung cancer.

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